Patents by Inventor Katherine Allison Stuart

Katherine Allison Stuart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11896642
    Abstract: Provided herein are synthetic bioconjugates comprising collagen-binding peptides covalently bound to chemically modified glycan backbones, compositions containing the same, and uses thereof.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: February 13, 2024
    Assignee: Symic Holdings, Inc.
    Inventors: John Eric Paderi, Glenn Prestwich, Katherine Allison Stuart, Harsha Kabra, Elvis Ikwa
  • Publication number: 20210290726
    Abstract: Provided herein are synthetic bioconjugates comprising collagen-binding peptides covalently bound to chemically modified glycan backbones, compositions containing the same, and uses thereof.
    Type: Application
    Filed: July 9, 2018
    Publication date: September 23, 2021
    Inventors: John Eric Paderi, Glenn Prestwich, Katherine Allison Stuart, Harsha Kabra, Elvis Ikwa
  • Patent number: 10689425
    Abstract: This invention relates to collagen-binding synthetic peptidoglycans and engineered collagen matrices comprising a collagen matrix and a collagen-binding synthetic peptidoglycan where the collagen-binding synthetic peptidoglycan can be aberrant or can have amino acid homology with a portion of the amino acid sequence of a protein or a proteoglycan that regulates collagen fibrillogenesis. The invention also relates to kits, compounds, compositions, and engineered graft constructs comprising such collagen-binding synthetic peptidoglycans or engineered collagen matrices and methods for their preparation and use.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: June 23, 2020
    Assignee: Purdue Research Foundation
    Inventors: Alyssa Panitch, John Eric Paderi, Kinam Park, Katherine Allison Stuart, Steve Higbee
  • Publication number: 20190022175
    Abstract: This disclosure provides extracellular matrix-binding synthetic peptidoglycans comprised of one or more synthetic peptides conjugated to a glycan and methods of their use.
    Type: Application
    Filed: December 18, 2017
    Publication date: January 24, 2019
    Inventors: Alyssa Panitch, John Eric Paderi, Shaili Sharma, Katherine Allison Stuart, Nelda Marie Vasquez-Portalatin
  • Publication number: 20180030091
    Abstract: This invention relates to collagen-binding synthetic peptidoglycans. More particularly, this invention relates to collagen-binding synthetic peptidoglycans for use in vascular intervention procedures. The invention also relates to kits comprising such collagen-binding synthetic peptidoglycans and catheters or stents.
    Type: Application
    Filed: September 22, 2017
    Publication date: February 1, 2018
    Applicant: Purdue Research Foundation
    Inventors: John Eric Paderi, Alyssa Panitch, Kinam Park, Katherine Allison Stuart
  • Patent number: 9872887
    Abstract: This disclosure provides extracellular matrix-binding synthetic peptidoglycans comprised of one or more synthetic peptides conjugated to a glycan and methods of their use.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: January 23, 2018
    Assignee: Purdue Research Foundation
    Inventors: Alyssa Panitch, John Eric Paderi, Shaili Sharma, Katherine Allison Stuart, Nelda Marie Vazquez-Portalatin
  • Publication number: 20170368192
    Abstract: This disclosure provides a method for improving maturation of an arteriovenous fistula (AVF) in a patient in need of hemodialysis, which method entails applying a solution to the internal wall of a lumen of an AVF; and restoring or initiating blood flow in the AVF, wherein the solution comprises an effective amount of a synthetic proteoglycan comprises a glycan having from about 1 to about 80 collagen-binding peptide(s) bonded to the glycan. Also provided are methods for preparing a vascular graft for a bypass surgery, comprising contacting the internal wall of a section of a blood vessel with a solution comprising an effective amount of the synthetic proteoglycan.
    Type: Application
    Filed: October 13, 2015
    Publication date: December 28, 2017
    Inventors: John Eric Paderi, Katherine Allison Stuart, Alyssa Panitch, Nathan Bachtell, Kenneth Horne
  • Publication number: 20170275345
    Abstract: This invention relates to collagen-binding synthetic peptidoglycans and engineered collagen matrices comprising a collagen matrix and a collagen-binding synthetic peptidoglycan where the collagen-binding synthetic peptidoglycan can be aberrant or can have amino acid homology with a portion of the amino acid sequence of a protein or a proteoglycan that regulates collagen fibrillogenesis. The invention also relates to kits, compounds, compositions, and engineered graft constructs comprising such collagen-binding synthetic peptidoglycans or engineered collagen matrices and methods for their preparation and use.
    Type: Application
    Filed: December 5, 2016
    Publication date: September 28, 2017
    Inventors: Alyssa Panitch, John Eric Paderi, Kinam Park, Katherine Allison Stuart, Steve Higbee
  • Publication number: 20170112941
    Abstract: This disclosure provides bioconjugate comprising a glycan and at least one peptide comprising a VE-Cadherin binding unit conjugated thereto, compositions comprising the same, and methods of use thereof.
    Type: Application
    Filed: October 12, 2016
    Publication date: April 27, 2017
    Inventors: Alyssa Panitch, John Eric Paderi, Katherine Allison Stuart, Seema Kantak, Nathan Bachtell
  • Patent number: 9512192
    Abstract: This invention relates to collagen-binding synthetic peptidoglycans and engineered collagen matrices comprising a collagen matrix and a collagen-binding synthetic peptidoglycan where the collagen-binding synthetic peptidoglycan can be aberrant or can have amino acid homology with a portion of the amino acid sequence of a protein or a proteoglycan that regulates collagen fibrillogenesis. The invention also relates to kits, compounds, compositions, and engineered graft constructs comprising such collagen-binding synthetic peptidoglycans or engineered collagen matrices and methods for their preparation and use.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: December 6, 2016
    Assignee: Purdue Research Foundation
    Inventors: Alyssa Panitch, John Eric Paderi, Kinam Park, Katherine Allison Stuart, Steve Higbee
  • Publication number: 20160244495
    Abstract: This invention relates to collagen-binding synthetic peptidoglycans and engineered collagen matrices comprising a collagen matrix and a collagen-binding synthetic peptidoglycan where the collagen-binding synthetic peptidoglycan can be aberrant or can have amino acid homology with a portion of the amino acid sequence of a protein or a proteoglycan that regulates collagen fibrillogenesis. The invention also relates to kits, compounds, compositions, and engineered graft constructs comprising such collagen-binding synthetic peptidoglycans or engineered collagen matrices and methods for their preparation and use.
    Type: Application
    Filed: March 23, 2016
    Publication date: August 25, 2016
    Applicant: Purdue Research Foundation
    Inventors: Alyssa Panitch, John Eric Paderi, Kinam Park, Katherine Allison Stuart, Steve Higbee
  • Publication number: 20160229895
    Abstract: This invention relates to collagen-binding synthetic peptidoglycans. More particularly, this invention relates to collagen-binding synthetic peptidoglycans for use in vascular intervention procedures. The invention also relates to kits comprising such collagen-binding synthetic peptidoglycans and catheters or stents.
    Type: Application
    Filed: February 12, 2016
    Publication date: August 11, 2016
    Applicant: Symic IP, LLC.
    Inventors: John Eric Paderi, Alyssa Panitch, Kinam Park, Katherine Allison Stuart
  • Publication number: 20160129076
    Abstract: This disclosure provides extracellular matrix-binding synthetic peptidoglycans comprised of one or more synthetic peptides conjugated to a glycan and methods of their use.
    Type: Application
    Filed: November 13, 2015
    Publication date: May 12, 2016
    Inventors: Alyssa Panitch, John Eric Paderi, Shaili Sharma, Katherine Allison Stuart, Nelda Marie Vazquez-Portalatin
  • Patent number: 9200039
    Abstract: This disclosure provides extracellular matrix-binding synthetic peptidoglycans comprised of one or more synthetic peptides conjugated to a glycan and methods of their use.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: December 1, 2015
    Assignee: SYMIC IP, LLC
    Inventors: Alyssa Panitch, John Eric Paderi, Shaili Sharma, Katherine Allison Stuart, Nelda Marie Vazquez-Portalatin
  • Publication number: 20140288002
    Abstract: This disclosure provides extracellular matrix-binding synthetic peptidoglycans comprised of one or more synthetic peptides conjugated to a glycan and methods of their use.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 25, 2014
    Inventors: Alyssa Panitch, John Eric Paderi, Shaili Sharma, Katherine Allison Stuart, Nelda Marie Vazquez-Portalatin