Patents by Inventor Kathrin Nollenberger
Kathrin Nollenberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11904056Abstract: A capsule shell contains 40 to 99% by weight of a core-shell polymer and 1 to 60% by weight of a cellulose. The core-shell polymer contains 50 to 90% by weight of a core, containing polymerized units of 65 to 75% by weight of ethyl acrylate and 25 to 35% by weight of methyl methacrylate; and 10 to 50% by weight of a shell, containing polymerized units of 45 to 55% by weight of ethyl acrylate and 45 to 55% by weight of methacrylic acid.Type: GrantFiled: March 5, 2020Date of Patent: February 20, 2024Assignee: Evonik Operations GmbHInventors: Bettina Hölzer, Manfred Aßmus, Kathrin Nollenberger
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Publication number: 20230203223Abstract: A novel methacrylic copolymer contains units derived from at least one alkyl methacrylate and methacrylamide. The units derived from methacrylamide are present in at least 34 wt.-%, based on the total weight of the methacrylic copolymer. A method can be used for preparing these novel methacylic copolymers. Pharmaceutical compositions, nutraceutical compositions, coated pharmaceutical or nutraceutical dosage forms, as well as nano- or microparticles can contain the methacrylic copolymer. The methacrylic copolymer can be used as a coating, as a carrier, and as a matrix for an amorphous solid dispersion.Type: ApplicationFiled: May 26, 2021Publication date: June 29, 2023Applicant: Evonik Operations GmbHInventors: Thomas Endres, Christian Moers, Fabian-Pascal Schmied, Jan Hendrik Schattka, Kathrin Nollenberger
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Publication number: 20220287345Abstract: The invention provides preparations comprising at least one polyunsaturated fatty acid salt for use in enhancing the solubility in aqueous media for a pharmaceutical or nutraceutical active ingredient in comparison to the pharmaceutical or nutraceutical active ingredient alone by at least 100%, preferably at least 300%. Moreover, a method for preparing a pharmaceutical or nutraceutical dosage form comprising at least one polyunsaturated fatty acid salt and at least one pharmaceutical or nutraceutical active ingredient is disclosed.Type: ApplicationFiled: August 7, 2020Publication date: September 15, 2022Applicant: Evonik Operations GmbHInventors: Ashish GUHA, Sonam SINGH, Shraddha JOSHI, Peter NIEPOTH, Kathrin NOLLENBERGER, Prajakta SURVE, Priyanka HAKSAR
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Publication number: 20220142929Abstract: A capsule shell contains 40 to 99% by weight of a core-shell polymer and 1 to 60% by weight of a cellulose. The core-shell polymer contains 50 to 90% by weight of a core, containing polymerized units of 65 to 75% by weight of ethyl acrylate and 25 to 35% by weight of methyl methacrylate; and 10 to 50% by weight of a shell, containing polymerized units of 45 to 55% by weight of ethyl acrylate and 45 to 55% by weight of methacrylic acid.Type: ApplicationFiled: March 5, 2020Publication date: May 12, 2022Applicant: Evonik Operations GmbHInventors: Bettina Hölzer, Manfred Aßmus, Kathrin Nollenberger
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Patent number: 9844511Abstract: The invention relates to a coating composition suitable for the coating of a pharmaceutical or nutraceutical dosage form, comprising a core comprising one or more pharmaceutical or nutraceutical active ingredients, wherein the coating composition is comprising at least 20% by weight of an enteric core/shell polymer composition derived from an emulsion polymerization process, wherein either the core of the core/shell polymer composition is formed by a water-insoluble, not cross-linked polymer or copolymer and the shell of the core/shell polymer composition is formed by an anionic polymer or copolymer or vice versa.Type: GrantFiled: June 17, 2011Date of Patent: December 19, 2017Assignee: Evonik Roehm GmbHInventors: Kathrin Nollenberger, Jan Hendrik Schattka, Rene Leubert, Florian Hermes, Manfred Assmus, Christian Meier, Thomas Dassinger, Thomas Riermeier
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Patent number: 9284416Abstract: The present invention provides a process for converting a solid (meth)acrylate copolymer into a dispersed form by preparing an aqueous dispersion comprising the components (a) a (meth)acrylate copolymer which is composed of free-radical polymerized methyl methacrylate, ethylacrylate and a salt of 2-trimethylammoniumethyl methacrylate, present in solid form as a powder or as a granulate, (b) up to 50% by weight calculated on the (meth)acrylate copolymer (a) of a dispersing agent selected from the groups of (b) i) plasticizers in combination with emulsifiers and/or (b) ii) pharmaceutically acceptable carbohydrates having 6 to 18 carbon atoms with a functional group and (c) water by mixing the components (a), (b) and (c) to give a suspension which becomes an aqueous dispersion during the conversion of the solid (meth)acrylate copolymer into the dispersed form, characterized in that, the (meth)acrylate copolymer is converted into the dispersed form by means of the presence of the dispersing agent at a temperatureType: GrantFiled: November 16, 2009Date of Patent: March 15, 2016Assignee: Evonik Roehm GmbHInventors: Erna Roth, Ruediger Alexowsky, Hans-Ulrich Petereit, Kathrin Nollenberger, Christian Meier
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Publication number: 20140086997Abstract: The invention relates to a coating composition suitable for the coating of a pharmaceutical or nutraceutical dosage form, comprising a core comprising one or more pharmaceutical or nutraceutical active ingredients, wherein the coating composition is comprising at least 20% by weight of an enteric core/shell polymer composition derived from an emulsion polymerisation process, wherein either the core of the core/shell polymer composition is formed by a water-insoluble, not cross-linked polymer or copolymer and the shell of the core/shell polymer composition is formed by an anionic polymer or copolymer or vice versa.Type: ApplicationFiled: June 17, 2011Publication date: March 27, 2014Applicant: Evonik Roehm GmbHInventors: Kathrin Nollenberger, Jan Hendrik Schattka, Rene Leubert, Florian Hermes, Manfred Assmus, Christian Meier, Thomas Dassinger, Thomas Riermeier
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Publication number: 20130142877Abstract: The invention relates to a pharmaceutical dosage form comprising one or more antiretroviral active ingredients in the form of a solid dispersion or solid solution in a matrix, wherein said matrix comprises an amino(meth)acrylate copolymer, characterized in that the matrix does not contain any essential amounts of pharmaceutically acceptable surfactants with an HLB value from 12 to 18 and in that the matrix comprises a mono carboxylic acid or an alcohol with 12 to 22 carbon atoms or both.Type: ApplicationFiled: March 3, 2011Publication date: June 6, 2013Applicant: EVONIK ROEHM GmbHInventors: Pravin Nalawade, Smitha Shetty, Hema Ravishankar, Shripad Gadhinglajkar, Andreas Gryczke, Hans-Ulrich Petereit, Kathrin Nollenberger
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Publication number: 20120208832Abstract: The present invention provides a process for converting a solid (meth)acrylate copolymer into a dispersed form by preparing an aqueous dispersion comprising the components (a) a (meth)acrylate copolymer which is composed of free-radical polymerized methyl methacrylate, ethylacrylate and a salt of 2-trimethylammoniumethyl methacrylate, present in solid form as a powder or as a granulate, (b) up to 50% by weight calculated on the (meth)acrylate copolymer (a) of a dispersing agent selected from the groups of (b) i) plasticizers in combination with emulsifiers and/or (b) ii) pharmaceutically acceptable carbohydrates having 6 to 18 carbon atoms with a functional group and (c) water by mixing the components (a), (b) and (c) to give a suspension which becomes an aqueous dispersion during the conversion of the solid (meth)acrylate copolymer into the dispersed form, characterized in that, the (meth)acrylate copolymer is converted into the dispersed form by means of the presence of the dispersing agent at a temperatureType: ApplicationFiled: November 16, 2009Publication date: August 16, 2012Applicant: Evonik Roehm GmbHInventors: Erna Roth, Ruediger Alexowsky, Hans-Ulrich Petereit, Kathrin Nollenberger, Christian Meier
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Publication number: 20090011007Abstract: The invention relates to a pharmaceutical composition comprising a mixture of at least one cationic, water-soluble (meth)acrylate copolymer, at least one water-insoluble polymer and at least one active ingredient having a solubility in demineralized water of 3.3 g/l or less, characterized in that the water-insoluble polymer and the active ingredient are present in a ratio of at most 3.5 to 1 parts by weight, and the pharmaceutical composition has the property of releasing the active ingredient present in a medium buffered to pH 1.2 in dissolved form in a concentration which, after 2 hours at pH 1.2, corresponds to at least sixteen times the solubility value of the active ingredient alone at pH 1.2.Type: ApplicationFiled: January 17, 2007Publication date: January 8, 2009Applicant: Evonik Roehm GmbHInventors: Christian Meier, Kathrin Nollenberger, Andreas Gryczke, Hans-Ulrich Petereit, Jennifer Dressman
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Publication number: 20080206324Abstract: An active compound-containing pellet has a polymer coating of an anionic (meth)acrylate copolymer and a pharmaceutically active substance, embedded in a polymer matrix of one or more polymers, a particle size in the range from 300 to 1100 ?m, a friability of at most 0.1%, measured using 200 g of pellets in a screening machine having a 200 ?m screen, a screening diameter of 20 cm and 1.5 mm shaking amplitude at a shaking frequency of 50 l/sec for 10 min in the presence of six rubber cubes having a 1.8 cm edge length, with the proviso that the pellet releases no more than 10% of the active compound in a release test according to USP in artificial gastric juice at pH 1.2 after 120 min.Type: ApplicationFiled: February 13, 2008Publication date: August 28, 2008Applicant: Evonik Roehm GmbHInventors: Andreas Gryczke, Hans-Ulrich Petereit, Christian Meier, Kathrin Nollenberger, Christian Brunnengraber, Andreas Klosendorf, Reinhard Menzel