Patents by Inventor Kazuhiko Fujisawa

Kazuhiko Fujisawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120283381
    Abstract: The present invention relates to macroinitiators comprising at least one hydrophobic segments in a molecule, wherein a molecular weight of the hydrophobic segment is 300 to 1800. The present invention further relates to block copolymers, wetting agent and polymeric materials having the block copolymers of the present invention associated with, which is suitable for medical devices, particularly for ophthalmic devices, including contact lenses, ophthalmic lenses, punctal plugs and artificial corneas.
    Type: Application
    Filed: April 18, 2012
    Publication date: November 8, 2012
    Inventors: Ryuta Tamiya, Kazuhiko Fujisawa, Masataka Nakamura
  • Patent number: 8242187
    Abstract: A silicone polymer having sufficient antibacterial properties and high transparency; and Ophthalmic lenses made of the polymer, such as a contact lens, and artificial cornea. The silicone polymer is characterized by being obtained by and a monomer having an ammonium salt in the molecule.
    Type: Grant
    Filed: September 27, 2007
    Date of Patent: August 14, 2012
    Assignee: Toray Industries, Inc.
    Inventors: Kazuhiko Fujisawa, Tsutomu Goshima, Masataka Nakamura
  • Publication number: 20120065348
    Abstract: In one aspect, the invention relates to silicon-based prepolymers. The disclosed prepolymers exhibit satisfactory solubility in aqueous solutions or hydrophilic solutions and can overcome undesirable shrinkage, expansion, and related problems possessed by conventional silicone monomers and related conventional polymerization techniques by producing hydrogels from a crosslinkable prepolymer. Also disclosed are polymers and molded articles produced from the disclosed prepolymers, which attain a satisfactory oxygen permeability. Also disclosed are methods for producing the disclosed prepolymers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: November 19, 2011
    Publication date: March 15, 2012
    Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
  • Patent number: 8080622
    Abstract: In one aspect, the invention relates to silicon-based prepolymers. The disclosed prepolymers exhibit satisfactory solubility in aqueous solutions or hydrophilic solutions and can overcome undesirable shrinkage, expansion, and related problems possessed by conventional silicone monomers and related conventional polymerization techniques by producing hydrogels from a crosslinkable prepolymer. Also disclosed are polymers and molded articles produced from the disclosed prepolymers, which attain a satisfactory oxygen permeability. Also disclosed are methods for producing the disclosed prepolymers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: December 20, 2011
    Assignees: Johnson & Johnson Vision Care, Inc., Toray Industries Inc.
    Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
  • Patent number: 8053539
    Abstract: In one aspect, the invention relates to compositions comprising siloxanyl compounds comprising the structure: or residues thereof. Such compositions can be suitable for producing molded articles, can be excellent in transparency, hydrophilicity, and oxygen permeability, and can have a low modulus of elasticity and/or an excellent optical quality, so as to be suitable for ophthalmic lenses such as contact lenses and intraocular lenses. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: December 12, 2006
    Date of Patent: November 8, 2011
    Assignees: Johnson & Johnson Vision Care Inc., Toray Industries Inc.
    Inventors: Masataka Nakamura, Kazuhiko Fujisawa, Mitsuru Yokota
  • Publication number: 20110237766
    Abstract: The present invention relates to a silicone (meth)acrylamide monomer, and this silicone (meth)acrylamide monomer is particularly suitable for use in contact lenses, intraocular lenses, artificial cornea, and the like.
    Type: Application
    Filed: March 15, 2011
    Publication date: September 29, 2011
    Inventors: Thomas L. Maggio, Michelle Carman Turnage, Michael R. Clark, Kazuhiko Fujisawa, Masataka Nakamura
  • Publication number: 20110230589
    Abstract: The present invention provides transparent silicone hydrogels with high acrylamide monomer content and an excellent balance between moisture content. The silicone hydrogels may be obtained by polymerizing a monomer mix containing a plurality of monomers, wherein the monomer mix comprises about 30 to about 98% by weight of at least one type of silicone monomer which is, and about 1 to about 50% by weight of at least one type of non-silicone type (meth)acrylamide monomer containing two or more hydroxyl groups within a molecule; wherein the weight percents are based upon the total amount of monomer components and polymer components in the monomer mix.
    Type: Application
    Filed: March 15, 2011
    Publication date: September 22, 2011
    Inventors: Thomas L. Maggio, Michelle Carman Turnage, Kazuhiko Fujisawa, Masataka Nakamura
  • Publication number: 20110160385
    Abstract: To obtain a hydrophilic macromonomer mixture which is a highly polymerized hydrophilic macromonomer, has few components not bonded to the polymer chain after polymerization, and is less likely to leaching. Provided is a macromonomer mixture containing macromonomer A being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a polymerization initiator at an end thereof; and macromonomer B being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a chain transfer agent at an end thereof.
    Type: Application
    Filed: December 22, 2010
    Publication date: June 30, 2011
    Inventors: Kazuhiko Fujisawa, Masataka Nakamura
  • Publication number: 20110077322
    Abstract: In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 7, 2010
    Publication date: March 31, 2011
    Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
  • Patent number: 7897654
    Abstract: In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: April 1, 2008
    Date of Patent: March 1, 2011
    Assignees: Johnson & Johnson Vision Care Inc., Toray Industries Inc.
    Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
  • Publication number: 20110028673
    Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: October 8, 2010
    Publication date: February 3, 2011
    Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota, Douglas G. Vanderlaan
  • Publication number: 20110008403
    Abstract: A medical antimicrobial composition includes a siloxanyl structure-containing polymer and an ammonium group-containing polymer, which is excellent in transparency, flexibility and mechanical properties, and also excellent in adhesion to a base resin with good mechanical properties, particularly to a silicone resin. The medical antimicrobial composition includes an ammonium group-containing polymer compound (A) dispersed in a siloxanyl structure-containing polymer (B) and a medical device comprising the medical antimicrobial composition.
    Type: Application
    Filed: March 5, 2009
    Publication date: January 13, 2011
    Applicant: Toray Industries, Inc.
    Inventors: Masataka Nakamura, Kazuhiko Fujisawa, Tsutomu Goshima
  • Patent number: 7838698
    Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: November 23, 2010
    Assignees: Johnson & Johnson Vision Care, Inc., Toray Industries, Inc.
    Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota, Douglas G. Vanderlaan
  • Patent number: 7683206
    Abstract: This invention provides a process for producing of a silicone compound which includes a synthesis reaction of a silicone compound represented by the following formulas (a) and/or (a?), by reacting a carboxylic acid represented by the following formula (a2) to an epoxy silane represented by the following formula (a1) in presence of a metal salt of the carboxylic acid represented by the general formula (a2), characterized in that the reaction is carried out in presence of 0.05 wt % or more water in said reaction system. Here, A denotes siloxanyl group. R1 denotes a substitutent with 1 to 20 carbons having a polymerizable group. R2 to R4 respectively and independently denote hydrogen, a substituted or unsubstituted substitutent with 1 to 20 carbons, or —X-A. X denotes a substituted or unsubstituted divalent substitutent with 1 to 20 carbons.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: March 23, 2010
    Assignee: Toray Industries, Inc.
    Inventors: Kazuhiko Fujisawa, Tsutomu Goshima, Mitsuru Yokota
  • Publication number: 20100056738
    Abstract: A silicone polymer having sufficient antibacterial properties and high transparency; and Ophthalmic lenses made of the polymer, such as a contact lens, and artificial cornea. The silicone polymer is characterized by being obtained by and a monomer having an ammonium salt in the molecule.
    Type: Application
    Filed: September 27, 2007
    Publication date: March 4, 2010
    Applicant: TORAY Industries, Inc.
    Inventors: Kazuhiko Fujisawa, Tsutomu Goshima, Masataka Nakamura
  • Publication number: 20090171026
    Abstract: In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: April 1, 2008
    Publication date: July 2, 2009
    Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
  • Publication number: 20090005528
    Abstract: In one aspect, the invention relates to silicon-based prepolymers. The disclosed prepolymers exhibit satisfactory solubility in aqueous solutions or hydrophilic solutions and can overcome undesirable shrinkage, expansion, and related problems possessed by conventional silicone monomers and related conventional polymerization techniques by producing hydrogels from a crosslinkable prepolymer. Also disclosed are polymers and molded articles produced from the disclosed prepolymers, which attain a satisfactory oxygen permeability. Also disclosed are methods for producing the disclosed prepolymers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: June 29, 2007
    Publication date: January 1, 2009
    Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
  • Publication number: 20080081894
    Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: November 20, 2006
    Publication date: April 3, 2008
    Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota, Douglas G. Vanderlaan
  • Publication number: 20080081850
    Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: November 20, 2006
    Publication date: April 3, 2008
    Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota
  • Patent number: 7329694
    Abstract: This invention provides an ophthalmic lens of high tensile elongation (i.e., that does not break easily). It is an ophthalmic lens comprising, as a polymerization component, monomers represented by formula (a) below: wherein, in formula (a), R1 is H or a methyl group; R2 is a group that is selected from alkyl groups with 1 to 8 carbon atoms, aralkyl groups with 7 to 12 carbon atoms and aryl groups with 6 to 10 carbon atoms; L1 is a substituent that is selected from ethylene groups, 1,2-propylene groups, 1,3-propylene groups and 1,4-butylene groups; and L2 is a substituent that is selected from methylene groups, ethylene groups, 1,2-propylene groups, 1,3-propylene groups and 1,4-butylene groups.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: February 12, 2008
    Assignee: Johnson & Johnson Vision Care, Inc.
    Inventors: Masataka Nakamura, Kazuhiko Fujisawa, Naoki Shimoyama, Mitsuru Yokota