Patents by Inventor Kazuhiko Fujisawa
Kazuhiko Fujisawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8357818Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: October 8, 2010Date of Patent: January 22, 2013Assignees: Johnson & Johnson Vision Care, Inc., Toray Industries, Inc.Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota, Douglas G. Vanderlaan
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Publication number: 20120283381Abstract: The present invention relates to macroinitiators comprising at least one hydrophobic segments in a molecule, wherein a molecular weight of the hydrophobic segment is 300 to 1800. The present invention further relates to block copolymers, wetting agent and polymeric materials having the block copolymers of the present invention associated with, which is suitable for medical devices, particularly for ophthalmic devices, including contact lenses, ophthalmic lenses, punctal plugs and artificial corneas.Type: ApplicationFiled: April 18, 2012Publication date: November 8, 2012Inventors: Ryuta Tamiya, Kazuhiko Fujisawa, Masataka Nakamura
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Patent number: 8242187Abstract: A silicone polymer having sufficient antibacterial properties and high transparency; and Ophthalmic lenses made of the polymer, such as a contact lens, and artificial cornea. The silicone polymer is characterized by being obtained by and a monomer having an ammonium salt in the molecule.Type: GrantFiled: September 27, 2007Date of Patent: August 14, 2012Assignee: Toray Industries, Inc.Inventors: Kazuhiko Fujisawa, Tsutomu Goshima, Masataka Nakamura
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Publication number: 20120065348Abstract: In one aspect, the invention relates to silicon-based prepolymers. The disclosed prepolymers exhibit satisfactory solubility in aqueous solutions or hydrophilic solutions and can overcome undesirable shrinkage, expansion, and related problems possessed by conventional silicone monomers and related conventional polymerization techniques by producing hydrogels from a crosslinkable prepolymer. Also disclosed are polymers and molded articles produced from the disclosed prepolymers, which attain a satisfactory oxygen permeability. Also disclosed are methods for producing the disclosed prepolymers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: ApplicationFiled: November 19, 2011Publication date: March 15, 2012Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
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Patent number: 8080622Abstract: In one aspect, the invention relates to silicon-based prepolymers. The disclosed prepolymers exhibit satisfactory solubility in aqueous solutions or hydrophilic solutions and can overcome undesirable shrinkage, expansion, and related problems possessed by conventional silicone monomers and related conventional polymerization techniques by producing hydrogels from a crosslinkable prepolymer. Also disclosed are polymers and molded articles produced from the disclosed prepolymers, which attain a satisfactory oxygen permeability. Also disclosed are methods for producing the disclosed prepolymers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: June 29, 2007Date of Patent: December 20, 2011Assignees: Johnson & Johnson Vision Care, Inc., Toray Industries Inc.Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
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Patent number: 8053539Abstract: In one aspect, the invention relates to compositions comprising siloxanyl compounds comprising the structure: or residues thereof. Such compositions can be suitable for producing molded articles, can be excellent in transparency, hydrophilicity, and oxygen permeability, and can have a low modulus of elasticity and/or an excellent optical quality, so as to be suitable for ophthalmic lenses such as contact lenses and intraocular lenses. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: December 12, 2006Date of Patent: November 8, 2011Assignees: Johnson & Johnson Vision Care Inc., Toray Industries Inc.Inventors: Masataka Nakamura, Kazuhiko Fujisawa, Mitsuru Yokota
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Publication number: 20110237766Abstract: The present invention relates to a silicone (meth)acrylamide monomer, and this silicone (meth)acrylamide monomer is particularly suitable for use in contact lenses, intraocular lenses, artificial cornea, and the like.Type: ApplicationFiled: March 15, 2011Publication date: September 29, 2011Inventors: Thomas L. Maggio, Michelle Carman Turnage, Michael R. Clark, Kazuhiko Fujisawa, Masataka Nakamura
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Publication number: 20110230589Abstract: The present invention provides transparent silicone hydrogels with high acrylamide monomer content and an excellent balance between moisture content. The silicone hydrogels may be obtained by polymerizing a monomer mix containing a plurality of monomers, wherein the monomer mix comprises about 30 to about 98% by weight of at least one type of silicone monomer which is, and about 1 to about 50% by weight of at least one type of non-silicone type (meth)acrylamide monomer containing two or more hydroxyl groups within a molecule; wherein the weight percents are based upon the total amount of monomer components and polymer components in the monomer mix.Type: ApplicationFiled: March 15, 2011Publication date: September 22, 2011Inventors: Thomas L. Maggio, Michelle Carman Turnage, Kazuhiko Fujisawa, Masataka Nakamura
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Publication number: 20110160385Abstract: To obtain a hydrophilic macromonomer mixture which is a highly polymerized hydrophilic macromonomer, has few components not bonded to the polymer chain after polymerization, and is less likely to leaching. Provided is a macromonomer mixture containing macromonomer A being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a polymerization initiator at an end thereof; and macromonomer B being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a chain transfer agent at an end thereof.Type: ApplicationFiled: December 22, 2010Publication date: June 30, 2011Inventors: Kazuhiko Fujisawa, Masataka Nakamura
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Publication number: 20110077322Abstract: In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: ApplicationFiled: December 7, 2010Publication date: March 31, 2011Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
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Patent number: 7897654Abstract: In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: April 1, 2008Date of Patent: March 1, 2011Assignees: Johnson & Johnson Vision Care Inc., Toray Industries Inc.Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
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Publication number: 20110028673Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: ApplicationFiled: October 8, 2010Publication date: February 3, 2011Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota, Douglas G. Vanderlaan
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Publication number: 20110008403Abstract: A medical antimicrobial composition includes a siloxanyl structure-containing polymer and an ammonium group-containing polymer, which is excellent in transparency, flexibility and mechanical properties, and also excellent in adhesion to a base resin with good mechanical properties, particularly to a silicone resin. The medical antimicrobial composition includes an ammonium group-containing polymer compound (A) dispersed in a siloxanyl structure-containing polymer (B) and a medical device comprising the medical antimicrobial composition.Type: ApplicationFiled: March 5, 2009Publication date: January 13, 2011Applicant: Toray Industries, Inc.Inventors: Masataka Nakamura, Kazuhiko Fujisawa, Tsutomu Goshima
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Patent number: 7838698Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: November 20, 2006Date of Patent: November 23, 2010Assignees: Johnson & Johnson Vision Care, Inc., Toray Industries, Inc.Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota, Douglas G. Vanderlaan
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Patent number: 7683206Abstract: This invention provides a process for producing of a silicone compound which includes a synthesis reaction of a silicone compound represented by the following formulas (a) and/or (a?), by reacting a carboxylic acid represented by the following formula (a2) to an epoxy silane represented by the following formula (a1) in presence of a metal salt of the carboxylic acid represented by the general formula (a2), characterized in that the reaction is carried out in presence of 0.05 wt % or more water in said reaction system. Here, A denotes siloxanyl group. R1 denotes a substitutent with 1 to 20 carbons having a polymerizable group. R2 to R4 respectively and independently denote hydrogen, a substituted or unsubstituted substitutent with 1 to 20 carbons, or —X-A. X denotes a substituted or unsubstituted divalent substitutent with 1 to 20 carbons.Type: GrantFiled: February 25, 2005Date of Patent: March 23, 2010Assignee: Toray Industries, Inc.Inventors: Kazuhiko Fujisawa, Tsutomu Goshima, Mitsuru Yokota
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Publication number: 20100056738Abstract: A silicone polymer having sufficient antibacterial properties and high transparency; and Ophthalmic lenses made of the polymer, such as a contact lens, and artificial cornea. The silicone polymer is characterized by being obtained by and a monomer having an ammonium salt in the molecule.Type: ApplicationFiled: September 27, 2007Publication date: March 4, 2010Applicant: TORAY Industries, Inc.Inventors: Kazuhiko Fujisawa, Tsutomu Goshima, Masataka Nakamura
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Publication number: 20090171026Abstract: In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: ApplicationFiled: April 1, 2008Publication date: July 2, 2009Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
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Publication number: 20090005528Abstract: In one aspect, the invention relates to silicon-based prepolymers. The disclosed prepolymers exhibit satisfactory solubility in aqueous solutions or hydrophilic solutions and can overcome undesirable shrinkage, expansion, and related problems possessed by conventional silicone monomers and related conventional polymerization techniques by producing hydrogels from a crosslinkable prepolymer. Also disclosed are polymers and molded articles produced from the disclosed prepolymers, which attain a satisfactory oxygen permeability. Also disclosed are methods for producing the disclosed prepolymers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: ApplicationFiled: June 29, 2007Publication date: January 1, 2009Inventors: Kazuhiko Fujisawa, Mitsuru Yokota, Masataka Nakamura
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Publication number: 20080081894Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: ApplicationFiled: November 20, 2006Publication date: April 3, 2008Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota, Douglas G. Vanderlaan
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Publication number: 20080081850Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: ApplicationFiled: November 20, 2006Publication date: April 3, 2008Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota