Abstract: Provided is a substance capable of effectively suppressing cancer metastasis or a pharmaceutical composition that effectively acts on an inflammatory disease. The pharmaceutical composition is a pharmaceutical composition containing, as an active ingredient, an antibody or an antibody fragment thereof having antigen-binding activity for an S100A8/A9 heterodimer, and blocks interaction between S100A8/A9 and a group of receptors therefor, to thereby strongly suppress cancer metastasis both in vitro and in vivo, or alleviate inflammation. That is, the anti-S100A8/A9 antibody or the antibody fragment thereof can strongly suppress cancer metastasis or alleviate inflammation, by virtue of its blocking action on the interaction between S100A8/A9 and the group of receptors therefor.

Abstract: A ruthenium complex of the following formula (1), a production method thereof, and uses of the ruthenium complex are disclosed. A method for producing the ruthenium complex includes a process of reacting a specific ruthenium complex with a borohydride compound. The ruthenium complex can be used as a catalyst in a production of optically active secondary alcohols.

Abstract: The present invention provides a carrier-attached copper foil, wherein an ultrathin copper foil is not peeled from the carrier prior to the lamination to an insulating substrate, but can be peeled from the carrier after the lamination to the insulating substrate. A carrier-attached copper foil comprising a copper foil carrier, an intermediate layer laminated on the copper foil carrier, and an ultrathin copper layer laminated on the intermediate layer, wherein the intermediate foil is configured with a Ni layer in contact with an interface of the copper foil carrier and a Cr layer in contact with an interface of the ultrathin copper layer, said Ni layer containing 1,000-40,000 ?g/dm2 of Ni and said Cr layer containing 10-100 ?g/dm2 of Cr is provided.

Abstract: The present invention provides a carrier-attached copper foil, wherein an ultrathin copper foil is not peeled from the carrier prior to the lamination to an insulating substrate, but can be peeled from the carrier after the lamination to the insulating substrate. A carrier-attached copper foil comprising a copper foil carrier, an intermediate layer laminated on the copper foil carrier, and an ultrathin copper layer laminated on the intermediate layer, wherein the intermediate foil is configured with a Ni layer in contact with an interface of the copper foil carrier and a Cr layer in contact with an interface of the ultrathin copper layer, said Ni layer containing 1,000-40,000 ?g/dm2 of Ni and said Cr layer containing 10-100 ?g/dm2 of Cr is provided.

Abstract: The present invention provides a carrier-attached copper foil, wherein an ultrathin copper foil is not peeled from the carrier prior to the lamination to an insulating substrate, but can be peeled from the carrier after the lamination to the insulating substrate. A carrier-attached copper foil comprising a copper foil carrier, an intermediate layer laminated on the copper foil carrier, and an ultrathin copper layer laminated on the intermediate layer, wherein the intermediate foil is configured with a Ni layer in contact with an interface of the copper foil carrier and a Cr layer in contact with an interface of the ultrathin copper layer, said Ni layer containing 1,000-40,000 ?g/dm2 of Ni and said Cr layer containing 10-100 ?g/dm2 of Cr is provided.

Abstract: Provided is a liquid crystal polymer film based copper-clad laminate characterized in that a surface of one side or each of both sides of a liquid crystal polymer film has a nitrogen atom content of 10 at % or more, and a metal conductor layer formed by dry plating and/or wet painting is provided on the surface of the liquid crystal polymer film having the nitrogen atom content of 10 at % or more. The liquid crystal polymer film based copper-clad laminate is characterized by having arithmetic average roughness Ra of 0.15 ?m or less and a root-mean-square roughness Rq of 0.20 ?m or less as surface roughness of the liquid crystal polymer film. Also provided is a method for producing a liquid crystal polymer film based copper-clad laminate characterized by performing plasma processing on the surface of the liquid crystal polymer film under a nitrogen atmosphere at a gas pressure of 2.6 to 15 Pa, followed by forming the metal conductor layer by dry plating and/or wet plating.

Abstract: A two-layered copper-clad laminate material, in which one surface or both surfaces of a polyimide film having a thickness of 12.5 to 50 ?m is subjected to a modification treatment by means of a glow discharge plasma treatment in an oxygen gas atmosphere, and a copper layer having a thickness of 1 to 5 ?m is formed by means of sputtering or electroplating on one surface or both surfaces of the polyimide film after the modification treatment; characterized in that the integrated intensity ratio of a C1S peak at 287 to 290 eV to a C1S peak at 283 to 287 eV, obtained by analyzing the photoelectron spectroscopy (XPS) spectra of the surface of the polyimide film after the plasma treatment, is within the range of 0.03 to 0.11.

Abstract: A method for forming a circuit on a flexible laminate substrate, wherein when a circuit is formed using an adhesive-free flexible laminate having a polyimide film that serves as a flexible laminate substrate at least one surface of which is plasma-treated, a tie-coat layer A formed on the polyimide film, a metal conductor layer B formed on the tie-coat layer, and a nickel-copper alloy layer as an alloy layer C on the metal conductor layer, a photoresist is applied on the alloy layer C formed on the metal conductor layer, the photoresist is exposed and developed, the sputter layer C, the metal conductor layer B, and the alloy layer C are removed by etching using the same etching solution so as to retain a circuit portion, and the photoresist of the circuit portion is further removed so as to form the circuit.

Abstract: Provided is a copper-clad laminate comprising a metal conductor layer formed by dry plating and/or wet plating on a surface obtained by subjecting a surface of a liquid crystal polymer film to plasma treatment in an oxygen atmosphere or a nitrogen atmosphere at a gas pressure of 2.6 to 15 Pa. Further provided is a copper-clad laminate comprising a liquid crystal polymer film having a surface roughness after the plasma treatment of 0.15 ?m or less in terms of arithmetic mean roughness Ra and 0.20 ?m or less in terms of root-mean-square roughness Rq. Further provided is a method for manufacturing a copper-clad laminate, wherein a metal conductor layer is formed by dry plating and/or wet plating after subjecting a surface of a liquid crystal polymer film to plasma treatment in an oxygen atmosphere or a nitrogen atmosphere at a gas pressure of 2.6 to 15 Pa.

Abstract: The present invention provides a carrier-attached copper foil, wherein an ultrathin copper foil is not peeled from the carrier prior to the lamination to an insulating substrate, but can be peeled from the carrier after the lamination to the insulating substrate. A carrier-attached copper foil comprising a copper foil carrier, an intermediate layer laminated on the copper foil carrier, and an ultrathin copper layer laminated on the intermediate layer, wherein the intermediate foil is configured with a Ni layer in contact with an interface of the copper foil carrier and a Cr layer in contact with an interface of the ultrathin copper layer, said Ni layer containing 1,000-40,000 ?g/dm2 of Ni and said Cr layer containing 10-100 ?g/dm2 of Cr is provided.

Abstract: Disclosed is a method of forming a circuit on a flexible laminate substrate. When forming a circuit using an adhesiveless flexible laminate which includes a polyimide film as the flexible laminate substrate in which at least one surface thereof is subject to plasma treatment, a tie-coat layer A formed on the polyimide film, a metal conductor layer B formed on the tie-coat layer, and a layer C which has the same components as the tie-coat layer that was formed on the metal conductor layer, the following method is used. The photoresist is coated on the layer C which has the same components as the tie-coat layer that was formed on the metal conductor layer, the photoresist is exposed and developed, the layer C other than the circuit forming parts thereof is selectively removed in advance via pre-etching, the conductor layer B is thereafter removed by supplemental etching with leaving the circuit portion, and the photoresist of the circuit portion is further removed so as to form the circuit.

Abstract: A transmission for a vehicle in which changing a shift position is achieved by sliding a shifter. In sliding the shifter to change the established condition of gear trains respectively corresponding to a plurality of shift positions, the transmission of power from an engine to a main shaft is cut off. A feed mechanism for sliding the shifter is configured to reduce the sliding speed of the shifter in a neutral condition, or to cause the sliding operation of the shifter to have a single stopping action in the neutral condition during the sliding operation of the shifter in changing the established condition of the gear trains. The resulting configuration reduces the engagement noise when changing the shift position.

Abstract: An automatic transmission assembly having a transmission unit including a plurality of gear pairs, a shift drum, a pair of clutches; and a controller. The controller performs a preliminary upshifting action in advance for angularly moving the shift drum depending on a next gear position in an upshifting direction while rotary drive power is being maintained at a given gear position, and when an upshifting command is output, the controller engages one of the clutches simultaneously with the command. When a downshifting command is output, the controller performs a preliminary downshifting action in advance based on the downshifting command. The partially neutral positions are provided between predetermined angular positions on the shift drum for temporarily reducing the angular speed of the shift drum when the shift drum is being angularly rotated.

Abstract: A transmission for a vehicle in which changing a shift position is achieved by sliding a shifter. In sliding the shifter to change the established condition of gear trains respectively corresponding to a plurality of shift positions, the transmission of power from an engine to a main shaft is cut off. A feed mechanism for sliding the shifter is configured to reduce the sliding speed of the shifter or to once stop the sliding operation of the shifter in a neutral condition during the sliding operation of the shifter in changing the established condition of the gear trains. The resulting configuration reduces the engagement noise when changing the shift position.

Abstract: Embodiments of the invention enhance the starting performance of an engine from an automatic stoppage state, in a vehicle with an automatic engine stopping and starting system mounted thereon. In an embodiment, an engine start judging unit detects the presence or absence of a vehicle starting operation on the basis of the status of a throttle switch in an automatic stoppage state of an engine, and, when the seating of the driver is confirmed based on the status of a seat switch, the engine is started. A basic injection amount calculating unit calculates a basic fuel injection amount Ti on the basis of engine parameters such as the engine cooling water temperature TW and the engine speed Ne. An injection amount increasing unit performs a control to increase the fuel injection amount at the time of starting the engine from the automatic stoppage state of the engine, based on the throttle opening detected by a throttle sensor.

Abstract: Embodiments of the invention enhance the starting performance of an engine from an automatic stoppage state, in a vehicle with an automatic engine stopping and starting system mounted thereon. In an embodiment, an engine start judging unit detects the presence or absence of a vehicle starting operation on the basis of the status of a throttle switch in an automatic stoppage state of an engine, and, when the seating of the driver is confirmed based on the status of a seat switch, the engine is started. A basic injection amount calculating unit calculates a basic fuel injection amount Ti on the basis of engine parameters such as the engine cooling water temperature TW and the engine speed Ne. An injection amount increasing unit performs a control to increase the fuel injection amount at the time of starting the engine from the automatic stoppage state of the engine, based on the throttle opening detected by a throttle sensor.

Abstract: To establish a technique of further improving the oxidation resistance of the glossy surface of a copper foil that has a composite layer containing chromium, zinc, and phosphorus on its glossy surface is achieved by a copper foil having excellent oxidation resistance characterized by a composite layer containing chromium, zinc, phosphorus, and nickel formed on the glossy surface of the foil and also to a method of manufacturing the same by electrolysis.

Abstract: A ferroelectric liquid crystal device having a pair of substrates each provided with voltage applying means, an orientation control layer formed on at least one of the substrates, and a layer of ferroelectric liquid crystal composition disposed between the pair of substrates, the ferroelectric liquid crystal composition comprising at least one compound (a) having an optically active group of the formula (I): ##STR1## at least one compound (b) which is reverse to the compound (a) in the direction of a helical pitch induced in a nematic phase and at least one liquid crystal compound (c) exhibiting a smectic C phase, the liquid crystal composition exhibiting at least a smectic C phase, smectic A phase and nematic phase.

Abstract: There is disclosed a treating process whereby the thermal oxidation resistance on the shiny side of a copper foil is enhanced so that the shiny side will not discolor on heating to higher temperatures than usual, without impairing the foil's solder wettability, adhesion to resist, and other properties. A Zn-Ni alloy layer which comprises 50-97 wt % Zn and 3-50 wt % Ni or a Zn-Co alloy layer which comprises 50-97 wt % Zn and 3-50 wt % Co is formed on the shiny side of a copper foil at a deposition quantity of 100-500 .mu.g/dm.sup.2 and then the alloy surface is treated for Cr-base corrosion-preventive coating. The Cr-base corrosion-preventive treatment comprises (1) a treatment for forming a coating film of chromium oxide alone, (2) a treatment for forming a mixed coating film of chromium oxide and zinc and/or zinc oxide or (1)+(2). The roughened side of the copper foil may be treated to form thereon a layer of single metal or alloy of two or more metals chosen from among Cu, Cr, Ni, Fe, Co, and Zn.

Abstract: A developer for developing latent electrostatic images to visible images composed of a magnetic resin carrier composed of magnetic resin particles, each of the magnetic resin particles containing a binder resin and finely-divided magnetic particles dispersed in the binder resin; a magnetic powder carrier consisting essentially of magnetic particles; and an abrasive-type toner composed of toner particles, each of the toner particles containing a toner basic particle and finely-divided particles of an abrasive substance which are fixed on the surface of the toner basic particle. In addition, a method of forming images by use of the above-mentioned developer is disclosed.