Patents by Inventor Kazuhiro Takumi

Kazuhiro Takumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • L-amino acid-producing bacterium and a method for producing an L-amino acid
    Patent number: 9458206
    Abstract: A bacterium belonging to the family Enterobacteriaceae, which has an ability to produce an amino acid such as L-cysteine and has been modified to have specific mutation in the yeas gene, is cultured in a medium, and the L-amino acid is collected from the medium.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: October 4, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Kazuhiro Takumi, Gen Nonaka
  • Method for producing L-cysteine
    Patent number: 9234223
    Abstract: A method for producing L-cysteine and the like is provided by developing a novel technique for improving bacterial L-cysteine-producing ability. The method includes the steps of culturing a bacterium belonging to the genus Escherichia which has L-cysteine-producing ability, and in which expression of a gene involved in sulfite reduction is enhanced, in a medium containing thiosulfate, and collecting L-cysteine, a related substance thereof, or a mixture thereof which accumulate in the medium.
    Type: Grant
    Filed: March 27, 2012
    Date of Patent: January 12, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Shunsuke Yamazaki, Gen Nonaka, Kazuhiro Takumi
  • Method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family
    Patent number: 8852897
    Abstract: A method for producing an L-amino acid is described using a bacterium of the Enterobacteriaceae family, wherein the bacterium contains a protein which is able to confer resistance to growth inhibition by L-cysteine.
    Type: Grant
    Filed: May 3, 2013
    Date of Patent: October 7, 2014
    Assignee: Ajinomoto Co., Inc.
    Inventors: Ekaterina Alekseevna Savrasova, Natalia Viktorovna Stoynova, Gen Nonaka, Shunsuke Yamazaki, Kazuhiro Takumi
  • Method for producing an L-amino acid using a bacterium of the family
    Patent number: 8460903
    Abstract: A method for producing an L-amino acid is described using a bacterium of the Enterobacteriaceae family, wherein the bacterium contains a protein which is able to confer resistance to growth inhibition by L-cysteine.
    Type: Grant
    Filed: January 11, 2011
    Date of Patent: June 11, 2013
    Assignee: Ajinomoto Co., Inc.
    Inventors: Ekaterina Alekseevna Savrasova, Natalia Viktorovna Stoynova, Gen Nonaka, Shunsuke Yamazaki, Kazuhiro Takumi
  • L-cysteine producing bacterium and a method for producing L-cysteine
    Patent number: 8383372
    Abstract: The present invention describes a bacterium belonging to the family Enterobacteriaceae which has L-cysteine-producing ability and has been modified to decrease the activity of a protein encoded by the d0191 gene. This bacterium is cultured in a medium, and L-cysteine, L-cystine, derivatives thereof, or a mixture thereof is collected from the medium.
    Type: Grant
    Filed: March 4, 2009
    Date of Patent: February 26, 2013
    Assignee: Ajinomoto Co., Inc.
    Inventors: Gen Nonaka, Kazuhiro Takumi
  • METHOD FOR PRODUCING L-CYSTEINE
    Publication number: 20120252076
    Abstract: A method for producing L-cysteine and the like is provided by developing a novel technique for improving bacterial L-cysteine-producing ability. The method includes the steps of culturing a bacterium belonging to the genus Escherichia which has L-cysteine-producing ability, and in which expression of a gene involved in sulfite reduction is enhanced, in a medium containing thiosulfate, and collecting L-cysteine, a related substance thereof, or a mixture thereof which accumulate in the medium.
    Type: Application
    Filed: March 27, 2012
    Publication date: October 4, 2012
    Inventors: Shunsuke Yamazaki, Gen Nonaka, Kazuhiro Takumi
  • L-amino acid-producing microorganism and a method for producing an L-amino acid
    Patent number: 8206954
    Abstract: An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae, which has an L-amino acid-producing ability and inherently has a native activity of a glucose dehydrogenase that uses pyrroloquinoline quinone as a coenzyme, but has been modified so that the activity of the glucose dehydrogenase is reduced, in a medium, and collecting the L-amino acid from the medium.
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: June 26, 2012
    Assignee: Ajinomoto Co., Inc.
    Inventors: Rie Takikawa, Yoshihiko Hara, Gen Nonaka, Kazuhiro Takumi
  • L-AMINO ACID-PRODUCING MICROORGANISM AND A METHOD FOR PRODUCING AN L-AMINO ACID
    Publication number: 20110212496
    Abstract: An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae, which has an L-amino acid-producing ability and inherently has a native activity of a glucose dehydrogenase that uses pyrroloquinoline quinone as a coenzyme, but has been modified so that the activity of the glucose dehydrogenase is reduced, in a medium, and collecting the L-amino acid from the medium.
    Type: Application
    Filed: March 1, 2011
    Publication date: September 1, 2011
    Inventors: Rie Takikawa, Yoshihiko Hara, Gen Nonaka, Kazuhiro Takumi
  • L-cysteine-producing bacterium and a method for producing L-cysteine
    Patent number: 8008048
    Abstract: The present invention provides a bacterium belonging to the family Enterobacteriaceae which has L-cysteine-producing ability and has been modified to decrease the activity of the protein encoded by the yhaM gene. This bacterium is cultured in a medium, and L-cysteine, L-cystine, their derivatives, or a mixture thereof is collected from the medium.
    Type: Grant
    Filed: March 4, 2009
    Date of Patent: August 30, 2011
    Assignee: Ajinomoto Co., Inc.
    Inventors: Gen Nonaka, Kazuhiro Takumi
  • METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY
    Publication number: 20110177566
    Abstract: A method for producing an L-amino acid is described using a bacterium of the Enterobacteriaceae family, wherein the bacterium contains a protein which is able to confer resistance to growth inhibition by L-cysteine.
    Type: Application
    Filed: January 11, 2011
    Publication date: July 21, 2011
    Inventors: Ekaterina Alekseevna Savrasova, Natalia Viktorovna Stoynova, Gen Nonaka, Shunsuke Yamazaki, Kazuhiro Takumi
  • L-AMINO ACID-PRODUCING BACTERIUM AND A METHOD FOR PRODUCING AN L-AMINO ACID
    Publication number: 20100209977
    Abstract: A bacterium belonging to the family Enterobacteriaceae, which has an ability to produce an amino acid such as L-cysteine and has been modified to have specific mutation in the yeas gene, is cultured in a medium, and the L-amino acid is collected from the medium.
    Type: Application
    Filed: February 16, 2010
    Publication date: August 19, 2010
    Inventors: Kazuhiro Takumi, Gen Nonaka
  • L-CYSTEINE PRODUCING BACTERIUM AND A METHOD FOR PRODUCING L-CYSTEINE
    Publication number: 20090226984
    Abstract: The present invention describes a bacterium belonging to the family Enterobacteriaceae which has L-cysteine-producing ability and has been modified to decrease the activity of a protein encoded by the d0191 gene. This bacterium is cultured in a medium, and L-cysteine, L-cystine, derivatives thereof, or a mixture thereof is collected from the medium.
    Type: Application
    Filed: March 4, 2009
    Publication date: September 10, 2009
    Inventors: Gen Nonaka, Kazuhiro Takumi
  • L-CYSTEINE-PRODUCING BACTERIUM AND A METHOD FOR PRODUCING L-CYSTEINE
    Publication number: 20090226983
    Abstract: The present invention provides a bacterium belonging to the family Enterobacteriaceae which has L-cysteine-producing ability and has been modified to decrease the activity of the protein encoded by the yhaM gene. This bacterium is cultured in a medium, and L-cysteine, L-cystine, their derivatives, or a mixture thereof is collected from the medium.
    Type: Application
    Filed: March 4, 2009
    Publication date: September 10, 2009
    Inventors: Gen Nonaka, Kazuhiro Takumi