Patents by Inventor Kazuhisa Uchida
Kazuhisa Uchida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7214775Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecules, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having promoted activity.Type: GrantFiled: May 11, 2005Date of Patent: May 8, 2007Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
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Publication number: 20070010009Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: ApplicationFiled: April 13, 2006Publication date: January 11, 2007Applicant: KYOWA HAKKO KOGYO CO., LTDInventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Patent number: 7064191Abstract: The present invention relates to a process for purifying an antibody having a desired property, which comprises using a substance having an affinity to a carbohydrate binding to the antibody; a medicament comprising, as an active ingredient, the antibody purified by the process; and a method for diagnosing or preventing various diseases, which comprises using a substance having an affinity to a carbohydrate binding to an antibody.Type: GrantFiled: October 4, 2001Date of Patent: June 20, 2006Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Toyohide Shinkawa, Kazuhisa Uchida, Motoo Yamasaki, Emi Hosaka, Kenya Shitara
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Publication number: 20060078990Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: ApplicationFiled: November 28, 2005Publication date: April 13, 2006Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Publication number: 20060078991Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: ApplicationFiled: November 28, 2005Publication date: April 13, 2006Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Publication number: 20060064781Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: ApplicationFiled: October 3, 2005Publication date: March 23, 2006Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Publication number: 20060063254Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: ApplicationFiled: September 6, 2005Publication date: March 23, 2006Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Publication number: 20060024800Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.Type: ApplicationFiled: May 11, 2005Publication date: February 2, 2006Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
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Publication number: 20050287138Abstract: The present invention provides an antibody composition comprising an antibody molecule which specifically binds to human CC chemokine receptor 4 (CCR4) and has complex type N-glycoside-linked sugar chains in the Fc region, wherein the complex type N-glycoside-linked sugar chains have a structure in which fucose is not bound to N-acetylglucosamine in the reducing end in the sugar chains; a transformant which produces the antibody composition; a process for producing the antibody composition; and a pharmaceutical composition comprising the antibody composition.Type: ApplicationFiled: October 7, 2004Publication date: December 29, 2005Applicant: Kyowa Hakko Kogyo Co., Ltd.Inventors: Shigeru Iida, Mitsuo Satoh, Miho Urakubo, Masako Wakitani, Kazuhisa Uchida, Rinpei Niwa, Kenya Shitara
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Publication number: 20050276805Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecules, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having promoted activity.Type: ApplicationFiled: May 11, 2005Publication date: December 15, 2005Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
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Publication number: 20050272916Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.Type: ApplicationFiled: May 11, 2005Publication date: December 8, 2005Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
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Publication number: 20050262593Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-modulated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: ApplicationFiled: May 18, 2005Publication date: November 24, 2005Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Publication number: 20050226867Abstract: The present invention provides an antibody composition comprising an antibody molecule which specifically binds to human interleukin-5 receptor ? chain and has complex type N-glycoside-linked sugar chains in the Fc region, wherein the complex type N-glycoside-linked sugar chains have a structure in which fucose is not bound to N-acetylglucosamine in the reducing end in the sugar chains; a transformant which produces the antibody composition; a process for producing the antibody composition; and a pharmaceutical composition comprising the antibody composition.Type: ApplicationFiled: October 7, 2004Publication date: October 13, 2005Applicant: Kyowa Hakko Kogyo Co., Ltd.Inventors: Shigeru Iida, Mitsuo Satoh, Miho Urakubo, Masako Wakitani, Kazuhisa Uchida, Rinpei Niwa, Kenya Shitara, Masamichi Koike
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Patent number: 6946292Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: GrantFiled: October 9, 2001Date of Patent: September 20, 2005Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Patent number: 6884419Abstract: The present invention relates to a fusion polypeptide which comprises a polypeptide having G-CSF activity and a polypeptide having TPO activity and DNA which codes for the fusion polypeptide, to a fusion polypeptide in which a polypeptide having G-CSF activity and a polypeptide having TPO activity are fused via a spacer peptide and DNA which codes for the fusion polypeptide and to a polypeptide in which the fusion polypeptide comprising a polypeptide having G-CSF activity and a polypeptide having TPO activity is chemically modified with a polyalkylene glycol derivative. It also relates to an anemia-treating composition containing the fusion polypeptide as an active ingredient.Type: GrantFiled: October 6, 2000Date of Patent: April 26, 2005Assignee: Kyowa Hakko Kogyo, Co., Ltd.Inventors: Haruhiko Yokoi, Yukimasa Shiotsu, Noboru Konishi, Hideharu Anazawa, Tatsuya Tamaoki, Motoo Yamasaki, Yoko Kato, Kazuhisa Uchida, Kinya Yamashita
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Publication number: 20040093621Abstract: The present invention provides an antibody composition which specifically binds to CD20 and comprises an antibody molecule which has complex N-glycoside-linked sugar chains bound to the Fc region; a process for producing the antibody composition; and a medicament comprising the antibody composition.Type: ApplicationFiled: December 24, 2002Publication date: May 13, 2004Applicant: KYOWA HAKKO KOGYO CO., LTDInventors: Kenya Shitara, Mikiko Sakurada, Kazuhisa Uchida, Toyohide Shinkawa, Mitsuo Satoh, Ryosuke Nakano
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Publication number: 20030115614Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: ApplicationFiled: October 9, 2001Publication date: June 19, 2003Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Publication number: 20030023043Abstract: A method for the production of a highly purified protein at a moderate price which can be provided as a medicament is provided, by constructing a system for purifying a protein having its desired property efficiently and in a high yield independent of physicochemical properties inherent in the protein having a desired property such as isoelectric point and hydrophobicity strength.Type: ApplicationFiled: August 30, 2002Publication date: January 30, 2003Inventors: Kazuhisa Uchida, Motoo Yamasaki
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Publication number: 20020164328Abstract: The present invention relates to a process for purifying an antibody having a desired property, which comprises using a substance having an affinity to a carbohydrate binding to the antibody; a medicament comprising, as an active ingredient, the antibody purified by the process; and a method for diagnosing or preventing various diseases, which comprises using a substance having an affinity to a carbohydrate binding to an antibody.Type: ApplicationFiled: October 4, 2001Publication date: November 7, 2002Inventors: Toyohide Shinkawa, Kazuhisa Uchida, Motoo Yamasaki, Emi Hosaka, Kenya Shitara
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Patent number: 5637928Abstract: An on-vehicle sound instrument with a face plate which does not require any switch mounted thereon to improve portability is not started unless the face plate is mounted on an instrument body, and even if any switch in the instrument body is manipulated. The face plate (30) detachably mounted on the instrument body (10) does not have any switch mounted thereon and includes operation keys (320). The instrument body (10) includes a microcomputer (40) for controlling sound signal outputs and adjustments and an input unit (44) formed of switches for inputting various data to the microcomputer (40) through inputs from the operation keys (320). When the face plate (30) is removed from the instrument body (10) and, for example, a power switch is turned on, a start setting device (60) prevents the microcomputer (40) from activating. The start setting device (60) includes two switches (62, 64) which are simultaneously turned on when the face plate (30) is dismounted from the instrument body (10).Type: GrantFiled: January 25, 1995Date of Patent: June 10, 1997Assignee: Shintom Co., LtdInventors: Yukihiro Nakajima, Motoki Nojiri, Kazuhisa Uchida