Patents by Inventor Kazuhisa Uchida

Kazuhisa Uchida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7214775
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecules, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having promoted activity.
    Type: Grant
    Filed: May 11, 2005
    Date of Patent: May 8, 2007
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • Publication number: 20070010009
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: April 13, 2006
    Publication date: January 11, 2007
    Applicant: KYOWA HAKKO KOGYO CO., LTD
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Patent number: 7064191
    Abstract: The present invention relates to a process for purifying an antibody having a desired property, which comprises using a substance having an affinity to a carbohydrate binding to the antibody; a medicament comprising, as an active ingredient, the antibody purified by the process; and a method for diagnosing or preventing various diseases, which comprises using a substance having an affinity to a carbohydrate binding to an antibody.
    Type: Grant
    Filed: October 4, 2001
    Date of Patent: June 20, 2006
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Toyohide Shinkawa, Kazuhisa Uchida, Motoo Yamasaki, Emi Hosaka, Kenya Shitara
  • Publication number: 20060078990
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: November 28, 2005
    Publication date: April 13, 2006
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Publication number: 20060078991
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: November 28, 2005
    Publication date: April 13, 2006
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Publication number: 20060064781
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: October 3, 2005
    Publication date: March 23, 2006
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Publication number: 20060063254
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: September 6, 2005
    Publication date: March 23, 2006
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Publication number: 20060024800
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.
    Type: Application
    Filed: May 11, 2005
    Publication date: February 2, 2006
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • Publication number: 20050287138
    Abstract: The present invention provides an antibody composition comprising an antibody molecule which specifically binds to human CC chemokine receptor 4 (CCR4) and has complex type N-glycoside-linked sugar chains in the Fc region, wherein the complex type N-glycoside-linked sugar chains have a structure in which fucose is not bound to N-acetylglucosamine in the reducing end in the sugar chains; a transformant which produces the antibody composition; a process for producing the antibody composition; and a pharmaceutical composition comprising the antibody composition.
    Type: Application
    Filed: October 7, 2004
    Publication date: December 29, 2005
    Applicant: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Shigeru Iida, Mitsuo Satoh, Miho Urakubo, Masako Wakitani, Kazuhisa Uchida, Rinpei Niwa, Kenya Shitara
  • Publication number: 20050276805
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecules, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having promoted activity.
    Type: Application
    Filed: May 11, 2005
    Publication date: December 15, 2005
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • Publication number: 20050272916
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.
    Type: Application
    Filed: May 11, 2005
    Publication date: December 8, 2005
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • Publication number: 20050262593
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-modulated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: May 18, 2005
    Publication date: November 24, 2005
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Publication number: 20050226867
    Abstract: The present invention provides an antibody composition comprising an antibody molecule which specifically binds to human interleukin-5 receptor ? chain and has complex type N-glycoside-linked sugar chains in the Fc region, wherein the complex type N-glycoside-linked sugar chains have a structure in which fucose is not bound to N-acetylglucosamine in the reducing end in the sugar chains; a transformant which produces the antibody composition; a process for producing the antibody composition; and a pharmaceutical composition comprising the antibody composition.
    Type: Application
    Filed: October 7, 2004
    Publication date: October 13, 2005
    Applicant: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Shigeru Iida, Mitsuo Satoh, Miho Urakubo, Masako Wakitani, Kazuhisa Uchida, Rinpei Niwa, Kenya Shitara, Masamichi Koike
  • Patent number: 6946292
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: September 20, 2005
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Patent number: 6884419
    Abstract: The present invention relates to a fusion polypeptide which comprises a polypeptide having G-CSF activity and a polypeptide having TPO activity and DNA which codes for the fusion polypeptide, to a fusion polypeptide in which a polypeptide having G-CSF activity and a polypeptide having TPO activity are fused via a spacer peptide and DNA which codes for the fusion polypeptide and to a polypeptide in which the fusion polypeptide comprising a polypeptide having G-CSF activity and a polypeptide having TPO activity is chemically modified with a polyalkylene glycol derivative. It also relates to an anemia-treating composition containing the fusion polypeptide as an active ingredient.
    Type: Grant
    Filed: October 6, 2000
    Date of Patent: April 26, 2005
    Assignee: Kyowa Hakko Kogyo, Co., Ltd.
    Inventors: Haruhiko Yokoi, Yukimasa Shiotsu, Noboru Konishi, Hideharu Anazawa, Tatsuya Tamaoki, Motoo Yamasaki, Yoko Kato, Kazuhisa Uchida, Kinya Yamashita
  • Publication number: 20040093621
    Abstract: The present invention provides an antibody composition which specifically binds to CD20 and comprises an antibody molecule which has complex N-glycoside-linked sugar chains bound to the Fc region; a process for producing the antibody composition; and a medicament comprising the antibody composition.
    Type: Application
    Filed: December 24, 2002
    Publication date: May 13, 2004
    Applicant: KYOWA HAKKO KOGYO CO., LTD
    Inventors: Kenya Shitara, Mikiko Sakurada, Kazuhisa Uchida, Toyohide Shinkawa, Mitsuo Satoh, Ryosuke Nakano
  • Publication number: 20030115614
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: October 9, 2001
    Publication date: June 19, 2003
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Publication number: 20030023043
    Abstract: A method for the production of a highly purified protein at a moderate price which can be provided as a medicament is provided, by constructing a system for purifying a protein having its desired property efficiently and in a high yield independent of physicochemical properties inherent in the protein having a desired property such as isoelectric point and hydrophobicity strength.
    Type: Application
    Filed: August 30, 2002
    Publication date: January 30, 2003
    Inventors: Kazuhisa Uchida, Motoo Yamasaki
  • Publication number: 20020164328
    Abstract: The present invention relates to a process for purifying an antibody having a desired property, which comprises using a substance having an affinity to a carbohydrate binding to the antibody; a medicament comprising, as an active ingredient, the antibody purified by the process; and a method for diagnosing or preventing various diseases, which comprises using a substance having an affinity to a carbohydrate binding to an antibody.
    Type: Application
    Filed: October 4, 2001
    Publication date: November 7, 2002
    Inventors: Toyohide Shinkawa, Kazuhisa Uchida, Motoo Yamasaki, Emi Hosaka, Kenya Shitara
  • Patent number: 5637928
    Abstract: An on-vehicle sound instrument with a face plate which does not require any switch mounted thereon to improve portability is not started unless the face plate is mounted on an instrument body, and even if any switch in the instrument body is manipulated. The face plate (30) detachably mounted on the instrument body (10) does not have any switch mounted thereon and includes operation keys (320). The instrument body (10) includes a microcomputer (40) for controlling sound signal outputs and adjustments and an input unit (44) formed of switches for inputting various data to the microcomputer (40) through inputs from the operation keys (320). When the face plate (30) is removed from the instrument body (10) and, for example, a power switch is turned on, a start setting device (60) prevents the microcomputer (40) from activating. The start setting device (60) includes two switches (62, 64) which are simultaneously turned on when the face plate (30) is dismounted from the instrument body (10).
    Type: Grant
    Filed: January 25, 1995
    Date of Patent: June 10, 1997
    Assignee: Shintom Co., Ltd
    Inventors: Yukihiro Nakajima, Motoki Nojiri, Kazuhisa Uchida