Patents by Inventor Kazuhito Rokutan

Kazuhito Rokutan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220257676
    Abstract: [Problem] The purpose of the present invention is to provide a novel technology capable of regulating female hormone secretion. [Solution] Provided is an agent for regulating female hormone secretion, which contains the lactobacillus strain Lactobacillus gasseri strain CP2305 (accession No.: FERM PB-11331), a treated product of said lactobacillus strain, or extracts thereof.
    Type: Application
    Filed: July 17, 2020
    Publication date: August 18, 2022
    Applicants: Asahi Group Holdings, Ltd., Tokushima University
    Inventors: Daisuke SAWADA, Shigeru FUJIWARA, Tomonori SUGAWARA, Kazuhito ROKUTAN, Kensei NISHIDA, Yuki KUWANO
  • Publication number: 20100197765
    Abstract: A method for promoting expression of p53 mRNA and an expression promoting agent for use in the method are provided. The expression of the p53 gene can be promoted by inhibiting the binding between RNA transcribed from exon 1 of the vegf-A gene and mRNA transcribed from the p53 gene. The inhibition of the binding can be achieved by, for example, degrading the RNA transcribed from the exon 1 of the vegf-A gene, inhibiting transcription of RNA from the exon 1 of the vegf-A gene, or binding a nucleic acid that is different from the mRNA transcribed from the p53 gene to the RNA transcribed from the exon 1 of the vegf-A gene.
    Type: Application
    Filed: September 5, 2008
    Publication date: August 5, 2010
    Applicant: THE UNIVERSITY OF TOKUSHIMA
    Inventors: Shigetada Kondo, Kazuhito Rokutan
  • Patent number: 7734422
    Abstract: An oligonucleotide array comprising an array of multiple oligonucleotides with different base sequences fixed onto known and separate positions on a support substrate, wherein said oligonucleotides are biological stress related genes or complementary sequence chains to the said genes, and the said oligonucleotides are classified according to their gene functions, wherein the fixation region on the support substrate is divided into the said classification.
    Type: Grant
    Filed: April 25, 2005
    Date of Patent: June 8, 2010
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Kazuhito Rokutan, Hiroyuki Tomita, Toshiro Saito
  • Publication number: 20080281531
    Abstract: This invention relates to a method for diagnosing whether or not a subject suffers from depression in a simple manner with high accuracy using the peripheral whole blood sample of the subject. Specifically, the present invention relates to a method for diagnosing depression comprising the steps of: measuring expression levels of 18 genes selected from the group consisting of FASLG; CX3CR1, TBX21, ID2, SLAMF7, PRSS23, YWHAQ, TARDBP, ADRB2, PPP1R8, MMAA, SQLE, PDHA1, HAVCR2, RACGAP1, AHNAK, EDG8, and DUSP5, in peripheral blood isolated from a subject; and determining whether or not the subject suffers from depression based on the expression levels of the 18 genes.
    Type: Application
    Filed: March 14, 2008
    Publication date: November 13, 2008
    Inventors: Kazuhito Rokutan, Tetsuro Ohmori, Toshiro Saito, Masayuki Ohta
  • Publication number: 20050282207
    Abstract: This invention relates to a simple method for evaluating stress of a normal healthy subject with high accuracy is provided. In this method, the expression profile of specific genes that serve as stress marker genes is analyzed, and stress of the subject is evaluated based on the analysis results.
    Type: Application
    Filed: June 15, 2005
    Publication date: December 22, 2005
    Inventors: Kazuhito Rokutan, Kyoko Morita, Kumiko Kamihara, Toshiro Saito
  • Publication number: 20050239110
    Abstract: This invention provides a novel method of diagnosing the conditions of depression of a patient in a simple, objective, and accurate manner. In this method, gene expression is analyzed using mRNA of a subject's peripheral blood to evaluate whether or not the subject is afflicted with depression, the type of depression of a subject who had been evaluated as being afflicted with depression is identified, and the conditions of depression are then diagnosed in accordance with the type of depression.
    Type: Application
    Filed: March 29, 2005
    Publication date: October 27, 2005
    Inventors: Kazuhito Rokutan, Tetsuro Ohmori, Kyoko Morita, Masayuki Ohta, Toshiro Saito
  • Publication number: 20050208561
    Abstract: An oligonucleotide array comprising an array of multiple oligonucleotides with different base sequences fixed onto known and separate positions on a support substrate, wherein said oligonucleotides are biological stress related genes or complementary sequence chains to the said genes, and the said oligonucleotides are classified according to their gene functions, wherein the fixation region on the support substrate is divided into the said classification.
    Type: Application
    Filed: April 25, 2005
    Publication date: September 22, 2005
    Inventors: Kazuhito Rokutan, Hiroyuki Tomita, Toshiro Saito
  • Publication number: 20040185474
    Abstract: This invention relates to a method of simply and accurately diagnosing depression by assaying the expression levels of a specific group of genes in a subject's peripheral leukocytes. In this method, the expression level of at least one gene selected from among apoptosis-associated genes, ATPase-associated genes, cell cycle-associated genes, cytokine-associated genes, heat shock protein-associated genes, polymerase-associated genes, GTP-binding protein-associated genes, protein kinase C-associated genes, and mitochondrial cytochrome C oxidase-associated genes is analyzed using mRNA of a subject's peripheral blood, and symptoms of depression in the subject are diagnosed based on the results of such analysis.
    Type: Application
    Filed: December 19, 2003
    Publication date: September 23, 2004
    Inventors: Kazuhito Rokutan, Tetsuro Ohmori, Toshiro Saito, Hiroyuki Tomita, Hirokazu Kato, Masatoshi Narahara
  • Publication number: 20030059791
    Abstract: An oligonucleotide array comprising an array of multiple oligonucleotides with different base sequences fixed onto known and separate positions on a support substrate, wherein said oligonucleotides are biological stress related genes or complementary sequence chains to the said genes, and the said oligonucleotides are classified according to their gene functions, wherein the fixation region on the support substrate is divided into the said classification.
    Type: Application
    Filed: February 27, 2002
    Publication date: March 27, 2003
    Inventors: Kazuhito Rokutan, Hiroyuki Tomita, Toshiro Saito