Patents by Inventor Kazushi Imai

Kazushi Imai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic treatment of chronic obstructive pulmonary disease
    Patent number: 7309578
    Abstract: The present invention provides a method of treating or preventing a chronic obstructive pulmonary disease in a subject, comprising administering to said subject an amount of an agent affective to inhibit apoptosis of the subject's lung cells and thus treat or prevent chronic obstructive pulmonary disease in the subject. The present invention provides for a method of diagnosing the disease.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: December 18, 2007
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Jeanine D'Armiento, Kazushi Imai
  • Method of detecting rheumatoid arthritis by detecting overexpression of wnt
    Publication number: 20050221321
    Abstract: A convenient and highly accurate pre-examination of detecting rheumatoid arthritis wherein at least the upregulation of expression of WNT at least the upregulation of expression of WNT10B and at least the regulated expression of FRP1 in joint synovial liquid, joint synovial tissue or peripheral blood are detected in parallel.
    Type: Application
    Filed: April 25, 2003
    Publication date: October 6, 2005
    Inventor: Kazushi Imai
  • Therapeutic treatment of chronic obstructive pulmonary disease
    Patent number: 6656461
    Abstract: The present invention provides a method of treating or preventing a chronic obstructive pulmonary disease in a subject, comprising administering to said subject an amount of an agent effective to inhibit apoptosis of the subject's lung cells and thus treat or prevent chronic obstructive pulmonary disease in the subject. The present invention provides for a method of identifying a compound effective to treat or prevent a chronic obstructive pulmonary disease, comprising (a) contacting lung cells from a subject having a chronic obstructive pulmonary disease with the compound and measuring the level of apoptosis of the lung cells in the presence of said compound, (b) measuring the level of apoptosis of the lung cells from the same subject in the absence of said compound, (c) comparing the level of apoptosis in step (a) with the level of apoptosis in step (b), wherein a higher level of apoptosis in step (a) indicate that the compound is effective to treat or prevent chronic obstructive pulmonary disease.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: December 2, 2003
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Jeanine D'Armiento, Kazushi Imai
  • Novel therapeutic treatment of chronic obstructive pulmonary disease
    Publication number: 20030215420
    Abstract: The present invention provides a method of treating or preventing a chronic obstructive pulmonary disease in a subject, comprising administering to said subject an amount of an agent affective to inhibit apoptosis of the subject's lung cells and thus treat or prevent chronic obstructive pulmonary disease in the subject. The present invention provides for a method of diagnosing the disease.
    Type: Application
    Filed: May 19, 2003
    Publication date: November 20, 2003
    Inventors: Jeanine D'Armiento, Kazushi Imai