Patents by Inventor Kazuteru Yamada
Kazuteru Yamada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220213492Abstract: Described herein are enzymes, such as for example, methanol dehydrogenase (MDH), 3-hexulose-6-phosphate isomerase (PHI), 3-hexulose-6-phosphate synthase (HPS), ribose-5-phosphate isomerase (RPI), ribulose 5-phosphate 3-epimerase (RPE), transketolase (TKT), transaldolase (TAL) enzymes, phosphofructokinase (PFK), Sedoheptulose 1,7-Bisphosphatase (GLPX), fructose-bisphosphate aldolase (FBA), 6-phosphogluconate dehydrogenase (GND), and glucose-6-phosphate dehydrogenase (ZWF); recombinant host cells expressing the enzymes; methods of producing methylotrophic cells; and methods of producing amino acids (e.g., lysine).Type: ApplicationFiled: April 17, 2020Publication date: July 7, 2022Applicant: Ginkgo Bioworks, Inc.Inventors: Hui Zhou, Massimo Merighi, Micjael G. Napolitano, Kennji Abe, Yoshihiro Ito, Takayuki Asahara, Thomas Perli, Sergio L. Florez, Ryan J. Putman, Ryo Takeshita, Yuri Uehara, Akito Chinen, Kazuteru Yamada
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Patent number: 11198894Abstract: A method for producing an L-amino acid such as L-lysine is provided. An L-amino acid is produced by culturing a bacterium having an L-amino acid-producing ability, which has been modified so that the activity of a carotenoid biosynthesis enzyme is increased, in a medium, and collecting the L-amino acid from the medium.Type: GrantFiled: February 5, 2019Date of Patent: December 14, 2021Assignee: AJINOMOTO CO., INC.Inventors: Kazuteru Yamada, Ye Zhang, Kenji Abe, Naoki Iwanaga, Ryo Takeshita, Yuri Uehara, Chika Hikichi, Yasuhiro Oota
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Patent number: 10941427Abstract: A production system for a product selected from a nitrogen-containing product and a fermented and cultured product that does not involve (or can minimize) the transport of liquid ammonia can include: an ammonia synthesis apparatus in which an ammonia-containing gas is synthesized by reaction of a source gas containing hydrogen and nitrogen in the presence of a supported metal catalyst containing as a support one or more selected from the group consisting of: i) a conductive mayenite compound; ii) a two-dimensional electride compound or a precursor thereof; and iii) a complex formed of a support base containing at least one metal oxide selected from ZrO2, TiO2, CeO2, and MgO and a metal amide represented by a formula M(NH2)x (where M represents one or more selected from Li, Na, K, Be, Mg, Ca, Sr, Ba, and Eu; and x represents a valence number of M) supported by the support base.Type: GrantFiled: August 11, 2017Date of Patent: March 9, 2021Assignees: Ajinomoto Co., Inc., Tokyo Institute of TechnologyInventors: Mitsuhiro Kishino, Hiroyuki Kojima, Hideo Hosono, Michikazu Hara, Masaaki Kitano, Toshiharu Yokoyama, Toru Numaguchi, Munenobu Ito, Kazuteru Yamada, Hiromi Noguchi
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Publication number: 20200407762Abstract: Provided is a novel production system that does not involve, or can minimize, the transport of liquid ammonia in the production of an organic compound or the production of a microorganism by microbial fermentation. A production system for an organic compound or a microorganism includes: an ammonia synthesis apparatus in which an ammonia-containing gas is synthesized by reaction of a source gas containing hydrogen and nitrogen in the presence of a supported ruthenium catalyst; and a culture apparatus that cultures a microorganism having organic compound productivity using ammonia originating from the ammonia-containing gas obtained by using the ammonia synthesis apparatus.Type: ApplicationFiled: September 14, 2020Publication date: December 31, 2020Applicants: AJINOMOTO CO., INC., TOKYO INSTITUTE OF TECHNOLOGYInventors: Mitsuhiro Kishino, Hiroyuki Kojima, Hideo Hosono, Michikazu Hara, Masaaki Kitano, Toshiharu Yokoyama, Toru Numaguchi, Munenobu Ito, Kazuteru Yamada, Hiromi Noguchi
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Patent number: 10808267Abstract: Provided is a novel production system that does not involve, or can minimize, the transport of liquid ammonia in the production of an organic compound or the production of a microorganism by microbial fermentation. A production system for an organic compound or a microorganism includes: an ammonia synthesis apparatus in which an ammonia-containing gas is synthesized by reaction of a source gas containing hydrogen and nitrogen in the presence of a supported ruthenium catalyst; and a culture apparatus that cultures a microorganism having organic compound productivity using ammonia originating from the ammonia-containing gas obtained by using the ammonia synthesis apparatus.Type: GrantFiled: August 11, 2017Date of Patent: October 20, 2020Assignees: Ajinomoto Co., Inc., Tokyo Institute of TechnologyInventors: Mitsuhiro Kishino, Hiroyuki Kojima, Hideo Hosono, Michikazu Hara, Masaaki Kitano, Toshiharu Yokoyama, Toru Numaguchi, Munenobu Ito, Kazuteru Yamada, Hiromi Noguchi
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Publication number: 20190161780Abstract: A method for producing an L-amino acid such as L-lysine is provided. An L-amino acid is produced by culturing a bacterium having an L-amino acid-producing ability, which has been modified so that the activity of a carotenoid biosynthesis enzyme is increased, in a medium, and collecting the L-amino acid from the medium.Type: ApplicationFiled: February 5, 2019Publication date: May 30, 2019Applicant: AJINOMOTO CO., INC.Inventors: Kazuteru Yamada, Ye Zhang, Kenji Abe, Naoki Iwanaga, Ryo Takeshita, Yuri Uehara, Chika Hikichi, Yasuhiro Oota
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Patent number: 10155952Abstract: A method for producing a target substance is provided. A target substance is produced by culturing a coryneform bacterium, which is able to produce a target substance, and which also has an improved ability to assimilate xylose as a result of the introduction of a mutation into a coding region and/or an expression control region of the NCgl2954 gene on the chromosome of the bacterium. The culture is conducted in a medium containing xylose, and the target substance can be collected from the medium.Type: GrantFiled: April 21, 2016Date of Patent: December 18, 2018Assignee: AJINOMOTO CO., INC.Inventors: Kazuteru Yamada, Yoshihiko Hara
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Publication number: 20170342449Abstract: Provided is a novel production system for a product selected from a nitrogen-containing product and a fermented and cultured product that does not involve (or can minimize) the transport of liquid ammonia.Type: ApplicationFiled: August 11, 2017Publication date: November 30, 2017Applicants: AJINOMOTO CO., INC., TOKYO INSTITUTE OF TECHNOLOGYInventors: Mitsuhiro Kishino, Hiroyuki Kojima, Hideo Hosono, Michikazu Hara, Masaaki Kitano, Toshiharu Yokoyama, Toru Numaguchi, Munenobu Ito, Kazuteru Yamada, Hiromi Noguchi
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Publication number: 20170342450Abstract: Provided is a novel production system that does not involve, or can minimize, the transport of liquid ammonia in the production of an organic compound or the production of a microorganism by microbial fermentation. A production system for an organic compound or a microorganism includes: an ammonia synthesis apparatus in which an ammonia-containing gas is synthesized by reaction of a source gas containing hydrogen and nitrogen in the presence of a supported ruthenium catalyst; and a culture apparatus that cultures a microorganism having organic compound productivity using ammonia originating from the ammonia-containing gas obtained by using the ammonia synthesis apparatus.Type: ApplicationFiled: August 11, 2017Publication date: November 30, 2017Applicants: AJINOMOTO CO., INC., TOKYO INSTITUTE OF TECHNOLOGYInventors: Mitsuhiro Kishino, Hiroyuki Kojima, Hideo Hosono, Michikazu Hara, Masaaki Kitano, Toshiharu Yokoyama, Toru Numaguchi, Munenobu Ito, Kazuteru Yamada, Hiromi Noguchi
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Publication number: 20160222394Abstract: A method for producing a target substance is provided. A target substance is produced by culturing a coryneform bacterium, which is able to produce a target substance, and which also has an improved ability to assimilate xylose as a result of the introduction of a mutation into a coding region and/or an expression control region of the NCgl2954 gene on the chromosome of the bacterium. The culture is conducted in a medium containing xylose, and the target substance can be collected from the medium.Type: ApplicationFiled: April 21, 2016Publication date: August 4, 2016Applicant: AJINOMOTO CO., INC.Inventors: Kazuteru Yamada, Yoshihiko Hara
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Patent number: 9045789Abstract: A target substance can be produced by culturing a bacterium having an ability to produce 2-ketoglutaric acid or a derivative thereof, and an ability to produce xylonic acid from xylose, which is imparted with xylonate dehydratase activity, 2-keto-3-deoxyxylonate dehydratase activity and 2-ketoglutaric semialdehyde dehydrogenase activity, or in which these activities are enhanced, in a medium containing xylose as a carbon source to produce and accumulate the target substance in the medium, and collecting the target substance from the medium.Type: GrantFiled: June 11, 2013Date of Patent: June 2, 2015Assignee: AJINOMOTO CO., INC.Inventors: Yousuke Nishio, Youko Yamamoto, Kazuteru Yamada, Kosuke Yokota
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Publication number: 20130295621Abstract: A target substance can be produced by culturing a bacterium having an ability to produce 2-ketoglutaric acid or a derivative thereof, and an ability to produce xylonic acid from xylose, which is imparted with xylonate dehydratase activity, 2-keto-3-deoxyxylonate dehydratase activity and 2-ketoglutaric semialdehyde dehydrogenase activity, or in which these activities are enhanced, in a medium containing xylose as a carbon source to produce and accumulate the target substance in the medium, and collecting the target substance from the medium.Type: ApplicationFiled: June 11, 2013Publication date: November 7, 2013Inventors: Yousuke Nishio, Youko Yamamoto, Kazuteru Yamada, Kosuke Yokota