Patents by Inventor Keiichi TOZAWA
Keiichi TOZAWA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11712451Abstract: An object of the present invention is to provide, for example, a more practical wound healing accelerator that more effectively accelerates wound healing. More specifically, a feature of the present invention is to provide, for example, a more practical wound healing accelerator that is easily obtained in a larger amount than that of peripheral blood platelet and has a better wound healing effect than that of peripheral blood platelet. The present invention employs a platelet-like cell population coexpressing one or more platelet surface markers and one or more mesenchymal cell surface markers. A wound healing accelerator containing the platelet-like cell population is a more practical wound healing accelerator that more effectively accelerates wound healing. The platelet-like cell population is easily obtained in a larger amount than that of peripheral blood platelet and has a better wound healing effect than that of peripheral blood platelet.Type: GrantFiled: October 17, 2018Date of Patent: August 1, 2023Assignee: KEIO UniversityInventors: Yumiko Matsubara, Yasuo Ikeda, Keiichi Tozawa, Yukako Uruga, Masaki Yazawa, Taisuke Mori, Kazuo Kishi
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Patent number: 11518982Abstract: A method for producing a mesenchymal cell line derived from a vertebrate adipose tissue, and a mesenchymal cell line derived from a vertebrate adipose tissue produced by the method. Advantageously, a method for producing a mesenchymal cell line derived from a vertebrate adipose tissue is achieved more simply, in a shorter period of time, and more efficiently. Also, a mesenchymal cell line is derived from a vertebrate adipose tissue produced by the production method. The method for producing a mesenchymal cell line derived from a vertebrate adipose tissue comprises: (A) inducing differentiation of one or more cells selected from a stromal vascular fraction comprising a mesenchymal stem cell, an adipose progenitor cell, and a stromal cell of a vertebrate adipose tissue into a mature adipocyte; and (B) inducing dedifferentiation of the mature adipocyte obtained in step (A) to obtain a mesenchymal cell line derived from the vertebrate adipose tissue.Type: GrantFiled: November 30, 2016Date of Patent: December 6, 2022Assignee: AdipoSeeds, Inc.Inventors: Yumiko Matsubara, Yasuo Ikeda, Keiichi Tozawa, Hideyuki Saya, Hiroyuki Nobusue
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Patent number: 11338488Abstract: A mold clamping device includes a base, a stationary platen fixed to the base and supporting a stationary mold, a movable platen movable on the base and supporting a movable mold, and a mold clamping mechanism for clamping the movable mold against the stationary mold. Tie bars extend from the stationary platen completely through both the movable platen and the mold clamping mechanism. A shaft supporting plate is fixed to the base and has openings through which the tie bars slidably extend for supporting the tie bars. The shaft supporting plate terminates at its lower end portion in two spaced-apart shoes that are fixed to the base. The bottom surface of each shoe has a larger area than the cross-sectional area of the shaft supporting plate situated vertically above the shoe.Type: GrantFiled: December 25, 2020Date of Patent: May 24, 2022Inventors: Hozumi Yoda, Satoshi Hoshino, Hiroo Okubo, Atsushi Murata, Keiichi Tozawa
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Patent number: 11117300Abstract: A mold clamping device includes a base, a stationary platen fixed to the base and supporting a stationary mold, a movable platen movable on the base and supporting a movable mold, and a mold clamping mechanism for clamping the movable mold against the stationary mold. Tie bars extend from the stationary platen completely through both the movable platen and the mold clamping mechanism. A shaft supporting plate is fixed to the ends of the tie bars and terminates at its lower end portion in two spaced-apart shoes that have flat bottom surfaces in direct sliding contact with the base. The flat bottom surface of each shoe has a larger area than the cross-sectional area of the shaft supporting plate situated vertically above the shoe.Type: GrantFiled: March 20, 2020Date of Patent: September 14, 2021Inventors: Hozumi Yoda, Satoshi Hoshino, Hiroo Okubo, Atsushi Murata, Keiichi Tozawa
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Publication number: 20210114273Abstract: A mold clamping device includes a base, a stationary platen, a movable platen, a mold clamping mechanism, a tie bar, and a half nut. This mold clamping device further includes a shaft supporting plate supporting a tip of the tie bar. This shaft supporting plate is fixed to the tip of the tie bar, and is mounted on the base so as to be freely movable.Type: ApplicationFiled: December 25, 2020Publication date: April 22, 2021Inventors: Hozumi YODA, Satoshi HOSHINO, Hiroo OKUBO, Atsushi MURATA, Keiichi TOZAWA
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Publication number: 20200307051Abstract: A mold clamping device includes a base, a stationary platen, a movable platen, a mold clamping mechanism, a tie bar, and a half nut. This mold clamping device further includes a shaft supporting plate supporting a tip of the tie bar. This shaft supporting plate is fixed to the tip of the tie bar, and is mounted on the base so as to be freely movable.Type: ApplicationFiled: March 20, 2020Publication date: October 1, 2020Inventors: Hozumi YODA, Satoshi HOSHINO, Hiroo OKUBO, Atsushi MURATA, Keiichi TOZAWA
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Publication number: 20200190474Abstract: A method for producing a mesenchymal cell line derived from a vertebrate adipose tissue, and a mesenchymal cell line derived from a vertebrate adipose tissue produced by the method. Advantageously, a method for producing a mesenchymal cell line derived from a vertebrate adipose tissue is achieved more simply, in a shorter period of time, and more efficiently. Also, a mesenchymal cell line is derived from a vertebrate adipose tissue produced by the production method. The method for producing a mesenchymal cell line derived from a vertebrate adipose tissue comprises: (A) inducing differentiation of one or more cells selected from a stromal vascular fraction comprising a mesenchymal stem cell, an adipose progenitor cell, and a stromal cell of a vertebrate adipose tissue into a mature adipocyte; and (B) inducing dedifferentiation of the mature adipocyte obtained in step (A) to obtain a mesenchymal cell line derived from the vertebrate adipose tissue.Type: ApplicationFiled: November 30, 2016Publication date: June 18, 2020Inventors: Yumiko MATSUBARA, Yasuo IKEDA, Keiichi TOZAWA, Hideyuki SAYA, Hiroyuki NOBUSUE
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Patent number: 10493679Abstract: When a plurality of sets of molds, spaced a predetermined distance along a circumferential direction of a rotary platen, are attached through predetermined clamp portions to a mold attachment surface of the rotary platen supported by a movable platen included in a mold clamping device and a mold attachment surface of a fixed platen opposite this mold attachment surface, at least a mold clamping force, when the mold is attached, is previously limited to a limited mold clamping force lower than a mold clamping force at the time of molding. A mold attaching mode is set that has an interlock function of preventing the limitation from being cancelled until a condition under which all the clamp portions are turned on is satisfied. The selected mold attaching mode is performed when the molds are attached and the plurality of sets of molds are sequentially attached set by set.Type: GrantFiled: April 16, 2015Date of Patent: December 3, 2019Assignee: NISSEI PLASTIC INDUSTRIAL CO., LTD.Inventor: Keiichi Tozawa
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Publication number: 20190269732Abstract: An object of the present invention is to provide, for example, a more practical wound healing accelerator that more effectively accelerates wound healing. More specifically, a feature of the present invention is to provide, for example, a more practical wound healing accelerator that is easily obtained in a larger amount than that of peripheral blood platelet and has a better wound healing effect than that of peripheral blood platelet. The present invention employs a platelet-like cell population coexpressing one or more platelet surface markers and one or more mesenchymal cell surface markers. A wound healing accelerator containing the platelet-like cell population is a more practical wound healing accelerator that more effectively accelerates wound healing. The platelet-like cell population is easily obtained in a larger amount than that of peripheral blood platelet and has a better wound healing effect than that of peripheral blood platelet.Type: ApplicationFiled: October 17, 2018Publication date: September 5, 2019Inventors: Yumiko MATSUBARA, Yasuo IKEDA, Keiichi TOZAWA, Yukako URUGA, Masaki YAZAWA, Taisuke MORI, Kazuo KISHI
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Patent number: 10112332Abstract: When a heating device is formed which includes at least one or more heaters 4n, 4a, 4b, 4c and 4d that are provided on the outer circumferential surfaces 2f and 3f of at least one of a heating cylinder 2 and an injection nozzle 3 to heat at least one of the heating cylinder 2 and the injection nozzle 3, at least some heaters 4a, 4b, 4c, . . . of all the heaters 4n, 4a, . . . are formed with air cooling-capable heaters 4as, 4bs and 4cs in which a panel member 5 formed of a material R having thermal conductivity is interposed between the heaters 4a, 4b, 4c, . . . and the outer circumferential surfaces 2f and 3f of at least one of the heating cylinder 2 and the injection nozzle 3, in which an air path 6 for air cooling is formed in the panel member 5 and in which an air outlet and inlet portion 8 allowing air A to be passed from an air supply portion 7 is provided in the air path 6.Type: GrantFiled: October 26, 2015Date of Patent: October 30, 2018Assignee: NISSEI PLASTIC INDUSTRIAL CO., LTD.Inventors: Yuichi Sakurada, Toshimi Kato, Keiichi Tozawa
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Publication number: 20160114511Abstract: When a heating device is formed which includes at least one or more heaters 4n, 4a, 4b, 4c and 4d that are provided on the outer circumferential surfaces 2f and 3f of at least one of a heating cylinder 2 and an injection nozzle 3 to heat at least one of the heating cylinder 2 and the injection nozzle 3, at least some heaters 4a, 4b, 4c, . . . of all the heaters 4n, 4a, . . . are formed with air cooling-capable heaters 4as, 4bs and 4cs in which a panel member 5 formed of a material R having thermal conductivity is interposed between the heaters 4a, 4b, 4c, . . . and the outer circumferential surfaces 2f and 3f of at least one of the heating cylinder 2 and the injection nozzle 3, in which an air path 6 for air cooling is formed in the panel member 5 and in which an air outlet and inlet portion 8 allowing air A to be passed from an air supply portion 7 is provided in the air path 6.Type: ApplicationFiled: October 26, 2015Publication date: April 28, 2016Applicant: NISSEI PLASTIC INDUSTRIAL CO., LTD.Inventors: Yuichi SAKURADA, Toshimi KATO, Keiichi TOZAWA
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Publication number: 20150298376Abstract: When a plurality of sets of molds, spaced a predetermined distance along a circumferential direction of a rotary platen, are attached through predetermined clamp portions to a mold attachment surface of the rotary platen supported by a movable platen included in a mold clamping device and a mold attachment surface of a fixed platen opposite this mold attachment surface, at least a mold clamping force, when the mold is attached, is previously limited to a limited mold clamping force lower than a mold clamping force at the time of molding. A mold attaching mode is set that has an interlock function of preventing the limitation from being cancelled until a condition under which all the clamp portions are turned on is satisfied. The selected mold attaching mode is performed when the molds are attached and the plurality of sets of molds are sequentially attached set by set.Type: ApplicationFiled: April 16, 2015Publication date: October 22, 2015Applicant: NISSEI PLASTIC INDUSTRIAL CO., LTD.Inventor: Keiichi TOZAWA