Patents by Inventor Keith Graham

Keith Graham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9366552
    Abstract: A sensor assembly for use in downhole deployment is disclosed. The assembly has a cylindrical housing having a hollow interior and a cartridge sub-assembly housed in the cylindrical housing. The cartridge sub-assembly has a sensor element, a first printed circuit board (PCB) securing the sensor element in a holding position, and a first potting sealing the first PCB and the sensor element in the holding position. The cartridge sub-assembly is secured in the hollow interior by a second potting. Additionally, a method of manufacturing the sensor assembly and an array of sensor assemblies are disclosed.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: June 14, 2016
    Assignee: Egs Solutions Inc.
    Inventors: Alex Baranov, Wade Coulter, Keith Graham, Chris Hawryluck
  • Publication number: 20160159789
    Abstract: The present invention relates to substituted pyrazolopyridine compounds of general formula I as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: July 4, 2014
    Publication date: June 9, 2016
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Ulrich Klar, Lars Wortmann, Georg Kettschau, Keith Graham, Anja Richter, Philip Lienau, Florian Puehler, Kirstin Petersen, Franziska Siegel, Detlev Sulzle
  • Patent number: 9332767
    Abstract: A microwaveable cookable or reheatable foodstuff coating composition comprising an aqueous mixture including: a) starch b) a flour component comprising gluten free flour and maize flour c) a gelling agent d) an enzyme additive comprising alpha amylase; and e) optional further ingredients.
    Type: Grant
    Filed: September 20, 2013
    Date of Patent: May 10, 2016
    Assignee: Crisp Sensation Holding S.A.
    Inventor: Keith Graham Pickford
  • Patent number: 9326537
    Abstract: A frozen, microwaveable, coated food product comprising: a core of cooked edible material having a weight equal to 15-95 wt. % of the food product; a fried coating that envelops the core of edible material and has a weight equal to 5-85 wt. % of the total weight of the food product, said coating comprising at least three coating layers, including an inner crumb layer, an outer crumb layer and a batter layer that separates the inner crumb layer from the outer crumb layer; wherein both the inner crumb layer and the outer crumb layer comprise a milled farinaceous dough extrudate containing 0.05-5 wt. % of added hydrocolloid.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: May 3, 2016
    Assignee: Crisp Sensation Holding S.A.
    Inventor: Keith Graham Pickford
  • Patent number: 9326536
    Abstract: A method of producing a frozen, microwaveable, coated food product, said method comprising the steps of: providing a portion of a solid or solidified substrate; coating the portion with an aqueous precoating liquid to form a precoated portion; applying a coating of bonding crumb to the precoated portion to form a crumb coated portion; applying a batter to the crumb coated portion to form a batter coated portion; applying a coating of coating crumb to the batter coated portion to form a breaded portion; frying the breaded portion by contacting said breaded portion for at least 100 seconds with hot oil having a temperature of at least 150° C., thereby producing a fried coated portion having a core temperature in excess of 70° C.; and freezing the fried coated portion by introducing said fried portion into a freezer; wherein the core temperature of the fried coated portion is not less than 50° C., preferably not less than 60° C.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: May 3, 2016
    Assignee: Crisp Sensation Holding S.A.
    Inventor: Keith Graham Pickford
  • Publication number: 20160106127
    Abstract: A crumb is manufactured by a process including adding an aqueous flour mixture into an extruder, partially extruding the aqueous mixture through the extruder, adding an aqueous gelling agent to the extruder at a point downstream of the start of the extrusion of the aqueous mixture through the extruder to form a resultant mixture of the aqueous mixture and the aqueous gelling agent in the extruder, and extruding the resultant mixture at a temperature greater than 100° C. to form an extrudate. The extrudate is allowed to expand, dried and milled to form the crumb, which has moisture-resistant properties particularly well-suited for use on frozen, microwavable food products.
    Type: Application
    Filed: June 12, 2015
    Publication date: April 21, 2016
    Applicant: CRISP SENSATION HOLDING S.A.
    Inventor: KEITH GRAHAM PICKFORD
  • Patent number: 9308282
    Abstract: What is described are the compounds and the synthesis of [F-18]-labelled L-glutamic acid, [F-18]-labelled L-glutamate, their derivatives of the formula (I) and their use.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: April 12, 2016
    Assignee: PIRAMAL IMAGING SA
    Inventors: Matthias Friebe, Heribert Schmitt-Willich, Matthias Berndt, Ludger Dinkelborg, Norman Koglin, Keith Graham
  • Patent number: 9295272
    Abstract: A method of manufacturing a crumb coated food product is disclosed. The method includes the steps of forming an aqueous mixture including a flour mixture having one or more flours; sodium bicarbonate; optional additives selected from processing aids, salts, colorants and, water; adding the mixture into an extruder; adding an aqueous gelling agent to the extruder; extruding the resultant mixture at a temperature greater than 100° C. to form an extrudate; allowing the extrudate to expand to form a porous product; drying the product, and milling the dried product to form a crumb.
    Type: Grant
    Filed: July 29, 2013
    Date of Patent: March 29, 2016
    Assignee: Crisp Sensation Holding S.A.
    Inventor: Keith Graham Pickford
  • Publication number: 20160060209
    Abstract: The present invention describes a new class of trinuclear hafnium complexes comprising two hexadentate azainositol carboxylic acid ligands, methods for their preparation and their use as X-ray contrast agents and X-ray diagnostic agents. The claimed compounds can be described by the following Markush formula describing rinuclear hafnium complexes of general formula (I). The following is a compound according to the above Markush formula (example 8).
    Type: Application
    Filed: April 22, 2014
    Publication date: March 3, 2016
    Inventors: MARKUS BERGER, DETLEV SÜLZLE, THOMAS FRENZEL, III, KEITH GRAHAM, GREGOR JOST, CHRISTIAN NEIS, KASPAR HEGETSCHWEILER, HUBERTUS PIETSCH
  • Publication number: 20160017843
    Abstract: A thermodynamic machine (1) of a Stirling type, the machine comprising an expansion chamber (5), a compression in chamber (6), a regenerator (12) disposed between the expansion and compression chambers; a first heat exchanger (13) in communication with the expansion chamber and the regenerator; a second heat exchanger (14) in communication with the compression chamber and the regenerator; a first bypass conduit (15) connecting the expansion chamber with the regenerator bypassing the first heat exchanger; a second bypass conduit (16) connecting the compression chamber with the regenerator bypassing the second heat exchanger; at least a pair valves (18, 20, 22, 24), one valve (18, 20) provided between the expansion chamber and the first heat exchanger and/or between the regenerator and the first heat exchanger and/or in the first bypass conduit between the expansion chamber and the regenerator; and the other valve (22, 24) provided between the compression chamber and the second heat exchanger and/or between the
    Type: Application
    Filed: March 7, 2014
    Publication date: January 21, 2016
    Inventors: Kenneth Whittaker, Keith Graham Watt
  • Patent number: 9238631
    Abstract: This invention relates to novel compounds suitable for labeling by 18F and to the corresponding 18F labeled compounds themselves, 19F-fluorinated analogs thereof and their use as reference standards, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging by Positron Emission Tomography (PET).
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: January 19, 2016
    Assignee: PIRAMAL IMAGING SA
    Inventors: Mathias Berndt, Andre Muller, Heribert Schmitt-Willich, Timo Stellfeld, Georg Kettschau, Thomas Brumby, Keith Graham, Lutz Lehmann, Jorma Haβfeld, Martin Kruger
  • Publication number: 20160009734
    Abstract: The present invention relates to substituted thiazolopyrimidine compounds of general formula I as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: March 6, 2014
    Publication date: January 14, 2016
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Ulrich KLAR, Lars WORTMANN, Keith GRAHAM, Florian PUEHLER, Detlev SÜLZLE, Georg KETTSCHAU, Philip LIENAU
  • Publication number: 20150252047
    Abstract: The present invention relates to substituted indazol-pyrrolopyrimidine compounds of general formula (I): in which R1a, R1b, R1c, R1d, R2a and R2b are as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: September 23, 2013
    Publication date: September 10, 2015
    Inventors: Ulrich Klar, Lars Wortmann, Georg Kettschau, Florian Puehler, Philip Lienau, Kirstin Petersen, Andrea Hägebarth, Detlev Sülzle, Keith Graham, Anja Richter
  • Publication number: 20150218173
    Abstract: The present invention relates to substituted indazol-pyrrolopyrimidine compounds of general formula I: in which R1a, R1b, R1c, R1d, R2a are as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: September 24, 2013
    Publication date: August 6, 2015
    Inventors: Lars Wortmann, Ulrich Klar, Georg Kettschau, Florian Puehler, Philip Lienau, Kirstin Petersen, Andrea Hägebarth, Detlev Sülzle, Keith Graham, Anja Richter
  • Patent number: 9085812
    Abstract: The present invention discloses a new process for leaching sulfide minerals consisting of leaching crushed ore in a vat reactor, wherein the leaching solution is fed with an ORP value close to the upper limit suitable for leaching and the exiting leaching solution leaves the reactor with an ORP above the lower limit suitable for leaching the ore. The output leaching solution that leaves the leaching reactor goes through an iron oxidation stage outside the leaching reactor, with the iron oxidation producing soluble ferric sulfate that is mixed with a recirculated portion of the output leaching solution to increase its ORP up to a value close to the upper limit of the redox potential range that is suitable for the ore leaching.
    Type: Grant
    Filed: May 3, 2013
    Date of Patent: July 21, 2015
    Assignee: VALE S.A.
    Inventors: Chris Andre Du Plessis, Nelson Eduardo Mora-Huertas, Felipe Hilario Guimaraes, Keith Graham Bowes
  • Publication number: 20150147440
    Abstract: A method of producing a frozen microwaveable, coated food product, involves providing pieces of mozzarella cheese, the pieces having a maximum dimension of 1 cm, mixing the pieces of cheese with a stabilizing composition, mixing to form a homogenous cheese dough, forming the dough into portions, freezing the portions and maintaining the frozen portions for at least eight hours, applying a pre-coating to the frozen portions to produce pre-coated portions, applying a batter coating to the pre-coated portions to produce batter coated portions, applying one or more layers of crumb to the batter coated portions to provide a crumb coated portion, frying the crumb coated portions to produce fried portions, and cryogenically freezing the fried portions.
    Type: Application
    Filed: December 13, 2013
    Publication date: May 28, 2015
    Inventors: Bianca van der Kolk, Wilhelmus Johannes Gerardus Michiels, Keith Graham Pickford
  • Publication number: 20150133425
    Abstract: The present invention relates to substituted thienopyrimidine compounds of general formula (I) as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: May 17, 2013
    Publication date: May 14, 2015
    Inventors: Georg Kettschau, Florian Puehler, Knut Eis, Ulrich Klar, Dirk Kosemund, Detlev Sülzle, Philip Lienau, Andrea Hägebarth, Ulf Bömer, Lars Wortmann, Keith Graham, Antje Margret Wengner
  • Publication number: 20150086697
    Abstract: A method of manufacture of a breadcrumb coating for a food product provides a crumb with an extremely low moisture content without the need for substantial energy input. The method achieves such very low moisture content without significant adverse effect on product quality.
    Type: Application
    Filed: October 2, 2014
    Publication date: March 26, 2015
    Inventors: Keith Graham Pickford, Kees van Doorn, Carry Reichgelt
  • Patent number: 8968701
    Abstract: The invention relates to a process for the production of radiotracers. In particular, this invention relates the isolation of radiotracers with containers filled with a stationary phase.
    Type: Grant
    Filed: July 6, 2010
    Date of Patent: March 3, 2015
    Assignee: Piramal Imaging SA
    Inventors: Holger Siebeneicher, Keith Graham, Mathias Berndt
  • Publication number: 20150011773
    Abstract: This invention relates to novel compounds suitable for labeling by 18F and to the corresponding 18F labeled compounds themselves, 19F-fluorinated analogues thereof and their use as reference standards, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging by Positron Emission Tomography (PET).
    Type: Application
    Filed: April 30, 2012
    Publication date: January 8, 2015
    Applicant: PIRAMAL IMAGING SA
    Inventors: Mathias Berndt, Andre Muller, Heribert Schmitt-Willich, Timo Stellfeld, Georg Kettschau, Thomas Brumby, Keith Graham, Lutz Lehmann, Jorma Hassfeld, Martin Kruger