Patents by Inventor Keith Joseph CHAPPELL

Keith Joseph CHAPPELL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric molecules and uses thereof
    Patent number: 12116386
    Abstract: Disclosed are chimeric polypeptides based on viral membrane fusion proteins. More particularly, the present invention discloses chimeric polypeptides that comprise a virion surface exposed portion of a viral fusion protein and a heterologous structure-stabilizing moiety, and to complexes of those chimeric polypeptides. The present invention also discloses the use of these complexes in compositions and methods for eliciting an immune response to a fusion protein of an enveloped virus, or complex of the fusion protein, and/or for treating or preventing an enveloped virus infection. The present invention further discloses the use of the heterologous structure-stabilizing moiety for oligomerizing heterologous molecules of interest.
    Type: Grant
    Filed: January 11, 2022
    Date of Patent: October 15, 2024
    Assignee: The University of Queensland
    Inventors: Keith Joseph Chappell, Daniel Watterson, Paul Robert Young
  • CHIMERIC MOLECULES AND USES THEREOF
    Publication number: 20220127309
    Abstract: Disclosed are chimeric polypeptides based on viral membrane fusion proteins. More particularly, the present invention discloses chimeric polypeptides that comprise a virion surface exposed portion of a viral fusion protein and a heterologous structure-stabilizing moiety, and to complexes of those chimeric polypeptides. The present invention also discloses the use of these complexes in compositions and methods for eliciting an immune response to a fusion protein of an enveloped virus, or complex of the fusion protein, and/or for treating or preventing an enveloped virus infection. The present invention further discloses the use of the heterologous structure-stabilizing moiety for oligomerizing heterologous molecules of interest.
    Type: Application
    Filed: January 11, 2022
    Publication date: April 28, 2022
    Applicant: The University of Queensland
    Inventors: Keith Joseph CHAPPELL, Daniel WATTERSON, Paul Robert YOUNG
  • Chimeric molecules and uses thereof
    Patent number: 11254712
    Abstract: Disclosed are chimeric polypeptides based on viral membrane fusion proteins. More particularly, the present invention discloses chimeric polypeptides that comprise a virion surface exposed portion of a viral fusion protein and a heterologous structure-stabilizing moiety, and to complexes of those chimeric polypeptides. The present invention also discloses the use of these complexes in compositions and methods for eliciting an immune response to a fusion protein of an enveloped virus, or complex of the fusion protein, and/or for treating or preventing an enveloped virus infection. The present invention further discloses the use of the heterologous structure-stabilizing moiety for oligomerizing heterologous molecules of interest.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: February 22, 2022
    Assignee: The University of Queensland
    Inventors: Keith Joseph Chappell, Daniel Watterson, Paul Robert Young
  • CHIMERIC MOLECULES AND USES THEREOF
    Publication number: 20200040042
    Abstract: Disclosed are chimeric polypeptides based on viral membrane fusion proteins. More particularly, the present invention discloses chimeric polypeptides that comprise a virion surface exposed portion of a viral fusion protein and a heterologous structure-stabilizing moiety, and to complexes of those chimeric polypeptides. The present invention also discloses the use of these complexes in compositions and methods for eliciting an immune response to a fusion protein of an enveloped virus, or complex of the fusion protein, and/or for treating or preventing an enveloped virus infection. The present invention further discloses the use of the heterologous structure-stabilizing moiety for oligomerizing heterologous molecules of interest.
    Type: Application
    Filed: March 29, 2018
    Publication date: February 6, 2020
    Inventors: Keith Joseph CHAPPELL, Daniel WATTERSON, Paul Robert YOUNG