Abstract: A management system includes a plurality of resources configured to be electrically connected to an external power supply, and a management device configured to manage the resources. The management device includes a planning unit and a management unit. The planning unit is configured to determine a power balancing plan of each of the resources by using first information on a use schedule of each of the resources and second information indicating a magnitude of an environmental load in a process of generating electric power to be supplied by the external power supply. The management unit is configured to manage the resources to cause each of the resources to operate according to the power balancing plan or a modified power balancing plan in power balancing of the external power supply.

Abstract: Provided are a cell image evaluation device, method, and program which are capable of more accurate and high reliable evaluation even though a captured image of each part to be observed within a container deteriorates. The cell image evaluation device includes an image evaluation unit that evaluates a state of a cell included in a captured image obtained by capturing an inside of the container that contains the cell based on the captured image, and a deterioration determination unit that determines whether or not the captured image deteriorates. The image evaluation unit changes an evaluation method of the captured image according to a determination result of the deterioration determination unit.

Abstract: An image generation device includes: a detection unit 43 that performs processing of detecting a specific feature from a plurality of focus images which include an observation target and are in different focus states; a determination unit 44 that determines a parameter indicating a degree of application of a region image to a combination region image in a case where the combination region image is generated from the region image, for each set of the region images in a plurality of corresponding regions respectively corresponding to the plurality of focus images, based on the specific feature detected by the detection unit 43; and a generation unit 45 that generates the combination region image by combining the region images for each of the plurality of corresponding regions based on the parameter determined by the determination unit 44.

Abstract: An information processing apparatus that executes processing of obtaining, from an interference fringe image that is a two-dimensional distribution of intensity of interference fringes of object light and reference light, a phase difference image that is a two-dimensional distribution of a phase difference between the object light and the reference light, and obtaining a shape of an object to be observed based on the phase difference image includes at least one processor configured to acquire object-related information regarding the object to be observed, read out, from a storage unit in which the object-related information and a shape profile indicating the shape of the object to be observed are stored in association with each other, the shape profile corresponding to the acquired object-related information, and perform phase connection with respect to the phase difference image with reference to the read-out shape profile.

Abstract: By moving at least one of a culture container having a plurality of wells or an imaging optical system that forms an image of an observation target in each of the wells, an observation position in the culture container is scanned to observe the observation target. In a case where an auto-focus control for each observation position is performed, a start timing of the auto-focus control for each observation position is switched on the basis of a boundary portion between the adjacent wells in a scanning direction of the observation position.

Abstract: An observation apparatus, an observation method, and an observation program capable of capturing an image by appropriately adjusting a focus regardless of a size of an effective range in which a distance to a cultivation container can be measured within a field of view are provided.

Abstract: There are provided a microscope apparatus, an observation method, and a microscope apparatus-control program that can more efficiently perform auto-focus control and can shorten an imaging time in a case where a culture vessel is to be scanned by an image forming optical system and the auto-focus control is to be performed at each observation position. Focus information of a culture vessel is detected by a first displacement sensor and a second displacement sensor while a stage is moved to a scanning measurement position from an initial set position, and an auto-focus control unit performs auto-focus control at every observation position on the basis of the focus information in a case where the stage has been moved to the scanning measurement position.

Abstract: An observation device includes: a stage on which a vessel in which a subject is stored is installed; an image-forming optical system that includes an objective lens forming an image of the subject stored in the vessel; a scan control unit that moves the stage with respect to the image-forming optical system to scan each observation position in the vessel by the image-forming optical system; and an acceleration-determination-information acquisition unit that acquires at least one piece of information among information about the subject, information about the vessel, information about an observation method, or information about an observation condition. The scan control unit controls an acceleration of the stage on the basis of the at least one piece of information.

Abstract: Provided are a captured image evaluation apparatus, a captured image evaluation method, and a captured image evaluation program capable of evaluating a thickness and a density of stacked cultured cells in a short imaging time. The captured image evaluation apparatus includes: an image acquisition section 52 that acquires captured images obtained by imaging a subject under a condition in which a numerical aperture of an objective lens is changed; a thickness estimation section 53 that estimates a thickness of the subject on the basis of a low NA captured image obtained under a condition in which the numerical aperture of the objective lens is relatively small; and a density estimation section 54 that estimates a density of the subject on the basis of a high NA captured image obtained under a condition in which the numerical aperture of the objective lens is relatively large.

Abstract: A cell observation apparatus includes an image formation optical system control unit 51 which sets an initial scanning range of the focal position based on information relating to a thickness of a cell, forms an image of the cell at each of a plurality of focal positions within a set initial scanning range, subsequently acquires an image captured by an imaging unit 40 for each of the plurality of focal positions, estimates the thickness of the cell based on the image, updates the initial scanning range of the focal position based on the estimated thickness of the cell, and forms an image of the cell at each of a plurality of focal positions within the updated scanning range.

Abstract: A microscope includes an illumination light emission unit 10 that emits illumination light, a stage 61 on which a culture container 60 is placed, an objective lens 31 on which the illumination light having passed through the culture container 60 and the stage 61 is incident, a focusing light emission unit 70 that emits focusing light, a reflected light detection unit 75 that detects reflected light due to emission of the focusing light, a distance changing unit 34 that changes a distance between the objective lens 31 and the stage 61, an autofocus control unit 51 that performs autofocus control based on the reflected light, and a focus control information acquisition unit 53 that acquires focus control information including information of the culture container 60, the amount of culture solution C, and the magnification of the objective lens 31.

Abstract: Provided is an information processing apparatus including an acquiring unit that acquires cell information indicating a state of a cell from production of a pluripotent stem cell to differentiation of the pluripotent stem cell into a specific differentiated cell by differentiation induction, and process history information indicating a history of a processing process for obtaining the differentiated cell, and a deriving unit that derives differentiation potency information indicating differentiation potency of the pluripotent stem cell based on the cell information and the process history information which are acquired by the acquiring unit.

Abstract: An image generation device includes: a detection unit 43 that performs processing of detecting a specific feature from a plurality of focus images which include an observation target and are in different focus states; a determination unit 44 that determines a parameter indicating a degree of application of a region image to a combination region image in a case where the combination region image is generated from the region image, for each set of the region images in a plurality of corresponding regions respectively corresponding to the plurality of focus images, based on the specific feature detected by the detection unit 43; and a generation unit 45 that generates the combination region image by combining the region images for each of the plurality of corresponding regions based on the parameter determined by the determination unit 44.

Abstract: An observation device includes: a structured illumination section; a phase difference measurement illumination section; a phase contrast lens that has a phase plate for dimming illumination light for phase difference measurement, where the illumination light for phase difference measurement is incident into the lens, and the structured illumination light is incident into the lens from a side opposite to an incidence side of the ring-shaped illumination; a detection section that detects reflected light of the structured illumination light; and an observation section that images the illumination light for phase difference measurement. When Fourier transform is performed on the structured illumination light, a spatial frequency of the structured illumination light is set on a high-frequency side or a low-frequency side with respect to a position of the phase plate on optical Fourier space.

Abstract: The phase contrast microscope includes: an illumination optical system 10 that emits illumination light for phase difference measurement to an observation target placed in a container; an adjustment optical system 20 that is provided between the illumination optical system 10 and the observation target S, has at least one optical element 21, and adjusts refraction of the illumination light due to a liquid surface shape of a liquid C in the container 60; an imaging unit 40 that images the observation target to which the illumination light has been emitted; and an adjustment optical system control unit 51 that adjusts optical characteristics of the adjustment optical system 20 based on uniformity of a density of an image captured by the imaging unit 40 and a density contrast.

Abstract: The observation apparatus includes an imaging unit that images an observation target accommodated in a cultivation container, a movement unit that scans the observation target by relatively moving the cultivation container with respect to the imaging unit in accordance with a scheduled trajectory, a measurement unit that acquires measured shape information of the cultivation container by measuring the cultivation container along a scanning trajectory using an observation region, a storage unit that stores reference shape information obtained by measuring a shape of the cultivation container using the measurement unit along a reference trajectory which is a reference in a case where the shape of the cultivation container is measured, a calculation unit that calculates a shift of a scanning trajectory with respect to a reference trajectory based on the reference shape information and the measured shape information, and a control unit that corrects the scheduled trajectory based on the shift and scans the imagin

Abstract: By moving at least one of a culture container having a plurality of wells or an imaging optical system that forms an image of an observation target in each of the wells, an observation position in the culture container is scanned to observe the observation target. In a case where an auto-focus control for each observation position is performed, a start timing of the auto-focus control for each observation position is switched on the basis of a boundary portion between the adjacent wells in a scanning direction of the observation position.

Abstract: An observation apparatus, an observation method, and an observation program capable of capturing an image by appropriately adjusting a focus regardless of a size of an effective range in which a distance to a cultivation container can be measured within a field of view are provided.

Abstract: An observation apparatus includes an imaging unit that images a container accommodating an observation target in an accommodation part and the observation target in a field of view smaller than the accommodation part at predetermined imaging positions and acquires a series of partial images, a movement unit that relatively moves at least one of the container or the imaging unit with respect to the other, a calculation unit that calculates partial shape information representing a partial shape of the container from the partial image obtained by imaging performed by the imaging unit, a storage unit that stores reference shape information representing a shape of the container, and a control unit that corrects the imaging position in a case where the partial image scheduled to be subsequently captured during acquisition of the series of partial images is captured based on the partial shape information and the reference shape information, and causes the imaging unit to perform imaging based on the corrected imagin

Abstract: A culture vessel that houses a culture liquid and a specimen is irradiated with pattern light having a pattern that is previously set for the culture vessel. Transmitted light transmitted through the culture liquid in the culture vessel because of the irradiation with the pattern light is detected. Optical characteristics of an adjusting optical system that adjusts refraction of light caused by the shape of the liquid surface of the culture liquid in the culture vessel are adjusted, on the basis of a detection signal based on the detected transmitted light. After the adjustment, the culture vessel is irradiated with illumination light for phase-contrast measurement, and the specimen irradiated with the illumination light is imaged.