Patents by Inventor Kentaro Nagane

Kentaro Nagane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for suppressing bitterness of quinoline derivative
    Patent number: 11090386
    Abstract: The present invention provides a method for suppressing bitterness of a quinoline derivative.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: August 17, 2021
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Kentaro Nagane, Yosuke Ueki, Shusuke Sano, Takahisa Sakaguchi
  • Method for Suppressing Bitterness of Quinoline Derivative
    Publication number: 20180318422
    Abstract: The present invention provides a method for suppressing bitterness of a quinoline derivative.
    Type: Application
    Filed: July 18, 2018
    Publication date: November 8, 2018
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Kentaro Nagane, Yosuke Ueki, Shusuke Sano, Takahisa Sakaguchi
  • Pharmaceutical composition of fused aminodihydrothiazine derivative
    Patent number: 10117876
    Abstract: The present invention provides a pharmaceutical composition comprising a compound represented by formula (1): or N-[3-((4aS,5R,7aS)-2-amino-5-methyl-4a,5,7,7a-tetrahydro-4H-furo[3,4-d] [1,3]thiazin-7a-yl)-4-fluorophenyl]-5-difluoromethylpyrazine-2-carboxamide, or a pharmaceutically acceptable salt of the foregoing, and a salt of a compound having a C12-22 saturated aliphatic hydrocarbon group.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: November 6, 2018
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Yasuhiro Zaima, Kazuo Kazama, Shuntaro Arase, Kentaro Nagane, Kanta Horie, Yosuke Ueki
  • PHARMACEUTICAL COMPOSITION OF FUSED AMINODIHYDROTHIAZINE DERIVATIVE
    Publication number: 20180263998
    Abstract: The present invention provides a pharmaceutical composition comprising a compound represented by formula (1): or N-[3-((4aS,5R,7aS)-2-amino-5-methyl-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl]-5-difluoromethylpyrazine-2-carboxamide, or a pharmaceutically acceptable salt of the foregoing, and a salt of a compound having a C12-22 saturated aliphatic hydrocarbon group.
    Type: Application
    Filed: October 8, 2015
    Publication date: September 20, 2018
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Yasuhiro Zaima, Kazuo Kazama, Shuntaro Arase, Kentaro Nagane, Kanta Horie, Yosuke Ueki
  • Pharmaceutical composition of fused aminodihydrothiazine derivative
    Patent number: 10076524
    Abstract: The present invention provides a pharmaceutical composition comprising a compound represented by formula (1): or N-[3-((4aS,5R,7aS)-2-amino-5-methyl-4a,5,7,7a-tetrahydro-4H-furo[3,4-d] [1,3]thiazin-7a-yl)-4-fluorophenyl]-5-difluoromethylpyrazine-2-carboxamide, or a pharmaceutically acceptable salt of the foregoing, and a salt of a compound having a C12-22 saturated aliphatic hydrocarbon group.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: September 18, 2018
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Yasuhiro Zaima, Kazuo Kazama, Shuntaro Arase, Kentaro Nagane, Kanta Horie, Yosuke Ueki
  • Method for Suppressing Bitterness of Quinoline Derivative
    Publication number: 20180028662
    Abstract: The present invention provides a method for suppressing bitterness of a quinoline derivative.
    Type: Application
    Filed: February 23, 2016
    Publication date: February 1, 2018
    Inventors: Kentaro Nagane, Yosuke Ueki, Shusuke Sano, Takahisa Sakaguchi
  • COMPRESSED COMPOSITION
    Publication number: 20130189360
    Abstract: An object of the present invention is to provide a compressed composition that is superior in terms of maintaining the function of a film or in terms of content uniformity even during tableting process. The present invention provides a compressed composition, comprising: coated granules containing a physiologically active compound or pharmacologically acceptable salt thereof, and an excipient, wherein the excipient contains at least one selected from the group consisting of low-substituted hydroxypropylcellulose, lactose and crystalline cellulose, and the total amount thereof is 0.5 parts by weight or more in 1 part by weight of the excipient, and the excipient is physically mixed with or coated onto the coated granules followed by compressing at low pressure.
    Type: Application
    Filed: August 3, 2011
    Publication date: July 25, 2013
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Hirokazu Sakamoto, Kentaro Nagane, Masami Nohara