Patents by Inventor Keonseung LIM

Keonseung LIM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted indazoles as hematopoietic progenitor kinase 1 (HPK1) inhibitors
    Patent number: 11834467
    Abstract: The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salts thereof, a composition comprising the compound, methods of using the compound for the treatment of various disorders associated with HPK1, and methods of preparing these compounds.
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: December 5, 2023
    Assignee: 1ST Biotherapeutics, Inc.
    Inventors: Jinhwa Lee, Suyeon Jo, Keonseung Lim, A Yeong Park, Gadhe Changdev Gorakshnath, Hwajung Nam, Yeonguk Jeon, Yejin Hwang, Jae Eun Kim, Misoon Kim, Seung Mook Lim
  • IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISORDERS
    Publication number: 20230365557
    Abstract: The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salt, stereoisomers thereof, a pharmaceutical composition comprising the compound, and a method to treat or prevent neurodegenerative diseases using the compound.
    Type: Application
    Filed: July 19, 2023
    Publication date: November 16, 2023
    Inventors: Jinhwa LEE, Suyeon JO, Keonseung LIM, A Yeong PARK, Jae Eun KIM, Misoon KIM, Seung Mook LIM
  • Imidazopyridinyl compounds and use thereof for treatment of neurodegenerative disorders
    Patent number: 11802126
    Abstract: The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salt, stereoisomers thereof, a pharmaceutical composition comprising the compound, and a method to treat or prevent neurodegenerative diseases using the compound.
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: October 31, 2023
    Assignee: 1ST Biotherapeutics, Inc.
    Inventors: Jinhwa Lee, Suyeon Jo, Keonseung Lim, A Yeong Park, Jae Eun Kim, Misoon Kim, Seung Mook Lim
  • 2-amino-3-carbonyl imidazopyridine and pyrazolopyridine compounds
    Patent number: 11744824
    Abstract: The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salt, stereoisomers thereof, a pharmaceutical composition comprising the compound, and a method for treating or preventing an inflammatory and autoimmune diseases, especially neuroinflammation diseases using the compound.
    Type: Grant
    Filed: September 14, 2021
    Date of Patent: September 5, 2023
    Assignee: 1ST Biotherapeutics, Inc.
    Inventors: Jinhwa Lee, Suyeon Jo, Keonseung Lim, A Yeong Park, Gadhe Changdev Gorakshnath, Hwajung Nam, Yeonguk Jeon, Yejin Hwang, Jae Eun Kim, Misoon Kim, Inyoung Yang
  • Indazoles as hematopoietic progenitor kinase 1 (HPK1) inhibitors and methods using same
    Patent number: 11649255
    Abstract: The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salts thereof, a composition comprising the compound, methods of using the compound for the treatment of various disorders associated with HPK1, and methods of preparing these compounds.
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: May 16, 2023
    Assignee: 1ST Biotherapeutics, Inc.
    Inventors: Jinhwa Lee, Suyeon Jo, Keonseung Lim, A Yeong Park, Gadhe Changdev Gorakshnath, Hwajung Nam, Yeonguk Jeon, Yejin Hwang, Jae Eun Kim, Misoon Kim, Seung Mook Lim
  • IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF PROLIFERATIVE DISORDERS
    Publication number: 20220242861
    Abstract: The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salt, stereoisomers thereof, a pharmaceutical composition comprising the compound, and a method to treat or prevent cancer diseases and/or proliferative disorders using the compound.
    Type: Application
    Filed: February 21, 2020
    Publication date: August 4, 2022
    Inventors: Jinhwa LEE, Suyeon JO, Keonseung LIM, A Yeong PARK, Jae Eun KIM, Misoon KIM, Inyoung YANG
  • INDAZOLES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND METHODS USING SAME
    Publication number: 20220098219
    Abstract: The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salts thereof, a composition comprising the compound, methods of using the compound for the treatment of various disorders associated with HPK1, and methods of preparing these compounds.
    Type: Application
    Filed: September 27, 2021
    Publication date: March 31, 2022
    Inventors: Jinhwa LEE, Suyeon JO, Keonseung LIM, A Yeong PARK, Gadhe Changdev GORAKSHNATH, Hwajung NAM, Yeonguk JEON, Yejin HWANG, Jae Eun KIM, Misoon KIM, Seung Mook LIM
  • INDAZOLES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND METHODS USING SAME
    Publication number: 20220098193
    Abstract: The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salts thereof, a composition comprising the compound, methods of using the compound for the treatment of various disorders associated with HPK1, and methods of preparing these compounds.
    Type: Application
    Filed: September 27, 2021
    Publication date: March 31, 2022
    Inventors: Jinhwa LEE, Suyeon JO, Keonseung LIM, A Yeong PARK, Gadhe Changdev GORAKSHNATH, Hwajung NAM, Yeonguk JEON, Yejin HWANG, Jae Eun KIM, Misoon KIM, Seung Mook LIM
  • 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS
    Publication number: 20220087985
    Abstract: The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salt, stereoisomers thereof, a pharmaceutical composition comprising the compound, and a method for treating or preventing an inflammatory and autoimmune diseases, especially neuroinflammation diseases using the compound.
    Type: Application
    Filed: September 14, 2021
    Publication date: March 24, 2022
    Inventors: Jinhwa LEE, Suyeon JO, Keonseung LIM, A Yeong PARK, Gadhe Changdev GORAKSHNATH, Hwajung NAM, Yeonguk JEON, Yejin HWANG, Jae Eun KIM, Misoon KIM, Inyoung YANG
  • IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISORDERS
    Publication number: 20210347774
    Abstract: The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salt, stereoisomers thereof, a pharmaceutical composition comprising the compound, and a method to treat or prevent neurodegenerative diseases using the compound.
    Type: Application
    Filed: July 12, 2021
    Publication date: November 11, 2021
    Inventors: Jinhwa LEE, Suyeon JO, Keonseung LIM, A Yeong PARK, Jae Eun KIM, Misoon KIM, Seung Mook LIM
  • Imidazopyridinyl compounds and use thereof for treatment of neurodegenerative disorders
    Patent number: 11098044
    Abstract: The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salt, stereoisomers thereof, a pharmaceutical composition comprising the compound, and a method to treat or prevent neurodegenerative diseases using the compound.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: August 24, 2021
    Assignee: 1ST Biotherapeutics, Inc.
    Inventors: Jinhwa Lee, Suyeon Jo, Keonseung Lim, A Yeong Park, Jae Eun Kim, Misoon Kim, Seung Mook Lim
  • Benzothiazol compounds and methods using the same for treating neurodegenerative disorders
    Patent number: 10968188
    Abstract: The present disclosure provides a compound of general Formula (I) having c-abl kinase inhibitory activity or pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the compound, and a method useful to treat or prevent neurodegenerative diseases using the compound.
    Type: Grant
    Filed: May 14, 2020
    Date of Patent: April 6, 2021
    Assignee: 1st Biotherapeutics, Inc.
    Inventors: Jinhwa Lee, Suyeon Jo, A Yeong Park, Gwibin Lee, Jae Eun Kim, Misoon Kim, Gyooseung Jung, Seung Mook Lim, Keonseung Lim, Minwoo Lee, Heekyoung Yang, Hyonam Kim, Hyeongjun Kim, Wanjun Li, Mingzhu Fan
  • BENZOTHIAZOL COMPOUNDS AND METHODS USING THE SAME FOR TREATING NEURODEGENERATIVE DISORDERS
    Publication number: 20200270222
    Abstract: The present disclosure provides a compound of general Formula (I) having c-abl kinase inhibitory activity or pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the compound, and a method useful to treat or prevent neurodegenerative diseases using the compound.
    Type: Application
    Filed: May 14, 2020
    Publication date: August 27, 2020
    Inventors: Jinhwa LEE, Suyeon JO, A Yeong PARK, Gwibin LEE, Jae Eun KIM, Misoon KIM, Gyooseung JUNG, Seung Mook LIM, Keonseung LIM, Minwoo LEE, Heekyoung YANG, Hyonam KIM, Hyeongjun KIM, Wanjun LI, Mingzhu FAN
  • IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISORDERS
    Publication number: 20200270246
    Abstract: The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salt, stereoisomers thereof, a pharmaceutical composition comprising the compound, and a method to treat or prevent neurodegenerative diseases using the compound.
    Type: Application
    Filed: February 21, 2020
    Publication date: August 27, 2020
    Inventors: Jinhwa LEE, Suyeon JO, Keonseung LIM, A Yeong PARK, Jae Eun KIM, Misoon KIM, Seung Mook LIM
  • Benzothiazol compounds and methods using the same for treating neurodegenerative disorders
    Patent number: 10669246
    Abstract: The present disclosure provides a compound of general Formula (I) having c-abl kinase inhibitory activity or pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the compound, and a method useful to treat or prevent neurodegenerative diseases using the compound.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: June 2, 2020
    Assignee: 1ST Biotherapeutics, Inc.
    Inventors: Jinhwa Lee, Suyeon Jo, Gwibin Lee, Keonseung Lim, A Yeong Park, Wanjun Li, Mingzhu Fan
  • BENZOTHIAZOL COMPOUNDS AND METHODS USING THE SAME FOR TREATING NEURODEGENERATIVE DISORDERS
    Publication number: 20190100500
    Abstract: The present disclosure provides a compound of general Formula (I) having c-abl kinase inhibitory activity or pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the compound, and a method useful to treat or prevent neurodegenerative diseases using the compound.
    Type: Application
    Filed: October 1, 2018
    Publication date: April 4, 2019
    Inventors: Jinhwa LEE, Jae Eun KIM, Suyeon JO, Gwibin LEE, Keonseung LIM, A Yeong PARK, Misoon KIM, Gyooseung JUNG, Seung Mook LIM, Minwoo LEE, Heekyoung YANG, Hyonam KIM, Hyeongjun KIM, Wanjun LI, Mingzhu FAN