Abstract: The invention relates to an ultrafiltration unit for continuous buffer or medium exchange, a method for continuous buffer or medium exchange in the ultrafiltration unit, and a plant in particular for (semi)continuous production of biopharmaceutical and biological macromolecular products in particular, such as proteins, e.g. monoclonal antibodies and vaccines, comprising the ultrafiltration unit according to the invention.

Abstract: The invention provides a method for the continuous elution of a biopharmaceutical, biological, macromolecular product from more than one chromatography column, comprising the steps of: (a) providing a product stream via an inlet, (b) simultaneously loading n front chromatography columns with the product stream in a loading zone with a loading time tB, an outlet stream of the n front chromatography columns being simultaneously distributed to at least n-1 recovery chromatography columns in a recovery zone, where n is between 1 and 5, and where the n front chromatography columns at a given time point have a varying loading time tB between 0 and L1, between L1 and L2, and up to between Ln-1 and Ln, where each front chromatography column has a total loading time of Ln, characterized in that, periodically after a constant switch time tS of Ln-1, the front chromatography column n comes out of the loading zone and a recovery chromatography column from the recovery zone enters the loading zone, (c) washing the product

Abstract: The invention relates to an ultrafiltration unit for continuous buffer or medium exchange, a method for continuous buffer or medium exchange in the ultrafiltration unit, and a plant in particular for (semi)continuous production of biopharmaceutical and biological macromolecular products in particular, such as proteins, e.g. monoclonal antibodies and vaccines, comprising the ultrafiltration unit according to the invention.

Abstract: Method and appliance for carrying out membrane electrophoresis using microfiltration or ultrafiltration membranes, wherein the electroosmotic flow which develops in the membrane pores is reduced or offset by pressure superposition.

Abstract: Method and appliance for carrying out membrane electrophoresis using microfiltration or ultrafiltration membranes, wherein the electroosmotic flow which develops in the membrane pores is reduced or offset by pressure superposition.

Abstract: Process for the separation of substances present in dissolved and/or colloidal form, in particular of catalysts, from solutions in a nonaqueous solvent, with the aid of a membrane, wherein the solution is passed through a membrane which has a hydrophobic coating and a mean pore size of not more than 30 nm.