Patents by Inventor Kerstin HAGE
Kerstin HAGE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12258554Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.Type: GrantFiled: July 19, 2021Date of Patent: March 25, 2025Assignee: BASF SEInventors: Isabella Siepe, Heilke Brueser, Kristin Klappach, Karl-Heinrich Schneider, Petra Sproete, Kerstin Hage, Birgit Blanz, Eckhard Thines, Luis Antelo, Louis Pergaud Sandjo, Till Opatz
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Publication number: 20240093211Abstract: The present invention generally relates to the field of fermentation technology and microorganisms useful for such fermentations. The invention also relates to materials including nucleic acids and proteins useful for altering fermentation characteristics of microorganisms, and to microorganisms comprising such nucleic acids and/or proteins.Type: ApplicationFiled: September 8, 2023Publication date: March 21, 2024Inventors: Max Fabian Felle, Stefan Jenewein, Kerstin Hage, Holger Hartmann
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Patent number: 11788094Abstract: The present invention generally relates to the field of fermentation technology and microorganisms useful for such fermentations. The invention also relates to materials including nucleic acids and proteins useful for altering fermentation characteristics of microorganisms, and to microorganisms comprising such nucleic acids and/or proteins.Type: GrantFiled: December 8, 2016Date of Patent: October 17, 2023Assignee: BASF SEInventors: Max Fabian Felle, Stefan Jenewein, Kerstin Hage, Holger Hartmann
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Publication number: 20220340865Abstract: The present invention is directed to a method of preparing a fermentation medium comprising the steps of a) mixing components of a fermentation medium comprising a complex nutrient source in water, wherein the complex nutrient source is in an amount of 0.5-30% w/v of the fermentation medium; b) adjusting the pH of the fermentation medium obtained in step a) to a pH between pH 3.0 and pH 6.7; c) subjecting the fermentation medium subsequently to a heat treatment and thereafter adjusting the pH to a pH value suitable for cell cultivation. The present invention is further directed to a method a fermentation process comprising cultivation of the cells in the fermentation medium of the invention and the production of a compound of interest. The present invention is further directed to a method for reducing color formation and viscosity during fermentation medium preparation and during the fermentation process.Type: ApplicationFiled: June 29, 2020Publication date: October 27, 2022Inventors: Thomas Kaeding, Kerstin Hage, Rodolfo Ham-Zhu
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Publication number: 20210355433Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.Type: ApplicationFiled: July 19, 2021Publication date: November 18, 2021Inventors: Isabella Siepe, Heilke Brueser, Kristin Klappach, Karl-Heinrich Schneider, Petra Sproete, Kerstin Hage, Birgit Blanz, Eckhard Thines, Luis Antelo, Louis Pergaud Sandjo, Till Opatz
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Patent number: 11064703Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.Type: GrantFiled: October 4, 2017Date of Patent: July 20, 2021Assignee: BASF SEInventors: Isabella Siepe, Heike Brueser, Kristin Klappach, Karl-Heinrich Schneider, Petra Sproete, Kerstin Hage, Birgit Blanz, Eckhard Thines, Luis Antelo, Louis Pergaud Sandjo, Till Opatz
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Patent number: 10548326Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.Type: GrantFiled: October 4, 2017Date of Patent: February 4, 2020Assignee: BASF SEInventors: Isabella Siepe, Heike Brueser, Kristin Klappach, Karl-Heinrich Schneider, Petra Sproete, Kerstin Hage, Birgit Blanz, Eckhard Thines, Luis Antelo, Louis Pergaud Sandjo, Till Opatz
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Publication number: 20190292514Abstract: The present invention is directed to a fermentation medium and a fermentation method using said fermentation medium wherein the fermentation medium comprising a basal medium and a chelating agent having the formula (I) R1—CH(COOX1)—N(CH2COOX1)2, wherein R1 is selected from hydrogen, linear or branched C1-C4-alkyl, phenyl, benzyl, CH2OH, and CH2CH2COOX1, X1 is (MxH1-x), M being a monovalent cation, preferably being selected from ammonium or alkali metal or combinations of at least two of the foregoing, x is in the range of from zero to 1, wherein x is an average value.Type: ApplicationFiled: July 12, 2017Publication date: September 26, 2019Inventors: Kerstin Hage, Carsten Schwalb, Gunter Steigelmann, Thomas Kaeding, Sebastian Briechle
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Publication number: 20190112612Abstract: The present invention generally relates to the field of fermentation technology and microorganisms useful for such fermentations. The invention also relates to materials including nucleic acids and proteins useful for altering fermentation characteristics of microorganisms, and to microorganisms comprising such nucleic acids and/or proteins.Type: ApplicationFiled: December 8, 2016Publication date: April 18, 2019Inventors: Max Fabian Felle, Stefan Jenewein, Kerstin Hage, Holger Hartmann
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Publication number: 20180020674Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.Type: ApplicationFiled: October 4, 2017Publication date: January 25, 2018Inventors: Isabella SIEPE, Heike BRUESER, Kristin KLAPPACH, Karl-Heinrich SCHNEIDER, Petra SPROETE, Kerstin HAGE, Birgit BLANZ, Eckhard THINES, Luis ANTELO, Louis Pergaud SANDJO, Till OPATZ
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Publication number: 20180020675Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.Type: ApplicationFiled: October 4, 2017Publication date: January 25, 2018Inventors: Isabella SIEPE, Heike BRUESER, Kristin KLAPPACH, Karl-Heinrich SCHNEIDER, Petra SPROETE, Kerstin HAGE, Birgit BLANZ, Eckhard THINES, Luis ANTELO, Louis Pergaud SANDJO, Till OPATZ
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Publication number: 20170260519Abstract: The present invention relates to methods for cultivating a nitrile hydratase producing microorganism, compositions for cultivating a nitrile hydratase producing microorganism, and use of compositions comprising a saccharide and an organic acid for cultivating a nitrile hydratase producing microorganism. The composition provided in and to be employed in context with the present invention is particularly suitable for inducing both, growth and nitrile hydratase production of corresponding microorganisms.Type: ApplicationFiled: September 30, 2015Publication date: September 14, 2017Applicant: BASF SEInventors: Kerstin HAGE, Carsten SCHWALB, Petra SPROETE, Peter OEDMAN, Kai-Uwe BALDENIUS, Burkhard ERNST, Gunter STEIGELMANN, Stephan FREYER, Claus BOLLSCHWEILER, Michael Guenter BRAUN, Juergen DAEUWEL
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Publication number: 20170223968Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.Type: ApplicationFiled: August 4, 2015Publication date: August 10, 2017Inventors: Isabella SIEPE, Heike BRUSER, Kristin KLAPPACH, Karl-Heinrich SCHNEIDER, Petra SPROTE, Kerstin HAGE, Birgit BLANZ, Eckhard THINES, Luis ANTELO, Louis Pergaud SANDJO, Till OPATZ