Abstract: A cardiovascular conditioning and therapeutic system which utilizes a mechanized powered exercise device for presenting a variable exercise work load to a user which in turn causes a corresponding variation in heart rate of the user. A heart rate transducer is operatively connected to the user, and an exercise work load transducer is operatively connected to the exercise device. A target heart rate for cardiovascular conditioning and therapy is determined, as is a conditioning period. The exercise device is actuated and incrementally increases work load until the user's heart rate comes within a predetermined margin of the heart rate. A control circuitry continuously monitors current heart rate and compares it with the target heart rate. Once current heart rate enters the predetermined margin around the target heart rate, the conditioning period begins.