Patents by Inventor Kimiko Ikeda

Kimiko Ikeda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200038332
    Abstract: The present application provides an orally-disintegrating tablet having excellent tablet hardness and disintegrability. The present application further provides a method of producing a disintegrative particulate composition including three components consisting of a first disintegrator component of an acid-type carboxymethylcellulose, a second disintegrator component and an excipient. The method includes a first wet granulation step using any two of the three components, and a second wet granulation step using granules obtained in the first wet granulation step and the remaining one component of the three components not used in the first wet granulation step. The production method may further includes a crystalline cellulose as a fourth component or a third step of mixing a crystalline cellulose into granules obtained in the second wet granulation step. Disintegrative particulate compositions obtained by these methods are also disclosed.
    Type: Application
    Filed: October 11, 2019
    Publication date: February 6, 2020
    Inventors: Takahiro HIRAMURA, Kiyoshi lkura, Sae ltaya, Tomohito Okabayashi, Naohiro Hashikawa, Tetsuro Morita, Kimiko Ikeda, Haruka Wakayama
  • Patent number: 10292934
    Abstract: An object of the present application is to provide an orally-disintegrating tablet having excellent tablet hardness and disintegrability, and including a disintegrative particulate composition. This invention relates to a disintegrative particulate composition comprising the four components consisting of a first disintegrator component of an acid-type carboxymethylcellulose, a second disintegrator component other than the acid-type carboxymethylcellulose, an excipient of a sugar or sugar alcohol, and crystalline cellulose; and to an orally-disintegrating tablet, including the disintegrative particulate composition and a medicinal ingredient.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: May 21, 2019
    Assignees: DAICEL CORPORATION, NICHIRIN CHEMICAL INDUSTRIES, LTD.
    Inventors: Takahiro Hiramura, Kiyoshi Ikura, Sae Ishikawa, Tomohito Okabayashi, Naohiro Hashikawa, Tetsuro Morita, Kimiko Ikeda
  • Publication number: 20180235889
    Abstract: An object of the present invention is to provide an orally disintegrating tablet (super-rapid disintegrating tablet) that is heavy and relatively thin, and has an extremely high disintegrability (short disintegration time), and a high tablet hardness, and to provide a simple method for the production of said super-rapid disintegrating tablet without such a complicated process as freeze-drying. This invention relates to an orally disintegrating tablet having a specific surface area of from 1.50 to 4.00 mm2/mg and a weight of from 100 to 300 mg, particularly having a disintegration time in water of 7 seconds or less and an oral disintegration time of 6 seconds or less, a method for the production of said orally disintegrating tablet, and to a disintegrative particulate composition for use in said method.
    Type: Application
    Filed: August 16, 2016
    Publication date: August 23, 2018
    Inventors: Tomohito OKABAYASHI, Atsuhiro UETOMO, Naohiro HASHIKAWA, Takahiro HIRAMURA, Tetsuro MORITA, Kimiko IKEDA
  • Publication number: 20160213619
    Abstract: An object of the present invention is to provide an orally disintegrating tablet having both an excellent tablet hardness and disintegrability even when the content of a medicinal ingredient is high. This invention relates to an orally disintegrating tablet comprising a medicinal ingredient having distribution coefficient (log P) in a range of from ?6.0 to 10.0 and a disintegrative particulate composition produced by granulation consisting of at least two stages, especially to said orally disintegrating tablet having tablet hardness of from 30 to 100 N, and disintegration time in water of from 10 to 30 sec.
    Type: Application
    Filed: September 24, 2014
    Publication date: July 28, 2016
    Inventors: Takahiro HIRAMURA, Kiyoshi IKURA, Sae ITAYA, Tomohito OKABAYASHI, Anan SAKAGUCHI, Tetsuro MORITA, Kimiko IKEDA
  • Publication number: 20150238424
    Abstract: An object of the present application is to provide an orally-disintegrating tablet having excellent tablet hardness and disintegrability, and including a disintegrative particulate composition. This invention relates to a disintegrative particulate composition comprising the four components consisting of a first disintegrator component of an acid-type carboxymethylcellulose, a second disintegrator component other than the acid-type carboxymethylcellulose, an excipient of a sugar or sugar alcohol, and crystalline cellulose; and to an orally-disintegrating tablet, including the disintegrative particulate composition and a medicinal ingredient.
    Type: Application
    Filed: September 13, 2013
    Publication date: August 27, 2015
    Inventors: Takahiro Hiramura, Kiyoshi Ikura, Sae Ishikawa, Tomohito Okabayashi, Naohiro Hashikawa, Tetsuro Morita, Kimiko Ikeda
  • Publication number: 20150174075
    Abstract: An object of the present application is to provide an orally-disintegrating tablet having excellent tablet hardness and disintegrability and a disintegrative particulate composition by which the orally-disintegrating tablet can be obtained with a relatively low tablet compression force and which can provide excellent moldability, as well as a method of producing the same, etc.
    Type: Application
    Filed: March 27, 2013
    Publication date: June 25, 2015
    Inventors: Takahiro Hiramura, Kiyoshi Ikura, Sae Itaya, Tomohito Okabayashi, Naohiro Hashikawa, Tetsuro Morita, Kimiko Ikeda, Haruka Wakayma
  • Patent number: D283255
    Type: Grant
    Filed: August 5, 1983
    Date of Patent: April 1, 1986
    Inventor: Kimiko Ikeda
  • Patent number: D283256
    Type: Grant
    Filed: August 5, 1983
    Date of Patent: April 1, 1986
    Inventor: Kimiko Ikeda
  • Patent number: D283257
    Type: Grant
    Filed: August 5, 1983
    Date of Patent: April 1, 1986
    Inventor: Kimiko Ikeda