Patents by Inventor Kiyoshi Nakayama

Kiyoshi Nakayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190192520
    Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.
    Type: Application
    Filed: March 4, 2019
    Publication date: June 27, 2019
    Inventors: Jean-Marc LAPIERRE, Sudharshan EATHIRAJ, Nivedita NAMDEV, Brian SCHWARTZ, Yusuke OTA, Takayuki MOMOSE, Tomoyuki TSUNEMI, Hiroaki INAGAKI, Kiyoshi NAKAYAMA
  • Publication number: 20190170376
    Abstract: [Problem to be Solved] To provide a gas humidity regulating method and a regulator that can regulate a temperature during humidity control and improve humidity-control efficiency. In an air humidity regulating method for gas subjected to treatment, a first medium 22 is caused to flow onto a heat exchanging pipe 17 of a gas-liquid contact part 18 in a dehumidifier 11; meanwhile, a second medium 24 is passed through the heat exchanging pipe 17. In this state, air is fed into a gas-liquid contact case 13 from an inlet port 14 and gas-liquid contact is made by the first medium 22 on the gas-liquid contact part 18 so as to absorb water content from the air into the first medium 22. The first medium 22 contains an ionic liquid having high absorbency. The temperature of the first medium 22 is regulated by the second medium 24. After that, treated air is discharged from an outlet port 15 of the gas-liquid contact case 13.
    Type: Application
    Filed: October 4, 2017
    Publication date: June 6, 2019
    Inventors: Xinming WANG, Hiroshi NAKAYAMA, Kiyoshi SAITO, Seiichi YAMAGUCHI, Olivier ZEHNACKER, Yoichi MIYAOKA
  • Publication number: 20190148945
    Abstract: Systems and methods for controlling battery charge levels to maximize savings in a behind the meter energy management system include predicting a demand charge threshold with a power demand management controller based on historical load. A net energy demand is predicted for a current day with a short-term forecaster. A demand threshold maximizes financial savings using the net energy demand using a rolling time horizon optimizer by concurrently optimizing the demand charge savings and demand response rewards. A load reduction capability factor of batteries is determined with a real-time controller corresponding to an amount of energy to fulfill the demand response rewards. The net energy demand is compared with the demand threshold to determine a demand difference. Battery charge levels of the one or more batteries are controlled with the real time controller according to the demand difference and the load reduction capability factor.
    Type: Application
    Filed: November 9, 2018
    Publication date: May 16, 2019
    Inventors: Kiyoshi Nakayama, Ratnesh Sharma, Ali Hooshmand
  • Publication number: 20190147552
    Abstract: Systems and methods for controlling battery charge levels to maximize savings in a behind the meter energy management system include predicting a demand charge threshold with a power demand management controller based on historical load. A net energy demand is predicted for a current day with a short-term forecaster. A demand threshold maximizes financial savings using the net energy demand using a rolling time horizon optimizer by concurrently optimizing the demand charge savings and demand response rewards. A load reduction capability factor of batteries is determined with a real-time controller corresponding to an amount of energy to fulfill the demand response rewards. The net energy demand is compared with the demand threshold to determine a demand difference. Battery charge levels of the one or more batteries are controlled with the real time controller according to the demand difference and the load reduction capability factor.
    Type: Application
    Filed: November 9, 2018
    Publication date: May 16, 2019
    Inventors: Kiyoshi Nakayama, Ratnesh Sharma, Ali Hooshmand
  • Publication number: 20190113549
    Abstract: A computer-implemented method, system, and computer program product are provided for anomaly detection in a power system. The method includes receiving, by a processor-device, a plurality of measurements from a plurality of meters throughout the power system. The method also includes generating, by the processor-device, temporal causal networks based on pair-wise relationships between the plurality of measurements from the plurality of meters over time. The method additionally includes determining, by the processor-device, invariant relationships for the plurality of meters between the temporal causal networks. The method further includes predicting, by the processor-device, an anomaly from the invariant relationships for the plurality of meters with a residual anomaly threshold. The method also includes disabling one of the plurality of meters that originated the anomaly.
    Type: Application
    Filed: October 4, 2018
    Publication date: April 18, 2019
    Inventors: Kiyoshi Nakayama, Chenrui Jin, Ratnesh Sharma, Nikhil Muralidhar
  • Patent number: 10245263
    Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: April 2, 2019
    Assignee: ArQule, Inc.
    Inventors: Jean-Marc Lapierre, Sudharshan Eathiraj, Nivedita Namdev, Brian Schwartz, Yusuke Ota, Takayuki Momose, Tomoyuki Tsunemi, Hiroaki Inagaki, Kiyoshi Nakayama
  • Publication number: 20180330250
    Abstract: A computer-implemented method for detecting and predicting anomalies in an energy management system is presented. The method includes detecting, in real-time, a first set of outliers for a plurality of energy devices under operation, predicting a second set of outliers for running the plurality of energy devices, analyzing historical energy data of the plurality of energy devices to extract a third set of outliers, receiving feedback, in real-time, from a user regarding each of the first, second, and third sets of outliers, and training the energy management system with the real-time feedback received from the user to automatically optimize a threshold of error detection.
    Type: Application
    Filed: May 8, 2018
    Publication date: November 15, 2018
    Applicant: NEC Laboratories America, Inc.
    Inventors: Kiyoshi Nakayama, Ratnesh Sharma
  • Patent number: 10103550
    Abstract: A method of aggregated virtual power plant (VPP) control includes receiving control variable values. The control variables are received for control variables related to energy production and loads of devices electrically coupled to an electrical grid and communicatively coupled to the VPP controller server. The method includes inputting the control variable values into an objective algorithm. The method may include executing the objective algorithm. Executing the objective algorithm includes adjusting energy loads and energy production of prosumers, adjusting an energy amount supplied from a supply side for multiple time intervals, and adjusting curtailment of the energy loads in the prosumers based thereon. The method includes generating a VPP DR event schedule and communicating it to VPP client servers. The VPP DR event schedule includes control signals that are configured to affect an operating condition of the devices that are controlled by the VPP client servers.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: October 16, 2018
    Assignee: FUJITSU LIMITED
    Inventors: Kiyoshi Nakayama, Wei-Peng Chen
  • Publication number: 20180169742
    Abstract: A forged crankshaft manufacturing apparatus processes a forged blank with no flash. The forged blank includes at least one rough crank arm having an excess portion protruding from an outer periphery of a side portion thereof. The manufacturing apparatus includes a first die and a second die paired with each other, a retaining device, and a moving device. The first die and the second die bend or crash the excess portion. The retaining device retains at least one of the rough journals or at least one of the rough pins such that a rough pin decentering direction is perpendicular to a reducing direction in which the first die and the second die apply force for reduction. The moving device supports the retaining device such that the retaining device is movable in the reducing direction.
    Type: Application
    Filed: May 19, 2016
    Publication date: June 21, 2018
    Inventors: Tomohisa YAMASHITA, Kunihiro YABUNO, Ken YOSHINO, Sho TAKAMOTO, Hiroyuki KUROKAWA, Kenji TAMURA, Junichi OKUBO, Kiyoshi NAKAYAMA, Toru HORIUCHI
  • Publication number: 20180055846
    Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of BTK, a pharmaceutical composition comprising a compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.
    Type: Application
    Filed: August 23, 2017
    Publication date: March 1, 2018
    Inventors: Craig BATES, Sudharshan Eathiraj, Hiroaki Inagaki, Jean-Marc Lapierre, Takayuki Momose, Kiyoshi Nakayama, Takashi Odagiri, Masahiro Ota, Yusuke Ota, Yoshihiro Shibata, Manish Tandon, Tomoyuki Tsunemi
  • Patent number: 9841293
    Abstract: An in-vehicle information apparatus includes a main unit having a display device, and a navigation unit providing a navigation function to the main unit. The navigation unit includes a navigation processing unit a sub unit providing an addition function to the navigation unit, and a navigation unit screen generating unit which generates a navigation unit screen for displaying information concerning a function which the navigation unit provides. The main unit includes an operation unit which receives an input for selecting a function from a user, a main unit screen generating unit which generates a main unit screen for displaying information concerning a function which the main unit provides, and a video selector which selects one of the navigation unit screen and the main unit screen.
    Type: Grant
    Filed: January 26, 2011
    Date of Patent: December 12, 2017
    Assignee: CALRION CO., LTD.
    Inventors: Kiyoshi Nakayama, Masato Takahashi
  • Patent number: 9811069
    Abstract: A servomotor control apparatus according to the present invention is a control apparatus for controlling a machine having one or a plurality of movable portions each driven by a servomotor. In the servomotor control apparatus, while an electromagnetic brake is operated, an actual position obtained by a position detector is periodically monitored. The actual position is compared with the actual position at the time of actuating the electromagnetic brake. When the actual positions are different by a predetermined value or more, any of the issue of a motor torque to maintain the position, the actuation of a regenerative brake, or a control means for continuing a control to maintain the position without operating the electromagnetic brake, even if the servomotor stops for a certain period of time during playback operation, is performed.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: November 7, 2017
    Assignee: FANUC CORPORATION
    Inventor: Kiyoshi Nakayama
  • Publication number: 20170244252
    Abstract: A computer-implemented method is provided for managing a plurality of micro grids in an energy system. The method includes collecting and maintaining, in a central database, configuration information and state information for the plurality of micro grids, by a processor-based dynamic operation engine. The method further includes identifying failures in any of the plurality of micro grids and generating updated configuration information and updated state information relating to the failures, based on data analytics and diagnostic polling applied to the configuration information and the state information, by a processor-based micro grid diagnostic engine.
    Type: Application
    Filed: February 17, 2017
    Publication date: August 24, 2017
    Inventors: Kiyoshi Nakayama, Ratnesh Sharma
  • Publication number: 20170207633
    Abstract: A method of aggregated virtual power plant (VPP) control includes receiving control variable values. The control variables are received for control variables related to energy production and loads of devices electrically coupled to an electrical grid and communicatively coupled to the VPP controller server. The method includes inputting the control variable values into an objective algorithm. The method may include executing the objective algorithm. Executing the objective algorithm includes adjusting energy loads and energy production of prosumers, adjusting an energy amount supplied from a supply side for multiple time intervals, and adjusting curtailment of the energy loads in the prosumers based thereon. The method includes generating a VPP DR event schedule and communicating it to VPP client servers. The VPP DR event schedule includes control signals that are configured to affect an operating condition of the devices that are controlled by the VPP client servers.
    Type: Application
    Filed: January 19, 2016
    Publication date: July 20, 2017
    Applicant: FUJITSU LIMITED
    Inventors: Kiyoshi NAKAYAMA, Wei-Peng CHEN
  • Publication number: 20170182053
    Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.
    Type: Application
    Filed: March 3, 2017
    Publication date: June 29, 2017
    Inventors: Jean-Marc LAPIERRE, Sudharshan EATHIRAJ, Nivedita NAMDEV, Brian SCHWARTZ, Yusuke OTA, Takayuki MOMOSE, Tomoyuki TSUNEMI, Hiroaki INAGAKI, Kiyoshi NAKAYAMA
  • Patent number: 9630968
    Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.
    Type: Grant
    Filed: December 23, 2015
    Date of Patent: April 25, 2017
    Assignee: ArQule, Inc.
    Inventors: Jean-Marc Lapierre, Sudharshan Eathiraj, Nivedita Namdev, Brian Schwartz, Yusuke Ota, Takayuki Momose, Tomoyuki Tsunemi, Hiroaki Inagaki, Kiyoshi Nakayama
  • Publication number: 20170038748
    Abstract: A servomotor control apparatus according to the present invention is a control apparatus for controlling a machine having one or a plurality of movable portions each driven by a servomotor. In the servomotor control apparatus, while an electromagnetic brake is operated, an actual position obtained by a position detector is periodically monitored. The actual position is compared with the actual position at the time of actuating the electromagnetic brake. When the actual positions are different by a predetermined value or more, any of the issue of a motor torque to maintain the position, the actuation of a regenerative brake, or a control means for continuing a control to maintain the position without operating the electromagnetic brake, even if the servomotor stops for a certain period of time during playback operation, is performed.
    Type: Application
    Filed: August 2, 2016
    Publication date: February 9, 2017
    Applicant: FANUC CORPORATION
    Inventor: Kiyoshi Nakayama
  • Publication number: 20140142096
    Abstract: A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.
    Type: Application
    Filed: November 19, 2013
    Publication date: May 22, 2014
    Applicant: Daiichi Sankyo Company, Limited
    Inventors: Hisashi Takahashi, Satoshi Komoriya, Takahiro Kitamura, Takashi Odagiri, Hiroaki Inagaki, Toshifumi Tsuda, Kiyoshi Nakayama, Makoto Takemura, Kenichi Yoshida, Rie Miyauchi, Masatoshi Nagamochi
  • Patent number: 8618094
    Abstract: A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: December 31, 2013
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Hisashi Takahashi, Satoshi Komoriya, Takahiro Kitamura, Takashi Odagiri, Hiroaki Inagaki, Toshifumi Tsuda, Kiyoshi Nakayama, Makoto Takemura, Kenichi Yoshida, Rie Miyauchi, Masatoshi Nagamochi
  • Publication number: 20130029977
    Abstract: A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.
    Type: Application
    Filed: July 2, 2009
    Publication date: January 31, 2013
    Inventors: Hisashi Takahashi, Satoshi Komoriya, Takahiro Kitamura, Takashi Odagiri, Hiroaki Inagaki, Toshifumi Tsuda, Kiyoshi Nakayama, Makoto Takemura, Kenichi Yoshida, Rie Miyauchi, Masatoshi Nagamochi