Patents by Inventor Klaas DeCanniere

Klaas DeCanniere has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMARKER PANEL AND METHODS FOR DETECTING MICROSATELLITE INSTABILITY IN CANCERS
    Publication number: 20240043938
    Abstract: The present invention generally relates to the field of cancer, in particular to cancers having microsatellite instability (MSI) and/or mismatch repair (MMR-) deficiency. Examples of such cancers include many colorectal, gastric, and endometrial tumors. Accordingly, the present invention provides a novel diagnostic marker panel for analyzing MSI loci, together with methods and kits of using said panel in the detection of cancers having microsatellite instability (MSI) and/or mismatch repair (MMR-) deficiency.
    Type: Application
    Filed: June 9, 2023
    Publication date: February 8, 2024
    Inventors: Bram De Craene, Klaas Decanniere, Jan Van De Velde, Geert Maertens
  • Biomarker panel and methods for detecting microsatellite instability in cancers
    Patent number: 11713488
    Abstract: The present invention generally relates to the field of cancer, in particular to cancers having microsatellite instability (MSI) and/or mismatch repair (MMR-) deficiency. Examples of such cancers include many colorectal, gastric, and endometrial tumors. Accordingly, the present invention provides a novel diagnostic marker panel for analyzing MSI loci, together with methods and kits of using said panel in the detection of cancers having microsatellite instability (MSI) and/or mismatch repair (MMR-) deficiency.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: August 1, 2023
    Assignee: BIOCARTIS NV
    Inventors: Bram De Craene, Klaas Decanniere, Jan Van De Velde, Geert Maertens
  • METHODS FOR THE ANALYSIS OF DISSOCIATION MELT CURVE DATA
    Publication number: 20210005286
    Abstract: The present invention relates to the use of wavelet transform to analyze raw melting curve data of nucleic acids. The effect is decreased noise sensitive calculations and increased computational efficiency and speed. The invention is particularly suitable for classifying test samples involving the combined analysis of several, multiplexed targets within one experiment generating large raw datasets requiring discrimination of minute variations in the data.
    Type: Application
    Filed: January 22, 2019
    Publication date: January 7, 2021
    Inventors: Bram De Craene, Klaas Decanniere, Jan Van De Velde
  • BIOMARKER PANEL AND METHODS FOR DETECTING MICROSATELLITE INSTABILITY IN CANCERS
    Publication number: 20200399705
    Abstract: The present invention generally relates to the field of cancer, in particular to cancers having microsatellite instability (MSI) and/or mismatch repair (MMR-) deficiency. Examples of such cancers include many colorectal, gastric, and endometrial tumors. Accordingly, the present invention provides a novel diagnostic marker panel for analyzing MSI loci, together with methods and kits of using said panel in the detection of cancers having microsatellite instability (MSI) and/or mismatch repair (MMR-) deficiency.
    Type: Application
    Filed: January 22, 2019
    Publication date: December 24, 2020
    Inventors: Bram De Craene, Klaas Decanniere, Jan Van De Velde
  • Automatable method for nucleic acid isolation
    Patent number: 10829758
    Abstract: The present invention relates to a highly automatable method for isolation and/or purification of nucleic acids from a biological sample, which is particularly suitable for nucleic acids-shorter than 250 bp and can be performed without a proteolytic pre-digestion step in an automated system, preferably a cartridge-based system. In a further aspect, the present invention also provides automated nucleic acid detection methods based on said isolation and/or purification method, as well as buffers and kits to be used in performing said methods.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: November 10, 2020
    Assignee: BIOCARTIS, NV
    Inventors: Geert Meersseman, Klaas DeCanniere
  • AUTOMATABLE METHOD FOR NUCLEIC ACID ISOLATION
    Publication number: 20180291367
    Abstract: The present invention relates to a highly automatable method for isolation and/or purification of nucleic acids from a biological sample, which is particularly suitable for nucleic acids-shorter than 250 bp and can be performed without a proteolytic pre-digestion step in an automated system, preferably a cartridge-based system. In a further aspect, the present invention also provides automated nucleic acid detection methods based on said isolation and/or purification method, as well as buffers and kits to be used in performing said methods.
    Type: Application
    Filed: June 9, 2016
    Publication date: October 11, 2018
    Applicant: Biocartis NV
    Inventors: Geert Meersseman, Klaas DeCanniere