Patents by Inventor Klaus Mueller

Klaus Mueller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200331964
    Abstract: The present invention provides cystobactamides of formula (I): R1—Ar1-L1-Ar2-L2-Ar3-L3-Ar4-L4-Ar5—R2 and the use thereof for the treatment or prophylaxis of bacterial infections.
    Type: Application
    Filed: June 10, 2020
    Publication date: October 22, 2020
    Inventors: Sascha Baumann, Jennifer Herrmann, Kathrin Mohr, Heinrich Steinmetz, Klaus Gerth, Ritesh Raju, Rolf Müller, Rolf W. Hartmann, Mostafa Hamed, Walid A. M. Elgaher, Maria Moreno, Franziska Gille, Liang Liang Wang, Andreas Kirschning, Stephan Huettel
  • Patent number: 10808019
    Abstract: The present invention relates to cytokine fusion proteins and to nucleic acid molecules encoding such cytokine fusion proteins. The present invention further relates to cells, non-human organisms. pharmaceutical compositions and kits comprising the cytokine fusion proteins or the nucleic acid molecules encoding them, as well as to their use as medicaments.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: October 20, 2020
    Assignees: BioNTech RNA Pharmaceuticals GmbH, Universität Stuttgart, TRON-Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz GGMBH
    Inventors: Ugur Sahin, Friederike Gieseke, Ronald Backer, Sebastian Kreiter, Roland Kontermann, Klaus Pfizenmaier, Sina Fellermeier, Dafne Müller
  • Patent number: 10793600
    Abstract: The present invention provides cystobactamides of formula (I) and the use thereof for the treatment or prophylaxis of bacterial infections.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: October 6, 2020
    Assignee: HELMHOLTZ-ZENTRUM FÜR INFEKTIONSFORSCHUNG GMBH
    Inventors: Sascha Baumann, Jennifer Herrmann, Kathrin Mohr, Heinrich Steinmetz, Klaus Gerth, Ritesh Raju, Rolf Müller, Rolf W. Hartmann, Mostafa Hamed, Walid A. M. Elgaher, Maria Moreno, Franziska Gille, Liang Liang Wang, Andreas Kirschning, Stephan Hüttel
  • Patent number: 10759361
    Abstract: The present disclosure relates to a grommet for guiding one or more cables through an opening in a component. The grommet has a first shell element made of a first form-stable plastic and at least partly surrounding the outer circumference of the cable. The grommet also has a second shell element joined to the first shell element and at least partly surrounding the outer circumference of the cable and defining together with the first shell element a guide channel sealed in the circumferential direction of the cable, to guide the cable through the opening in the component. A sealant consisting of a foamed second plastic is introduced into the guide channel to longitudinally seal the grommet against water. The present disclosure also relates to a method for producing such a grommet.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: September 1, 2020
    Assignee: LISA DRAEXLMAIER GmbH
    Inventors: Johann Schwimmbeck, Christian Binder, Klaus Beinhundner, Robert Radu, Silviu Cocis, Enikoe Szabo, Benedikt Müller
  • Publication number: 20200264580
    Abstract: A method for determination of an effective machine use of a machine tool, as well as a machine tool that is configured for this purpose. The machine tool has multiple machine axes in order to move a workpiece and/or a tool. A rotary drive drives the workpiece or the tool in order to remove material. A control unit of the machine tool determines a use duration characteristic parameter (T) and an output power characteristic parameter (L) and determines therefrom a machine use characteristic parameter (M). The use duration characteristic parameter (T) describes a duration during which the workpiece is machined by the tool. The output power characteristic parameter (L) describes the applied or required power in order to effect the material removal. The machine use characteristic parameter (M) is determined by the control unit, such that it can be transmitted to an external unit for further evaluation or processing.
    Type: Application
    Filed: February 14, 2020
    Publication date: August 20, 2020
    Inventors: Simone Müller, Klaus Winkler, Bernd Zapf
  • Publication number: 20200262193
    Abstract: The invention relates to a cylinder (10) which is set up for application of at least one hollow cylinder, the cylinder (10) having a layer structure which comprises in this order, from inside to outside, a base layer (12) or a cylinder core, a first compressible layer (14), a filling layer (16), an interlayer (18), a second compressible layer (20) and an outer layer (22), the outer layer forming a lateral surface of the cylinder. The invention further relates to arrangements comprising at least one such cylinder (10) and further cylinders.
    Type: Application
    Filed: February 18, 2020
    Publication date: August 20, 2020
    Inventors: Martin SCHWIERTZ, Uwe MÜLLER, Klaus BENNINK
  • Publication number: 20200241012
    Abstract: Provided are diagnostic assays and method s of using the diagnostic assays for detecting and quantifying RGMa fragments in a sample. The methods may be used detection of the RGMa fragments to monitoring drug treatment and effectiveness of drug treatment in neurodegenerative diseases.
    Type: Application
    Filed: September 4, 2019
    Publication date: July 30, 2020
    Inventors: Stefan Barghorn, Bernhard Klaus Mueller, Martin Schmidt, Andreas Striebinger
  • Publication number: 20200237838
    Abstract: The present invention relates to the field of oncolytic viruses and in particular to a recombinant rhabdovirus, such as vesicular stomatitis virus encoding in its genome for a CCL21 protein. The invention is further directed to the use of the recombinant virus in the treatment of cancer, and also to methods for producing such viruses.
    Type: Application
    Filed: January 24, 2020
    Publication date: July 30, 2020
    Inventors: Philipp MUELLER, Klaus ERB, Patrik ERLMANN, Tobias Friederike NOLDEN, John Edward PARK, Guido WOLLMANN
  • Patent number: 10729022
    Abstract: A casing for a control unit, including: a connector region, situated on a connector side of the casing, is close-able by two covering hoods, each of the covering hoods including at least one hinge element; and at least two gripping arms, which are configured to at least partially engage around the at least one hinge element of the two covering hoods and to hold it rotationally; in which the two covering hoods are place-able at different positions on the connector region of the casing and are close-able rotationally. Also described are a related covering hood, a control unit, and a commercial vehicle.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: July 28, 2020
    Assignee: KNOR-BREMSE SYSTEME FUER NUTZFAHRZEUGE GMBH
    Inventors: Klaus Lechner, Elena Mueller, Norbert Behrendt
  • Publication number: 20200234976
    Abstract: A method of attaching a semiconductor chip to a lead frame, including A) providing a semiconductor chip, B) applying a solder metal layer sequence on the semiconductor chip, C) providing a lead frame, D) applying a metallization layer sequence on the lead frame, E) applying the semiconductor chip on the lead frame via the solder metal layer sequence and the metallization layer sequence, and F) heating the arrangement produced under E) to attach the semiconductor chip to the lead frame, wherein the solder metal layer sequence includes a first metallic layer including an indium-tin alloy, a barrier layer arranged above the first metallic layer, and a second metallic layer including gold arranged between the barrier layer and the semiconductor chip.
    Type: Application
    Filed: February 28, 2018
    Publication date: July 23, 2020
    Inventors: Mathias Wendt, Klaus Müller, Laurent Tomasini
  • Publication number: 20200209394
    Abstract: A laser scanner and a system with a laser scanner for measuring an environment. The laser scanner includes an optical distance measuring device, a support, a beam steering unit rotatably fixed to the support which rotates around a beam axis of rotation. The beam steering unit includes a mirrored surface which deflects radiation used in the optical distance measurement and an angle encoder for recording angle data. The optical distance measurement is performed by a progressive rotation of the beam steering unit about the beam axis of rotation and the continuous emission of a distance measurement radiation, the emission being made through an outlet area arranged in the direction of the mirrored surface on the support, the receiving optics for receiving radiation are arranged on the support, and wherein the outlet area has a lateral offset with respect to the optical axis of the receiving optics.
    Type: Application
    Filed: November 10, 2016
    Publication date: July 2, 2020
    Applicant: LEICA GEOSYSTEMS AG
    Inventors: Simon MARK, Klaus BEREUTER, Benjamin MÜLLER, Roman STEFFEN, Burkhard BÖCKEM, Jürgen DOLD, Jochen SCHEJA, Lukas HEINZLE, Charles Leopold Elisabeth DUMOULIN
  • Publication number: 20200211997
    Abstract: A method for fastening a semiconductor chip on a substrate and an electronic component are disclosed. In an embodiment a method includes providing a semiconductor chip, applying a solder metal layer sequence on the semiconductor chip, providing a substrate, applying a metallization layer sequence on the substrate, applying the semiconductor chip on the substrate via the solder metal layer sequence and the metallization layer sequence and heating the applied semiconductor chip on the substrate for fastening the semiconductor chip on the substrate. The solder metal layer may include a first metallic layer comprising an indium-tin alloy, a barrier layer arranged above the first metallic layer and a second metallic layer comprising gold arranged between the barrier layer and the semiconductor chip, wherein an amount of substance of the gold in the second metallic layer is greater than an amount of substance of tin in the first metallic layer.
    Type: Application
    Filed: June 6, 2018
    Publication date: July 2, 2020
    Inventors: Klaus Mueller, Andreas Ploessl, Mathias Wendt
  • Publication number: 20200209046
    Abstract: The present disclosure relates to a method for determining fill level of a substance in a container using a measuring device working according to the travel time principle. The measuring device transmits signals to the fill substance and, based on signal fractions reflected back in the container, ascertains an echo curve. The echo curve is transmitted to a superordinate control unit, and an envelope curve enveloping the echo curve is created and transmitted to the superordinate control unit. The echo curve and envelope curve are evaluated by the superordinate control unit. A wanted echo signal of the echo curve and envelope curve is identified. During the determining of the fill level the fill substance and the container are subjected to a current process. Based on information concerning the current process, plausibility of the wanted echo signal is checked and the evaluation is dynamically adapted to the current process.
    Type: Application
    Filed: May 2, 2017
    Publication date: July 2, 2020
    Inventors: Daniel Müller, Klaus Pankratz, Simon Greth
  • Patent number: 10700582
    Abstract: A squirrel-cage rotor of an asynchronous machine has a rotor bar (4) in a rotor stack (1), wherein the bar (4) can be tipped at a tipping point (11, 12, 13) when the bar (4) has not yet been cast. The rotor bar (4) can in this case have a contour on a radial outer face, wherein the bar (4) can also have a channel (27), the opening (29) in said channel being wider than the shoulders (32, 33) of the limbs (30, 31) which form the channel (27).
    Type: Grant
    Filed: September 29, 2011
    Date of Patent: June 30, 2020
    Assignee: SIEMENS AKTIENGESELLSCHAFT
    Inventors: Klaus Büttner, Michael Müller, Norbert Wöhner
  • Publication number: 20200195082
    Abstract: An electric motor includes a rotor having a rotor shaft part and a first shaft part and a second shaft part. The rotor shaft is situated axially between the first and the second shaft parts. The first shaft part includes a first bearing seat and is connected to the rotor shaft part in a torsionally fixed manner, and the second shaft part includes a second bearing seat and is connected to the rotor shaft part in a torsionally fixed manner.
    Type: Application
    Filed: July 16, 2018
    Publication date: June 18, 2020
    Applicant: SEW-EURODRIVE GMBH & CO. KG
    Inventors: Michael STARK, Klaus MÜLLER, Bernhard WINTER
  • Patent number: 10671492
    Abstract: A method for improving integrity and availability of data in a data center is provided. The data center is part of a network of data centers. The data centers in the network are adapted to act as a backup service provider. The method comprises registering backup service profile data of each of the data centers with viable data. The method also comprises accessing a forecast of monitorable events for a region, analyzing the forecast to predict a potential threat, identifying a data center in the regions, and determine a data center within the network of data centers as backup service provider. If more than one suitable backup service providers is identified, determine a best match backup service provider, establishing a backup communication connection, and transferring data from the source data center to the target data center.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: June 2, 2020
    Assignee: International Business Machines Corporation
    Inventors: Joerg Mueller, Stefan Alexander, Alexander Neef, Jan Vorbohle, Michael H. Schlachter, Klaus Rindtorff
  • Publication number: 20200170111
    Abstract: Various embodiments include an electrical assembly comprising: an electronic switching element electrically contacted on an underside and arranged on a flexible first wiring support; wherein the electronic switching element is electrically contacted on an upper side lying opposite the lower side; and a second wiring support arranged lying opposite the first wiring support on the upper side electrical contacting area of the electronic switching element. The first wiring support and the second wiring support each comprise a permanently elastic, electrically insulating, thermally conductive material.
    Type: Application
    Filed: June 19, 2018
    Publication date: May 28, 2020
    Applicant: Siemens Aktiengesellschaft
    Inventors: Rene Blank, Martin Franke, Peter Frühauf, Rüdiger Knofe, Bernd Müller, Stefan Nerreter, Jörg Strogies, Klaus Wilke
  • Publication number: 20200161246
    Abstract: Various embodiments include a semiconductor component comprising: a first carrier part; a second carrier part arranged opposite the first carrier part; a semiconductor element arranged between the first carrier part and the second carrier part; a contact surface arranged on one of the parts; a contact sleeve arranged on one of the carrier parts opposite the contact surface; and a contact pin with, at one axial end, an end face providing an electrical contact connection of the contact surface and, in a region averted from said axial end, a connection region for the connection of the contact pin with the contact sleeve by means of press fitting. At least one of the first carrier part or the second carrier part comprises a printed conductor connected to the contact surface and/or to the contact sleeve.
    Type: Application
    Filed: July 3, 2018
    Publication date: May 21, 2020
    Applicant: Siemens Aktiengesellschaft
    Inventors: Rene Blank, Martin Franke, Peter Frühauf, Rüdiger Knofe, Bernd Müller, Stefan Nerreter, Jörg Strogies, Klaus Wilke
  • Publication number: 20200152532
    Abstract: Various embodiments include an electronic assembly comprising: a first substrate; a second substrate; and a component located between the first substrate and the second substrate. The component is in contact with the first substrate and the second substrate. A gap between the first substrate and the component is bridged with an auxiliary joining material. The first substrate defines a through-hole opening into the gap and sealed by the auxiliary joining material. The first substrate and the second substrate define a cavity closed against the environment.
    Type: Application
    Filed: April 20, 2018
    Publication date: May 14, 2020
    Applicant: Siemens Aktiengesellschaft
    Inventors: Rene Blank, Martin Franke, Peter Frühauf, Rüdiger Knofe, Bernd Müller, Stefan Nerreter, Jörg Strogies, Klaus Wilke
  • Publication number: 20200122450
    Abstract: A tolerance compensation element is for circuit configurations having a DCB (direct copper bonded) substrate and a PCB (printed circuit board). A circuit configuration further includes the tolerance compensation element. A tolerance compensation element is positioned in a targeted manner between the DCB substrate and PCB in a gap A for the contact-connection of components on the DCB substrate via additive manufacturing and is formed so as to close the gap.
    Type: Application
    Filed: June 7, 2018
    Publication date: April 23, 2020
    Applicant: Siemens Aktiengesellschaft
    Inventors: Rene BLANK, Martin FRANKE, Peter FRUEHAUF, Ruediger KNOFE, Bernd MUELLER, Stefan NERRETER, Joerg STROGIES, Klaus WILKE