Abstract: A Breath Actuated Inhaler (10) comprising a canister (14) with a medication dispensed when compressing the canister (14). Compression of the canister (14) is prevented by a mechanism only allowing compression when an air flow is sufficient to ensure dispensing of the medication in the lungs/throat of the person. No latch or blocking mechanism is provided so that any force exerted by the person is, at all times, directed to the canister or preventing mechanism so that when no force is exerted by the user, no force is exerted in the inhaler (10). Prolonged exertion of such force could otherwise cause dimension changes and subsequent uncertainty of the dose size.

Abstract: Certain novel benzothiazoles and benzoxazoles, e.g., 2-(piperazin-1-yl)benzothiazoles and 2-(piperazin-1-yl)benzoxazoles, optionally substituted in the 3 and/or 4 positions of the piperazine rings,! of the general formula (1): having histamine H3 antagonistic activity can be used in pharmaceutical compositions.

Abstract: The present invention relates to devices and methods for automatically determining the use status of medical devices and more particularly to automatic power management based on said use status in electronic medical devices. Specifically, although not exclusively, the invention relates to power management of electronic stethoscopes (1), when such devices are turned on prior to the use of the stethoscope and to problems related to turning on such devices or relating to the time required for such electronic devices to become operable after turning on the device prior to use. Furthermore, the use status determination according to the invention may find use in other devices than stethoscopes, such as injector devices for administering medicaments or inhaling devices.

Abstract: A process for firm joining of two or more pieces of natural casing together using transglutaminase at a low temperature to form desired dimensions, such as length, design and calibre.

Abstract: A dry powder or aerosol inhaler having attached thereto, in a detachable manner, a sound/vibration sensor adapted to sense sound/vibration in the interval of 100-3000 Hz and there from derive a parameter of a flow in a flow path of the inhaler. The sensor does not interfere with the flow path of the inhaler.

Abstract: In well-known electronic stethoscopic transducers the sensitive element is influenced by signals transmitted via the skin, and the rear side is enclosed in a housing to prevent airborne noise from reaching the sensitive element. According to the invention, an improved signal-to-noise ratio is obtained by letting the transducer be a piezoelectric transflexural diaphragm in contact with the skin, the rear side of the diaphragm communicating with the surrounding air via an acoustical network, thereby receiving airborne noise which acts to counteract the influence of noise coming from the skin.

Abstract: A microphone component that may be used in many types of enclosures for making contact with a living body for picking up body sounds. Piezoelectric transflexural diaphragm elements (3, 5, 6) are known; however, they are only useful as microphone elements when the manner of creating electrical contact does not influence their mechanical properties. A microphone component has been developed, which is both rugged and amenable to very inexpensive manufacture. This is obtained using a laminated construction in which a special layer is placed between the piezoelectric transflexural diaphragm element and the electrical interface element.

Abstract: A novel class of substituted homopiperidine, piperidine and pyrrolidine derivatives, methods for their preparation, pharmaceutical compositions comprising them and use thereof in the treatment of disorders related to the histamine H3 receptor. More particularly, the compounds possess histamine H3 receptor antagonistic activity and are thus useful in the treatment of disorders in which a histamine H3 receptor blockade is beneficial.

Abstract: The invention relates to the use of a stethoscope as one part of an interface unit for biological signals. An electroacoustic driver is provided with a signal from e.g. a sound card in a personal computer, and special leak-free coupling means are provided to enable a faithful transmission of the biological signal from e.g. the digital domain in a computer to the ears of a physician used to auscultation—or training to become proficient. The communication of and about physiological signals is remarkably improved with respect to traditional systems.