Patents by Inventor Kohjiro Hashizume

Kohjiro Hashizume has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230225382
    Abstract: An astringency reducing agent including an arabinogalactan which has a molecular weight of from 10,000 to 1,000,000 and a ratio of 1,3-bound galactose to total galactose of 12 mol % or more, as an active ingredient. A method for reducing astringency, including blending the astringency reducing agent into an oral product including an astringent substance.
    Type: Application
    Filed: May 28, 2021
    Publication date: July 20, 2023
    Applicant: KAO CORPORATION
    Inventors: Eri OZEKI, Akihiro TAKAMURA, Kohjiro HASHIZUME, Yoriko OOKI, Tomoya TAKAHASHI
  • Publication number: 20220054641
    Abstract: Provided is an astringency reducing agent having a high astringency reducing effect. The astringency reducing agent has a cold ethanol precipitation product of pear juice as an active ingredient. A method for producing an astringency reducing agent includes placing a mixed liquid comprising pear juice and ethanol at a cold temperature to form a precipitate, and collecting the obtained precipitate.
    Type: Application
    Filed: December 13, 2019
    Publication date: February 24, 2022
    Applicant: KAO CORPORATION
    Inventors: Eri OZEKI, Kohjiro HASHIZUME, Yoriko OOKI
  • Publication number: 20220031790
    Abstract: Provided is a method for producing a red perilla leaf extract which enables to collect rosmarinic acid with a high yield from red perilla leaves to which an acid is added. The method for producing a red perilla leaf extract includes the following step (1): (1) a step of extracting red perilla leaves to which an acid has been added with water under a condition of a pH of from 4.0 to 8.0.
    Type: Application
    Filed: November 26, 2019
    Publication date: February 3, 2022
    Applicant: KAO CORPORATION
    Inventors: Akihiro TAKAMURA, Masazumi IWASHITA, Yuta YAMAMOTO, Kenji YAMAWAKI, Kohjiro HASHIZUME
  • Publication number: 20210300859
    Abstract: The present invention provides a compound that inhibits the activity of TRPV4 and is useful for prevention or amelioration of an overactive bladder, an irritable bowel syndrome, etc.
    Type: Application
    Filed: June 19, 2019
    Publication date: September 30, 2021
    Applicant: KAO CORPORATION
    Inventors: Akihiro TAKAMURA, Naoya KITAMURA, Naoki YAMAMOTO, Kohjiro HASHIZUME
  • Publication number: 20210212959
    Abstract: Provided is a GIP elevation inhibitor useful as, e.g., a pharmaceutical product and food. The GIP elevation inhibitor comprises mannitol as an active ingredient.
    Type: Application
    Filed: May 22, 2019
    Publication date: July 15, 2021
    Applicant: KAO CORPORATION
    Inventors: Akihiro TAKAMURA, Yoshitaka KOGA, Kohjiro HASHIZUME, Takuya MORI
  • Publication number: 20210128664
    Abstract: Provided is a material effective for improving the activity of nerves in the brain or for preventing or ameliorating brain dysfunction. An agent for activating astrocyte glucose metabolism, brain nerve cells activating agent, a brain hypofunction suppressing agent, a brain function improving agent, or an agent for preventing or ameliorating brain dysfunction comprising, as an active ingredient, one or more selected from the group consisting of hydrophobic solvent extracts of tien-cha, rooibos, grape and black tea.
    Type: Application
    Filed: January 15, 2021
    Publication date: May 6, 2021
    Applicant: Kao Corporation
    Inventors: Keiko ISHIDA, Koichi MISAWA, Kohjiro HASHIZUME
  • Patent number: 10925919
    Abstract: Provided is a material effective for improving the activity of nerves in the brain or for preventing or ameliorating brain dysfunction. An agent for activating astrocyte glucose metabolism, brain nerve cells activating agent, a brain hypofunction suppressing agent, a brain function improving agent, or an agent for preventing or ameliorating brain dysfunction comprising, as an active ingredient, one or more selected from the group consisting of hydrophobic solvent extracts of tien-cha, rooibos, grape and black tea.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: February 23, 2021
    Assignee: Kao Corporation
    Inventors: Keiko Ishida, Koichi Misawa, Kohjiro Hashizume
  • Publication number: 20190015469
    Abstract: Provided is a material effective for improving the activity of nerves in the brain or for preventing or ameliorating brain dysfunction. An agent for activating astrocyte glucose metabolism, brain nerve cells activating agent, a brain hypofunction suppressing agent, a brain function improving agent, or an agent for preventing or ameliorating brain dysfunction comprising, as an active ingredient, one or more selected from the group consisting of hydrophobic solvent extracts of tien-cha, rooibos, grape and black tea.
    Type: Application
    Filed: January 4, 2017
    Publication date: January 17, 2019
    Applicant: Kao Corporation
    Inventors: Keiko ISHIDA, Koichi MISAWA, Kohjiro HASHIZUME
  • Patent number: 9827279
    Abstract: A xanthine oxidase inhibitor and a uric acid-producing inhibitor, each containing an extract from at least one member selected from the group consisting of Zanthoxylum bungeanum, Sorghum nervosum, Cuminum cyminum, Rosa centifolia, Pimenta officinalis, Origanum majorana, Psidium guajava, Pimpinella anisum, Olea europaea, Illicium verum, Canavalia gladiata, Hyssopus officinalis, Ribes nigrum, Vaccinium myrtillus, Artemisia princeps and Haematoxylon campechianum L.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: November 28, 2017
    Assignee: Kao Corporation
    Inventors: Naoki Yamamoto, Isamu Watanabe, Atsushi Suzuki, Kohjiro Hashizume
  • Publication number: 20170332655
    Abstract: Provided is a method of producing roasted coffee beans, comprising: a first step of adding water to raw material roasted coffee beans, followed by heating of the resultant; and a second step of subjecting the raw material roasted coffee beans after the first step to supercritical carbon dioxide extraction.
    Type: Application
    Filed: November 11, 2015
    Publication date: November 23, 2017
    Applicant: KAO CORPORATION
    Inventors: Yusuke OKAMURA, Hideo OHMINAMI, Tatsuya KUSAURA, Kohjiro HASHIZUME
  • Publication number: 20170014430
    Abstract: Provided is a cycloartenol-containing composition which can be used as a material for food and beverage, cosmetics, or the like, and has high biological activities. The cycloartenol-containing composition has a cycloartenol content of more than 37% by mass, a 24-methylenecycloartanol content of more than 5% by mass, and a sum content of cycloartenol and 24-methylenecycloartanol of more than 76% by mass, relative to the total mass of sterols.
    Type: Application
    Filed: March 6, 2015
    Publication date: January 19, 2017
    Applicant: KAO CORPORATION
    Inventors: Kohjiro HASHIZUME, Fumiaki OKAHARA
  • Patent number: 9200029
    Abstract: A process for producing triterpene alcohol, comprising sequentially conducting the following steps (A) to (C): (A) subjecting ?-oryzanol to alkaline hydrolysis; (B) mixing the alkaline hydrolysate with a low polarity organic solvent, and extracting triterpene alcohol to obtain a triterpene alcohol-containing low polarity organic solvent; and (C) adding water to the triterpene alcohol-containing low polarity organic solvent thus obtained, removing the low polarity organic solvent, and then melting triterpene alcohol in hot water, followed by cooling.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: December 1, 2015
    Assignees: Kao Corporation, Tsuno Food Industrial Co., Ltd.
    Inventors: Kohjiro Hashizume, Takuo Tsuno, Koji Kato, Hisahiro Morita
  • Patent number: 8501721
    Abstract: A postprandial hyperglycemia-improving agent, the agent is highly safe and exhibits excellent effects of inhibiting the postprandial increase of blood glucose. The postprandial hyperglycemia-improving agent comprises a cycloartenol or a derivative thereof as an active ingredient.
    Type: Grant
    Filed: January 15, 2010
    Date of Patent: August 6, 2013
    Assignee: Kao Corporation
    Inventors: Daisuke Fukuoka, Kohjiro Hashizume, Akira Shimotoyodome
  • Publication number: 20130137883
    Abstract: A process for producing triterpene alcohol, comprising sequentially conducting the following steps (A) to (C): (A) subjecting ?-oryzanol to alkaline hydrolysis; (B) mixing the alkaline hydrolysate with a low polarity organic solvent, and extracting triterpene alcohol to obtain a triterpene alcohol-containing low polarity organic solvent; and (C) adding water to the triterpene alcohol-containing low polarity organic solvent thus obtained, removing the low polarity organic solvent, and then melting triterpene alcohol in hot water, followed by cooling.
    Type: Application
    Filed: August 19, 2011
    Publication date: May 30, 2013
    Applicants: TSUNO FOOD INDUSTRIAL CO., LTD., KAO CORPORATION
    Inventors: Kohjiro Hashizume, Takuo Tsuno, Koji Kato, Hisahiro Morita
  • Publication number: 20120309716
    Abstract: Provided are a motor function improver, an endurance improver, a muscle strength improver, a muscle strength deterioration suppressor, an anti-fatigue agent, a mitochondrial function improver, an energy consumption promoter, and a lipid combustion promoter which contain a sphingomyelin as an active ingredient.
    Type: Application
    Filed: February 2, 2011
    Publication date: December 6, 2012
    Applicant: Kao Corporation
    Inventors: Satoshi Haramizu, Noriyasu Ota, Kohjiro Hashizume, Takatoshi Murase
  • Publication number: 20110275605
    Abstract: A postprandial hyperglycemia-improving agent, the agent is highly safe and exhibits excellent effects of inhibiting the postprandial increase of blood glucose. The postprandial hyperglycemia-improving agent comprises a cycloartenol or a derivative thereof as an active ingredient.
    Type: Application
    Filed: January 15, 2010
    Publication date: November 10, 2011
    Inventors: Daisuke Fukuoka, Kohjiro Hashizume, Akira Shimotoyodome
  • Publication number: 20110268826
    Abstract: A GIP-increase inhibitor, which is useful as a drug or a food, comprising a rice bran extract as an active ingredient.
    Type: Application
    Filed: January 15, 2010
    Publication date: November 3, 2011
    Applicant: Kao Corporation
    Inventors: Daisuke Fukuoka, Kohjiro Hashizume, Akira Shimotoyodome
  • Publication number: 20110165274
    Abstract: A xanthine oxidase inhibitor and a uric acid-producing inhibitor, each containing an extract from at least one member selected from the group consisting of Zanthoxylum bungeanum, Sorghum nervosum, Cuminum cyminum, Rosa centifolia, Pimenta officinalis, Origanum majorana, Psidium guajava, Pimpinella anisum, Olea europaea, Illicium verum, Canavalia gladiata, Hyssopus officinalis, Ribes nigrum, Vaccinium myrtillus, Artemisia princeps and Haematoxylon campechianum L.
    Type: Application
    Filed: July 7, 2009
    Publication date: July 7, 2011
    Applicant: KAO CORORATION
    Inventors: Naoki Yamamoto, Isamu Watanabe, Atsushi Suzuki, Kohjiro Hashizume