Publication number: 20220268790
Abstract: An evaluating method includes an evaluating step of evaluating a pharmacological action of an immune checkpoint inhibitor in a subject to be evaluated, using (i) a concentration value of at least one metabolite among Glu, Arg, Orn, Cit, His, Val, Phe, Tyr, Met, Pro, Asn, Leu, Lys, Thr, Ile, Gln, Ala, Ser, a-ABA, Trp, Gly, AnthA, hAnthA, hIAA, hKyn, hTrp, IAA, ILA, Kyn, KynA, NFKyn, NP, PA, QA, Serot, and XA in blood of the subject to be evaluated, or (ii) a value of a formula calculated using the concentration value and the formula including an explanatory variable to be substituted with the concentration value.
Type:
Application
Filed:
April 27, 2022
Publication date:
August 25, 2022
Applicant:
AJINOMOTO CO., INC.
Inventors:
Sachise KARAKAWA, Tomoyuki TAGAMI, Rumi NISHIMOTO, Shinya KIKUCHI, Akira IMAIZUMI, Koichi AZUMA, Tomoaki HOSHINO, Takaaki TOKITO, Hidenobu ISHII, Norikazu MATSUO