Abstract: A bispecific antibody including a first domain which specifically binds to a mutant calreticulin protein and a second domain which specifically binds to a CD3 antigen. A pharmaceutical composition including the bispecific antibody or a functional fragment thereof. A diagnostic method for a myeloproliferative neoplasm, including detecting a polypeptide in a biological sample with the bispecific antibody.

Abstract: In an ink jet recording sheet including a substrate sheet having a base paper sheet and at least a front polyolefin laminate layer formed on at least a front surface of the base paper sheet, and an ink receiving layer formed on the front polyolefin laminate layer, the surface of the front polyolefin laminate layer has a center-line mean roughness (Ra) of 0.1 to 10 &mgr;m, determined in accordance with JIS B 0601-1982, the ink receiving layer contains a mixture of hydroxypropylmethyl cellulose with polyvinyl pyrrolidone in a mixing weight ratio of 100:10 to 100:150 and has a 75° specular gloss of 30% or more determined in accordance with JIS P 8142-1993.

Abstract: In an ink jet recording sheet including a substrate sheet having a base paper sheet and at least a front polyolefin laminate layer formed on at least a front surface of the base paper sheet, and an ink receiving layer formed on the front polyolefin laminate layer, the surface of the front polyolefin laminate layer has a center-line mean roughness (Ra) of 0.1 to 10 &mgr;m, determined in accordance with JIS B 0601-1982, the ink receiving layer contains a mixture of hydroxypropylmethyl cellulose with polyvinyl pyrrolidone in a mixing weight ratio of 100:10 to 100:150 and has a 75° specular gloss of 30% or more determined in accordance with JIS P 8142-1993.

Abstract: Metal silicide targets are provided for sputtering which have a density of at least 99%, no more than one coarse silicon phase 10 .mu.m or larger in size that appears, per square millimeter, on the sputter surface, and an oxygen content of at most 150 ppm. They are made by a method which comprises finely grinding a synthesized silicide powder, vacuum annealing the finely ground powder in a hot press die without the application of pressure, and thereafter compacting and sintering the compact to a density of at least 99% by hot pressing. Alternatively, the finely ground powder is vacuum annealed as a presintered body at a density ratio of 50 to 75%, and thereafter is compacted and sintered.

Abstract: Silicide targets for sputtering which have an area ratio of silicon phases that appear on the sputter surface of no more than 23%, and a density of at least 99%, with a deformed layer partly removed from the surface to attain a surface roughness of from more than 0.05 .mu.m to 1 .mu.m, preferably with the number of coarse silicon phases at least 10 .mu.m in diameter that appear on the sputter surface being at most 10/mm.sup.2. The reduction of early-stage particle generation, in turn, reduces secondary particle generation, thus realizing the reduction of particle generation at both early stage and stabilized stage. A Si powder having a maximum particle diameter of no more than 20 .mu.m is mixed with a metal powder having a maximum particle diameter of no more than 60 .mu.m, in a rather Si-lower mixing ratio. A silicide powder is synthesized from the mixture and hot pressed, the sintered compact being machined and surface treated for the removal of the deformed layer.

Abstract: Metal silicide targets are provided for sputtering which have a density of at least 99%, no more than one coarse silicon phase 10 .mu.m or larger in size that appears, per square millimeter, on the sputter surface, and an oxygen content of at most 150 ppm. They are made by a method which comprises finely grinding a synthesized silicide powder, vacuum annealing the finely ground powder in a hot press die without the application of pressure, and thereafter compacting and sintering the compact to a density of at least 99% by hot pressing. Alternatively, the finely ground powder is vacuum annealed as a presintered body at a density ratio of 50 to 75%, and thereafter is compacted and sintered.

Abstract: A method of manufacturing metal silicide targets or alloy targets for sputtering use comprises the steps of (a) mechanically alloying silicon and a metal to provide a metal silicide powder or mechanically alloying silicon and a plurality of metal powders to provide an alloy powder, (b) and then pressing the metal silicide powder or alloy powder. The invention also relates to the metal silicide targets or alloy targets so manufactured. In the mechanical alloying step, rapid and fine division and agglomeration of the mixed powder is repeated until the particles of the material powders are finely divided to a submicron level. They form aggregates tens of microns in diameter. The aggregates gradually take an equi-axed shape. Homogenization of the material powder mixture progresses to mixing on the atomic level, until alloying takes place.

Abstract: The present invention provides a method of repairing the joint portions of an existing gas pipe by a repairing device which is movable inside the pipe under remote control. The repairing device can be moved into and out of the gas pipe through a work opening formed in an upper portion of the gas pipe by boring means with gas flowing through the pipe and free of the hazard of gas leakage. This reduces the labor required for forming the work opening to start the repair work and for restoring the work opening portion to complete the repair work, consequently assuring a shortened work period and a reduced cost.

Abstract: Coating of the surface of a pencil barrel with a coat film having a sufficient thickness and smoothness can be well achieved by using a hot-melt polyester as a coating material. The formation of the desired coat film on the pencil barrel can be attained even by only a single coating operation. The coat film of hot-melt polyester formed on the surface of the pencil barrel has an excellent affinity for and an improved adhesion to not only a pencil barrel but also to a lacquer if any lacquer is additionally coated on the polyester-coated pencil barrel. Any organic solvent need not be used, and the coating operation can be completed in an extremely short time. Therefore, the method of the present invention is very advantageous from the viewpoints of prevention of environmental pollution and enhancement of productivity.

Abstract: A hot-melt adhesive comprising a self-curing unsaturated polyester resin having an air-drying functional group and an average polymerization degree of 8 or more has been found to have an excellent heat resistance and a high bonding strength when it is bonding-cured under heat and pressure. If an additive selected from a polymerization initiator, a polymerization promotor and a photosensitizer is incorporated into the present air-drying, self-curing polyester resin, the curing speed is extremely increased to such an extent as cannot be expected from the conventional curing type adhesives. The incorporation of such an additive into the self-curing unsaturated polyester resin is advantageously realized in the form of composite structures of various forms, e.g., a laminate form, a core-in-sheath form and an islands-in-sea form. Such a composite hot-melt adhesive structure is useful for improving a pot life.

Abstract: A process for injection molding a polyester with improved crystallization thereof is described, which comprises incorporating, prior to molding, incorporating in the polyester as a crystallization accelerator a compound containing at least one aromatic ring selected from the group consisting of a benzene ring, a naphthalene ring and an anthracene ring; at least one sulfonic acid alkali metal salt group; and at least one phenolic hydroxy alkali metal salt group.

Abstract: Hydrogen sulfide-containing waste gases whose complete treatment is indispensable from the viewpoint of environmental pollution problem, are purified in two steps consisting of a first step in which the gases are absorbed in an aqueous solution of sodium hydroxide or/and sodium sulfide, and a second step in which sulfuric acid and sulfur dioxide gas are simultaneously introduced into the resulting solution after absorption to deposit sulfur. Further, for recovery of the resulting sulfur, a particular apparatus is provided.