Patents by Inventor Koji Yanai

Koji Yanai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190158638
    Abstract: A transmission device includes a plurality of ports, a first conversion circuit that converts a frame that is input to any one of the plurality of ports and does not include a destination address of a network layer into a packet including the destination address of the network layer, a specification circuit that specifies a port corresponding to the destination address of the network layer of the packet that is converted by the first conversion circuit among the plurality of ports, a second conversion circuit that converts the packet into the frame that does not include the destination address of the network layer, and an output control circuit that causes the frame that is converted by the second conversion circuit to be output from the port that is specified by the specification circuit.
    Type: Application
    Filed: November 15, 2018
    Publication date: May 23, 2019
    Applicant: FUJITSU LIMITED
    Inventors: Koji YANAI, Hideki KANGYU, Norio SAKAI
  • Publication number: 20190141258
    Abstract: An imaging apparatus includes: a finder; a grip portion on a side of a first direction relative to the finder; a touch operation member provided on a rear surface of the imaging apparatus on a side of the first direction relative to the finder, on a side of a second direction relative to the grip portion, the second direction being opposite to the first direction, and on a side of a third direction relative to a center of the imaging apparatus, the third direction being perpendicular to the first direction and being oriented from the center toward the finder; and a control unit configured to control the imaging apparatus so as to execute a first function in accordance with a slide operation in the first direction and to execute a second function in accordance with a slide operation in the second direction.
    Type: Application
    Filed: November 6, 2018
    Publication date: May 9, 2019
    Inventors: Koji Yoshida, Jun Kamiya, Haruhisa Ueda, Takahiro Akimoto, Kimihiro Masuyama, Takuma Iwagami, Hirokazu Izuoka, Takuro Miyajima, Daiyu Ueno, Ryu Wakui, Eriko Sato, Takeshi Kikkawa, Shotaro Yanai, Kenji Yokoyama
  • Patent number: 9771606
    Abstract: The genomic DNA of Streptoverticillium sp. 3-7, which produces UK-2, was analyzed to identify a region expected to be a UK-2 biosynthetic gene cluster. Moreover, by colony hybridization, DNAs in the region were successfully isolated. Further, the DNAs were used to prepare a strain in which the genes present in the region were disrupted. The strain was found not to produce UK-2. It was verified that the genomic region was the UK-2 biosynthetic gene cluster. Furthermore, Streptoverticillium sp. 3-7 was transformed by introduction of a vector in which the isolated UK-2 biosynthetic gene cluster was inserted. It was also found out that the UK-2 productivity by the transformant was improved about 10 to 60 times or more in comparison with that of the parental strain. Moreover, it was revealed that 2 copies of the UK-2 biosynthetic gene cluster were present per cell in these transformants, respectively.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: September 26, 2017
    Assignee: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Koei Kobayashi, Naomi Sumida, Koji Yanai
  • Patent number: 9540617
    Abstract: A modified polynucleotide has a different base sequence in at least one codon from a wild-type base sequence encoding a horseradish peroxidase polypeptide. The usage frequency of the modified codon of the polynucleotide corresponds to the codon usage frequencies of three filamentous fungal species in Humicola, Aspergillus, and Trichoderma. The polynucleotide is capable of expressing the polypeptide to be encoded in a filamentous fungus.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: January 10, 2017
    Assignee: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Fumikazu Yokoyama, Kaoru Okakura, Atsushi Inoue, Koichiro Murashima, Toshiaki Nagasato, Koji Yanai, Akitaka Nakane
  • Publication number: 20160367585
    Abstract: The present invention relates to novel aminoglycoside antibiotics, a process for producing the same, and pharmaceutical use thereof. More specifically, the present invention relates to compounds represented by formula (I), a process for producing the same, and use of the same as antimicrobial agents. wherein R represents amino or hydroxyl.
    Type: Application
    Filed: September 6, 2016
    Publication date: December 22, 2016
    Inventors: Naomi SUMIDA, Koji YANAI, Masato TANI, Takayoshi FUKUSHIMA, Yasumasa OTA, Shuichi GOMI, Akitaka NAKANE
  • Patent number: 9469863
    Abstract: The present invention relates to novel aminoglycoside antibiotics, a process for producing the same, and pharmaceutical use thereof. More specifically, the present invention relates to compounds represented by formula (I), a process for producing the same, and use of the same as antimicrobial agents. wherein R represents amino or hydroxyl.
    Type: Grant
    Filed: December 1, 2008
    Date of Patent: October 18, 2016
    Assignee: MEIJI SEIKA KAISHA, LTD.
    Inventors: Naomi Sumida, Koji Yanai, Masato Tani, Takayoshi Fukushima, Yasumasa Ota, Shuichi Gomi, Akitaka Nakane
  • Publication number: 20160244793
    Abstract: To provide a production method capable of mass production of UK-2 at low cost, the genomic DNA of Streptoverticillium sp. 3-7, which produces UK-2, was analyzed to identify a region expected to be a UK-2 biosynthetic gene cluster. Moreover, by colony hybridization, DNAs in the region were successfully isolated. Further, the DNAs were used to prepare a strain in which the genes present in the region were disrupted. The strain was found not to produce UK-2. It was verified that the genomic region was the UK-2 biosynthetic gene cluster. Furthermore, Streptoverticillium sp. 3-7 was transformed by introduction of a vector in which the isolated UK-2 biosynthetic gene cluster was inserted. It was also found out that the UK-2 productivity by the transformant was improved about 10 to 60 times or more in comparison with that of the parental strain. Moreover, it was revealed that 2 copies of the UK-2 biosynthetic gene cluster were present per cell in these transformants, respectively.
    Type: Application
    Filed: May 10, 2016
    Publication date: August 25, 2016
    Applicant: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Koei KOBAYASHI, Naomi SUMIDA, Koji YANAI
  • Patent number: 9365879
    Abstract: The genomic DNA of Streptoverticillium sp. 3-7, which produces UK-2, was analyzed to identify a region expected to be a UK-2 biosynthetic gene cluster. Moreover, by colony hybridization, DNAs in the region were successfully isolated. Further, the DNAs were used to prepare a strain in which the genes present in the region were disrupted. The strain was found not to produce UK-2. It was verified that the genomic region was the UK-2 biosynthetic gene cluster. Furthermore, Streptoverticillium sp. 3-7 was transformed by introduction of a vector in which the isolated UK-2 biosynthetic gene cluster was inserted. It was also found out that the UK-2 productivity by the transformant was improved about 10 to 60 times or more in comparison with that of the parental strain. Moreover, it was revealed that 2 copies of the UK-2 biosynthetic gene cluster were present per cell in these transformants, respectively.
    Type: Grant
    Filed: July 8, 2013
    Date of Patent: June 14, 2016
    Assignee: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Koei Kobayashi, Naomi Sumida, Koji Yanai
  • Publication number: 20150140574
    Abstract: A modified polynucleotide has a different base sequence in at least one codon from a wild-type base sequence encoding a horseradish peroxidase polypeptide. The usage frequency of the modified codon of the polynucleotide corresponds to the codon usage frequencies of three filamentous fungal species in Humicola, Aspergillus, and Trichoderma. The polynucleotide is capable of expressing the polypeptide to be encoded in a filamentous fungus.
    Type: Application
    Filed: May 30, 2013
    Publication date: May 21, 2015
    Applicant: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Fumikazu Yokoyama, Kaoru Okakura, Atsushi Inoue, Koichiro Murashima, Toshiaki Nagasato, Koji Yanai, Akitaka Nakane
  • Patent number: 8796005
    Abstract: A method for suppressing a reduction in an endoglucanase activity in the presence of a surfactant, characterized by modifying a protein having the endoglucanase activity in which the N-terminus is an amino acid other than pyroglutamic acid, to a protein having the N-terminus of pyroglutamic acid, is disclosed. Further, a modified protein having an endoglucanase activity wherein the N-terminal amino acid is converted into pyroglutamic acid by an amino acid modification, a polynucleotide encoding the protein, an expression vector comprising the polynucleotide, a host cell transformed with the expression vector, and a process for producing the protein by cultivating the host cell, are disclosed.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: August 5, 2014
    Assignee: Meiji Seika Pharma Co., Ltd.
    Inventors: Manabu Watanabe, Koji Yanai, Yumiko Tsuyuki
  • Patent number: 8780564
    Abstract: A solenoid control apparatus includes a resin housing having a solenoid mounting portion, a connector portion, and a circuit board mounting portion in which a circuit board is mounted. Terminals extending from the solenoid mounting portion and the connector portion are soldered to the electrical circuit on the circuit board. The circuit board has a reduced-rigidity portion in its area corresponding to a portion of the resin housing through which the connector portion is connected to the solenoid mounting portion. The reduced-rigidity portion is formed by reducing the amount of material forming the circuit board per unit area, and is more easily deformable than the remaining portion of the circuit board. When the connector portion is thermally deformed, the circuit board is also easily deformable about the reduced-rigidity portion. This reduces stress on the soldered portions.
    Type: Grant
    Filed: January 24, 2012
    Date of Patent: July 15, 2014
    Assignees: Advics Co., Ltd., Denso Corporation
    Inventors: Koji Yanai, Masayuki Hijikata, Takanobu Inagaki, Tetsuya Yoshijima, Toshimasa Miyazaki
  • Patent number: 8697409
    Abstract: Disclosed are a ketoreductase mutant which can be used for an efficient production of daunorubicin derivatives, a DNA encoding the mutant, a transformant prepared by introducing the DNA thereinto to produce a daunorubicin derivative, and a process of producing a daunorubicin derivative using the transformant. The ketoreductase mutant has an amino acid sequence in which one amino acid residue or two or more amino acid residues selected from the group consisting of amino acids located at positions corresponding to the 42nd, 149th, 153rd, 270th, and 306th amino acids in the amino acid sequence of a ketoreductase (EvaE) from a chlororemomycin-producing bacterium (Amycolatopsis orientalis) are substituted with another amino acid residues.
    Type: Grant
    Filed: May 21, 2010
    Date of Patent: April 15, 2014
    Assignee: Meiji Seika Pharma Co., Ltd.
    Inventors: Fusuke Mazuka, Takayoshi Fukushima, Naomi Sumida, Koji Yanai
  • Publication number: 20140051147
    Abstract: A method for suppressing a reduction in an endoglucanase activity in the presence of a surfactant, characterized by modifying a protein having the endoglucanase activity in which the N-terminus is an amino acid other than pyroglutamic acid, to a protein having the N-terminus of pyroglutamic acid, is disclosed. Further, a modified protein having an endoglucanase activity wherein the N-terminal amino acid is converted into pyroglutamic acid by an amino acid modification, a polynucleotide encoding the protein, an expression vector comprising the polynucleotide, a host cell transformed with the expression vector, and a process for producing the protein by cultivating the host cell, are disclosed.
    Type: Application
    Filed: September 19, 2013
    Publication date: February 20, 2014
    Applicant: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Manabu WATANABE, Koji YANAI, Yumiko TSUYUKI
  • Publication number: 20140011203
    Abstract: The genomic DNA of Streptoverticillium sp. 3-7, which produces UK-2, was analyzed to identify a region expected to be a UK-2 biosynthetic gene cluster. Moreover, by colony hybridization, DNAs in the region were successfully isolated. Further, the DNAs were used to prepare a strain in which the genes present in the region were disrupted. The strain was found not to produce UK-2. It was verified that the genomic region was the UK-2 biosynthetic gene cluster. Furthermore, Streptoverticillium sp. 3-7 was transformed by introduction of a vector in which the isolated UK-2 biosynthetic gene cluster was inserted. It was also found out that the UK-2 productivity by the transformant was improved about 10 to 60 times or more in comparison with that of the parental strain. Moreover, it was revealed that 2 copies of the UK-2 biosynthetic gene cluster were present per cell in these transformants, respectively.
    Type: Application
    Filed: July 8, 2013
    Publication date: January 9, 2014
    Inventors: Koei KOBAYASHI, Naomi SUMIDA, Koji YANAI
  • Patent number: 8569033
    Abstract: A method for suppressing a reduction in an endoglucanase activity in the presence of a surfactant, characterized by modifying a protein having the endoglucanase activity in which the N-terminus is an amino acid other than pyroglutamic acid, to a protein having the N-terminus of pyroglutamic acid, is disclosed. Further, a modified protein having an endoglucanase activity wherein the N-terminal amino acid is converted into pyroglutamic acid by an amino acid modification, a polynucleotide encoding the protein, an expression vector comprising the polynucleotide, a host cell transformed with the expression vector, and a process for producing the protein by cultivating the host cell, are disclosed.
    Type: Grant
    Filed: December 7, 2004
    Date of Patent: October 29, 2013
    Assignee: Meiji Seika Pharma Co., Ltd.
    Inventors: Manabu Watanabe, Koji Yanai, Yumiko Tsuyuki
  • Patent number: 8440400
    Abstract: The present invention relates to a process for efficiently amplifying a giant DNA. More particularly, the present invention relates to a process for amplifying DNA in a cell, comprising amplifying the DNA as the target of amplification in the presence of DNAs selected from the following (i), (ii) and (iii): (i) DNA encoding a protein selected from the following 1), 2) and 3): 1) a protein consisting of the amino acid sequence of SEQ ID NO: 1, 2) a protein comprising an amino acid sequence which has a deletion, substitution, insertion or addition of one or more amino acids in the amino acid sequence of SEQ ID NO: 1, and 3) a protein comprising an amino acid sequence which has an identity of 90% or more to the amino acid sequence of SEQ ID NO: 1, (ii) DNA consisting of the nucleotide sequence of SEQ ID NO: 2, and (iii) DNA hybridizing to the nucleotide sequence of SEQ ID NO: 2 under stringent conditions.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: May 14, 2013
    Assignee: Meiji Seika Pharma Co., Ltd.
    Inventors: Takeshi Murakami, Naomi Sumida, Koji Yanai
  • Publication number: 20130116416
    Abstract: Disclosed are a ketoreductase mutant which can be used for an efficient production of daunorubicin derivatives, a DNA encoding the mutant, a transformant prepared by introducing the DNA thereinto to produce a daunorubicin derivative, and a process of producing a daunorubicin derivative using the transformant. The ketoreductase mutant has an amino acid sequence in which one amino acid residue or two or more amino acid residues selected from the group consisting of amino acids located at positions corresponding to the 42nd, 149th, 153rd, 270th, and 306th amino acids in the amino acid sequence of a ketoreductase (EvaE) from a chlororemomycin-producing bacterium (Amycolatopsis orientalis) are substituted with another amino acid residues.
    Type: Application
    Filed: May 21, 2010
    Publication date: May 9, 2013
    Applicant: MEIJI SEIKA PHARMA, CO., LTD.
    Inventors: Fusuke Mazuka, Takayoshi Fukushima, Naomi Sumida, Koji Yanai
  • Patent number: 8383392
    Abstract: Disclosed is a transformant prepared by introducing a ketoreductase gene involved in the biosynthesis of L-epivancosamine into an actinobacterium originally capable of producing daunorubicin. Also disclosed is a process of efficiently producing a non-natural daunorubicin derivative using the transformant. The transformant is capable of efficiently producing a non-natural daunorubicin derivative such as epidaunorubicin.
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: February 26, 2013
    Assignee: Meiji Seika Pharma Co., Ltd.
    Inventors: Naomi Sumida, Manabu Watanabe, Koji Yanai
  • Publication number: 20120267946
    Abstract: An annular seal member includes: an annular base part; and a seal edge, which is provided on both end faces of the annular base part to protrude in opposite directions, wherein the seal edge is configured to closely contact with a opposing face of a seal target such that an inner periphery side of the base part and an outer periphery side of the base part are fluid-tightly partitioned, wherein a plurality of the seal edges is provided in parallel with each other in at least one area of the base part, and wherein the number of the seal edges in the at least one area of the base part is larger than the number of the seal edges in the other area of the base part.
    Type: Application
    Filed: April 25, 2012
    Publication date: October 25, 2012
    Applicants: DENSO CORPORATION, ADVICS CO., LTD.
    Inventors: Masato OGAWA, Ayumi YAMAMURA, Masayuki HIJIKATA, Koji YANAI
  • Publication number: 20120195007
    Abstract: A solenoid control apparatus includes a resin housing having a solenoid mounting portion, a connector portion, and a circuit board mounting portion in which a circuit board is mounted. Terminals extending from the solenoid mounting portion and the connector portion are soldered to the electrical circuit on the circuit board. The circuit board has a reduced-rigidity portion in its area corresponding to a portion of the resin housing through which the connector portion is connected to the solenoid mounting portion. The reduced-rigidity portion is formed by reducing the amount of material forming the circuit board per unit area, and is more easily deformable than the remaining portion of the circuit board. When the connector portion is thermally deformed, the circuit board is also easily deformable about the reduced-rigidity portion. This reduces stress on the soldered portions.
    Type: Application
    Filed: January 24, 2012
    Publication date: August 2, 2012
    Applicants: DENSO CORPORATION, ADVICS CO., LTD.
    Inventors: Koji YANAI, Masayuki Hijikata, Takanobu Inagaki, Tetsuya Yoshijima, Toshimasa Miyazaki