Patents by Inventor Konstantin Khrapko

Konstantin Khrapko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR HIGH-FIDELITY SEQUENCE ANALYSIS OF INDIVIDUAL LONG AND ULTRALONG NUCLEIC ACID MOLECULES
    Publication number: 20230193353
    Abstract: Disclosed are compositions and methods related to the use of plurality of reverse transcriptase primers, unique molecular identifiers (UMIs), and/or spiky primers with unique junction identifiers to improve the sequencing and amplifications methods. In some embodiments, the disclosed methods can identify sequencing errors and PCR-jumping errors.
    Type: Application
    Filed: May 7, 2021
    Publication date: June 22, 2023
    Inventors: Zoe Fleischmann, Konstantin Khrapko, Dori C. Woods, Jonathan L. Tilly
  • Sequencing Methods
    Publication number: 20180371544
    Abstract: Disclosed are compositions and methods related to the use of unique molecular identifiers (UMIs) to improve the error-correction capability of third generation sequencing and similar approaches that involve high precision reading of long segments of single DNA molecules.
    Type: Application
    Filed: December 30, 2016
    Publication date: December 27, 2018
    Inventors: Konstantin Khrapko, Sfia Annis, Jonathan Lee Tilly, Dori Cousins Woods, Slava Epstein