Patents by Inventor Konstantinos Gavardinas

Konstantinos Gavardinas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8658638
    Abstract: The present invention provides a compound of the formula: or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising Compound (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly congestive heart failure, hypertension, diabetic nephropathy, or chronic kidney disease, comprising administering Compound (I), or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: February 25, 2014
    Assignee: Eli Lilly and Company
    Inventors: David Andrew Coates, Konstantinos Gavardinas, Prabhakar Kondaji Jadhav
  • Patent number: 8227468
    Abstract: The present invention provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof. Also, the present invention provides a pharmaceutical composition comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof with a pharmaceutically acceptable diluent or carrier. The present invention further provides methods for treating abdominal aortic aneurysm, plaque instability, atherosclerosis, or autoimmune disorders such as rheumatoid arthritis, psoriasis, and lupus comprising administering a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising a compound of Formula (I) or pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
    Type: Grant
    Filed: October 14, 2011
    Date of Patent: July 24, 2012
    Assignee: Eli Lilly and Company
    Inventors: Gary G. Deng, Konstantinos Gavardinas, Prabhakar Kondaji Jadhav, Euibong Jemes Kim, Matthew Allen Schiffler
  • Publication number: 20120095020
    Abstract: The present invention provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof. Also, the present invention provides a pharmaceutical composition comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof with a pharmaceutically acceptable diluent or carrier. The present invention further provides methods for treating abdominal aortic aneurysm, plaque instability, atherosclerosis, or autoimmune disorders such as rheumatoid arthritis, psoriasis, and lupus comprising administering a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising a compound of Formula (I) or pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
    Type: Application
    Filed: October 14, 2011
    Publication date: April 19, 2012
    Applicant: Eli Lilly and Company
    Inventors: Gary G. DENG, Konstantinos GAVARDINAS, Prabhakar Kondaji JADHAV, Euibong Jemes KIM, Matthew Allen SCHIFFLER
  • Publication number: 20110312954
    Abstract: The present invention provides a compound of the formula: Compound (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising Compound (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly congestive heart failure, hypertension, diabetic nephropathy, or chronic kidney disease, comprising administering Compound (I), or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 4, 2010
    Publication date: December 22, 2011
    Applicant: ELI LILLY AND COMPANY
    Inventors: David Andrew Coates, Konstantinos Gavardinas, Prabhakar Kondaji Jadhav
  • Patent number: 7994164
    Abstract: The present invention provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly congestive heart failure, hypertension, diabetic nephropathy, or chronic kidney disease, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: August 9, 2011
    Assignee: Eli Lilly and Company
    Inventors: Konstantinos Gavardinas, Prabhakar Kondaji Jadhav
  • Patent number: 7968587
    Abstract: The present invention provides a compound of the formula: Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly reduced bones mass, osteoporosis, osteopenia, or reduced muscle mass or strength, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt thereof. X-17142.
    Type: Grant
    Filed: November 6, 2007
    Date of Patent: June 28, 2011
    Assignee: Eli Lilly and Company
    Inventors: Konstantinos Gavardinas, Jonathan Edward Green, Prabhakar Kondaji Jadhav, Donald Paul Matthews
  • Patent number: 7807691
    Abstract: The present invention provides a compound of the Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly frailty, osteoporosis, osteopenia, and male and female sexual dysfunction comprising administering to a patient in need thereof an effective amount of a compound of Formula (I).
    Type: Grant
    Filed: May 10, 2006
    Date of Patent: October 5, 2010
    Assignee: Eli Lilly and Company
    Inventors: Konstantinos Gavardinas, Prabhakar Kondaji Jadhav, Douglas Richard Stack
  • Patent number: 7803814
    Abstract: The present invention provides a compound of the formula (I): or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly congestive heart disease, hypertension, rheumatoid arthritis or inflammation, comprising administering to a patient in thereof an effective amount of a compound of Formula (I).
    Type: Grant
    Filed: December 8, 2004
    Date of Patent: September 28, 2010
    Assignee: Eli Lilly and Company
    Inventors: Konstantinos Gavardinas, Jonathan Edward Green, Prabhakar Kondaji Jadhav, Donald Paul Matthews
  • Patent number: 7728150
    Abstract: The present invention provides a compound of the formula: Formula (I); or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising an effective amount of a compound of Formula I in combination with a suitable carrier, diluent, or excipient, and methods for treating physiological disorders, particularly congestive heart disease, hypertension, and atherosclerosis, comprising administering to a patient in thereof an effective amount of a compound of Formula I.
    Type: Grant
    Filed: February 18, 2005
    Date of Patent: June 1, 2010
    Assignee: Eli Lilly and Company
    Inventors: Konstantinos Gavardinas, Prabhakar Kondaji Jadhav, Minmin Wang
  • Publication number: 20100069404
    Abstract: The present invention provides a compound of the formula: Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly reduced bones mass, osteoporosis, osteopenia, or reduced muscle mass or strength, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt thereof. X-17142.
    Type: Application
    Filed: November 6, 2007
    Publication date: March 18, 2010
    Inventors: Konstantinos Gavardinas, Jonathan Edward Green, Prabhakar Kondaji Jadhav, Donald Paul Matthews
  • Publication number: 20090163472
    Abstract: The present invention provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly congestive heart failure, hypertension, diabetic nephropathy, or chronic kidney disease, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 9, 2008
    Publication date: June 25, 2009
    Inventors: Konstantinos GAVARDINAS, Prabhakar Kondaji Jadhav
  • Publication number: 20080176864
    Abstract: The present invention provides a compound of the Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly frailty, osteoporosis, osteopenia, and male and female sexual dysfunction comprising administering to a patient in need thereof an effective amount of a compound of Formula (I).
    Type: Application
    Filed: May 10, 2006
    Publication date: July 24, 2008
    Inventors: Konstantinos Gavardinas, Prabhakar Kondaji Jadhav, Douglas Richard Stack, Ian Roger Clemens
  • Publication number: 20070185161
    Abstract: The present invention provides a compound of the formula: Formula (I); or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising an effective amount of a compound of Formula I in combination with a suitable carrier, diluent, or excipient, and methods for treating physiological disorders, particularly congestive heart disease, hypertension, and atherosclerosis, comprising administering to a patient in thereof an effective amount of a compound of Formula I.
    Type: Application
    Filed: February 18, 2005
    Publication date: August 9, 2007
    Inventors: Konstantinos Gavardinas, Prabhakar Jadhav, Minmin Wang
  • Publication number: 20070037788
    Abstract: The present invention provides a compound of the formula (I): or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly congestive heart disease, hypertension, rheumatoid arthritis or inflammation, comprising administering to a patient in thereof an effective amount of a compound of Formula (I).
    Type: Application
    Filed: December 8, 2004
    Publication date: February 15, 2007
    Applicant: Eli Lilly and Company
    Inventors: Konstantinos Gavardinas, Jonathan Green, Prabhakar Jadhav, Donald Matthews
  • Publication number: 20060235222
    Abstract: The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising an effective amount of a compound of Formula I in combination with a suitable carrier, diluent, or excipient, and methods for treating physiological disorders, particularly congestive heart disease, comprising administering to a patient in thereof an effective amount of a compound of Formula I.
    Type: Application
    Filed: January 20, 2004
    Publication date: October 19, 2006
    Applicant: ELI LILLY AND COMPANY
    Inventors: Michael Bell, Konstantinos Gavardinas, Douglas Gernert, Timothy Grese, Prabhakar Jadhav, Peter Lander, Mitchell Steinberg