Patents by Inventor Kouji Oohashi

Kouji Oohashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120101046
    Abstract: Intravitreal administration of a JNK-inhibitory peptide less than 150 amino acids in length, containing at least one D-amino acid, and having (a) a JNK-inhibitory sequence of at least any of SEQ ID NO: 1 and SEQ ID NO: 2, and (b) a transport sequence of at least any of SEQ ID NO: 3 and SEQ ID NO: 4 suppressed spermidine-induced retinal pigment epithelial damage, tunicamycin-induced photoreceptor cell damage, and laser-induced choroidal neovascularization. Thus, the JNK-inhibitory peptide of the present invention is useful for prophylaxis or therapy of a retinal disease. By the use of this JNK-inhibitory peptide, a drug and a method are provided which are capable of preventing or treating a retinal disease even by topical administration to the eye, and use of the JKN-inhibitory peptide for manufacturing the drug is also provided.
    Type: Application
    Filed: March 25, 2010
    Publication date: April 26, 2012
    Applicant: SANTEN PHARMACEUTICAL CO., LTD.
    Inventors: Shin-ichiro Hirai, Tokiyoshi Matsushita, Yukie Fujita, Hiroaki Kurashima, Kouji Oohashi
  • Publication number: 20110160267
    Abstract: A method for treating diabetic retinopathy involving topically administering to an eye of a patient a pharmacologically effective amount of a compound represented by the following formula [II] or a salt thereof: wherein R1, R2 and R3 are the same or different and represent a hydrogen atom or an alkyl group, or R1 and R3 may be joined together to form a ring having one or more double bonds.
    Type: Application
    Filed: March 4, 2011
    Publication date: June 30, 2011
    Applicant: SANTEN PHARMACEUTICAL CO., LTD.
    Inventors: Kouji Oohashi, Reina Doi, Tatsuji Kurose, Masaaki Kageyama
  • Publication number: 20110160262
    Abstract: A method for treating retinal vein occlusion involving administering to a patient a pharmacologically effective amount of a compound represented by the following formula (II) or a salt thereof: wherein R1, R2 and R3 are the same or different and represent a hydrogen atom or an alkyl group, or R1 and R3 may be joined together to form a ring having one or more double bonds.
    Type: Application
    Filed: February 28, 2011
    Publication date: June 30, 2011
    Applicant: SANTEN PHARMACEUTICAL CO., LTD.
    Inventors: Kouji Oohashi, Reina Doi, Tatsuji Kurose, Masaaki Kageyama
  • Publication number: 20090253765
    Abstract: An object of the present invention is to provide an angiogenesis inhibitor. The angiogenesis inhibitor according to the present invention contains a compound represented by the following general formula [I] or a salt thereof as an active ingredient. In the formula, the ring A represents a benzene ring or a naphthalene ring; X represents a single bond, an alkylene group or —CH2COOCH2—; Y represents an oxygen atom or N(R6); R1, R2 and R3 are the same or different and represent a hydrogen atom or an alkyl group, or R1 and R3 may be joined together to form a ring having one or more double bonds; R4 and R5 are the same or different and represent a hydrogen atom or an alkyl group; and R6 represents a hydrogen atom or an alkyl group.
    Type: Application
    Filed: May 17, 2006
    Publication date: October 8, 2009
    Applicant: Santen Pharmaceutical Co., Ltd.
    Inventors: Kouji Oohashi, Reina Doi, Tatsuji Kurose, Masaaki Kageyama
  • Publication number: 20090088472
    Abstract: An object of the present invention is to provide a protective agent for a neuronal cell. The protective agent for a neuronal cell according to the present invention contains a compound represented by the following general formula [I] or a salt thereof as an active ingredient. In the formula, R1, R2 and R3 are the same or different and represent a hydrogen atom or an alkyl group, or R1 and R3 may be joined together to form a ring having one or more double bonds.
    Type: Application
    Filed: May 17, 2006
    Publication date: April 2, 2009
    Inventors: Kouji Oohashi, Reina Doi, Masaaki Kageyama
  • Patent number: 5513091
    Abstract: A voltage transforming circuit comprises a constant-voltage regulator circuit for receiving a first voltage from a first voltage source and outputting a second voltage having the same polarity as the first voltage and a predetermined absolute value lower than the same, a step-up circuit, having a plurality of output terminals, for receiving the second voltage and a first synchronization signal, the step-up circuit stepping up the absolute value of the second voltage and controlling the operation of charging capacitors, thereby outputting from the output terminals a plurality of stepped-up voltages of the same polarity having absolute values higher than the second voltage, a level shifter circuit for receiving a second synchronization signal which uses the first voltage as one of logic levels, and receiving that one of the stepped-up voltages which has a highest absolute value higher than that of the first voltage, the level shifter circuit shifting the voltage of the one of logic levels to the highest absolut
    Type: Grant
    Filed: March 23, 1995
    Date of Patent: April 30, 1996
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Hideaki Uchida, Kouji Oohashi