Abstract: A method for playing a local ringback tone is disclosed. A second party device is called from a calling party device. An alert message indicating that the calling party device is to play a network ringback tone is received. It is determined whether to play a pre-stored local ringback tone instead of the network ringback tone. The local ringback tone or the network ringback tone is played based on the determination. At any time before call connection or call release, the local ringback tone and the network ringback tone are switched between based on user input.

Abstract: The present invention relates to pharmaceutical dosage forms of an antidepressant. More particularly, the present invention relates to pharmaceutical dosage forms of Escitalopram oxalate. The present invention also relates to a process for the preparation of pharmaceutical dosage forms of Escitalopram oxalate.

Abstract: The invention provides a method of determining the prognosis of cancer in a subject. The method comprises (a) obtaining a sample from the subject, (b) analyzing the sample for the expression level of a carboxypeptidase E (CPE) splice variant, and (c) correlating the expression level in the sample with the prognosis of cancer in the subject. The invention further provides a method of diagnosing cancer, methods of treatment, kits for detecting mRNA expression of a CPE-?N, and inhibitors of CPE-?N and compositions thereof.

Abstract: The present invention relates to novel polymorphic forms of N-[2-(diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl-2,4-dimethyl-1H-pyrrole-3-carboxamide-Sunitinib base (I). The present invention also relates to methods of preparing such polymorphic crystals.

Abstract: The present invention relates to an improved process for the preparation of N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide—Sunitinib base of formula (I) and its pharmaceutically acceptable malate salt of formula (I(a)).

Abstract: A filter cartridge has a shell defining an upper portion with an upper interior volume and a lower portion with a lower interior volume. The cartridge is for use in gravity-fed water treatment systems have an upper untreated supply and a lower filtered container. A hydrophilic porous particulate carbon powder block filter in a polymeric binder is disposed in the cartridge. The filter has a central opening and is open on both ends. The top end of the block is fitted with an air vent tube. The lower end of the block is fitted into a rubber gasket to direct water flow into the lower container. As water flow through the filter cartridge, air is vented through the block filter central opening and out through the vent tube.

Abstract: A contact sharing system is described herein that allows multiple people to share their address books of contact information so that a person can search for contact information among the address books of the person's existing contacts in addition to any publicly available searchable sources of contact information. Because at least one of a person's contacts is likely to have contact information for the person or business that the person is trying to reach, searching the contacts of contacts is more likely to produce relevant search results than searching anonymous or public sources of contact information alone. Thus, the contact sharing system makes it easier for people to find contact information for people and businesses that they are trying to reach.

Abstract: A web based method and system for assessing client portfolio is disclosed. Assessing client portfolio of the client comprises checking whether the client portfolio maps to the application needs of the client. An assessment model is generated to assess the client portfolio. Inputs regarding business domains and strategy of the client is received and based on the inputs the assessment model is generated. Thereafter assessment score of the client is calculated based on the client inputs and modifications for the assessment model. If the assessment score of the client is below a threshold limit, the client is prompted to update his or her client portfolio.

Abstract: The invention relates to a method of preparation and use of a polypeptide vaccine formulation for prevention and control of Staphylococci mediated infections in human, bovine and other mammals, using recombinant DNA technology.

Abstract: A monitoring system provided according to an aspect of the present invention enables a user to specify multiple resource elements as a resource pool, and view various aggregate information (e.g., sum, average) for attributes of interest for all the resource elements together. Such a feature is particularly useful in distributed environments where multiple independent resource elements need to be viewed as a single resource pool. The user is provided the flexibility to select the specific resource elements to be included in the resource pool.

Abstract: The present invention relates to a composition comprising a viral antigen, a first protein and a second protein. Optionally, the composition also comprises three different disaccharaides, or, optionally, the composition comprises a primary sugar and at least one, preferably two secondary sugars. The present invention also relates to the use of a viral antigen, a first protein and a second protein for the manufacture of a composition, preferably a vaccine. The present invention furthermore relates to a method of treatment or prevention of virus associates diseases in humans. Moreover, the present invention relates to a method of adapting a virus to a suitable cell-line. The invention is also useful for the production of virus suspensions suitable for making stable, live/inactivated, monovalent and/or polyvalent, liquid/lyophilized rotavirus vaccine compositions for oral and/or nasal or any other suitable route of administration in human.

Abstract: A method of elliptic curve encryption includes, (a) selecting an elliptic curve Ep (a,b) of the form y2=x3+ax+b mod (p) wherein a and b are non-negative integers less than p satisfying the formula 4 a3+27b2 mod (p) not equal to 0; (b) generating a large 160 bit random number by a method of concatenation of a number of smaller random numbers; (c) generating a well hidden point G (x,y) on the elliptic curve Ep (a,b) by scalar multiplication of a point B (x,y) on the elliptic curve with a large random integer which further includes the steps: (i) converting the large random integer into a series of powers of 231; (ii) converting each coefficient of 231 obtained from above step into a binary series; (iii) multiplication of binary series obtained from steps (i) and (ii) above with the point B (x,y) on the elliptic curve; (d) generating a private key nA (of about >=160 bit length); (e) generating a public key PA (x,y) given by the formula PA (x,y)=(nA?G (x,y)) mod (p); (f) encrypting the input message MSG; (g) d

Abstract: New thrombolytic protein molecules such as recombinant staphylokinase or streptokinase, urokinase, tissue plasminogen activator and the like, and suitable variants thereof, for targeting to brain tissue or any other tissue by either fusing to, or by synthesizing the candidate thrombolytic molecule(s) with a protein sequence comprising a strong amphipathic alpha helix containing protein transduction domain. Thrombolytic protein molecule(s) so engineered with the protein transduction domain is useful for enhanced uptake of such protein thrombolytic molecule(s) across the cell membranes and tissues including the blood brain barrier and find their use in the treatment of vascular thrombosis including cerebrovascular disorders caused by cerebral thrombosis or cerebral haemorrhage when used a as a therapeutic. The design and processes for cloning, expression, purification and protein transduction of such proteins across cell membranes.

Abstract: The subject invention relates to a process for the synthesis of highly active binary metal fluoride system for the fluorination of aromatic compounds. Fluorinated aromatic compounds are valuable synthons for the chemical synthesis of pharmaceutical drugs and novel polymers. Fluorobenzene is used to control carbon content in steel manufacturing, is an intermediate for pharmaceuticals, pesticides and other organic compounds. Fluorobenzene is typically produced by the reaction of aniline and sodium nitrite in the presence of hydrogen fluoride. The present invention relates to a process for the synthesis of highly active binary metal fluoride system consists of copper (II) fluoride and aluminum (III) fluoride for the fluorination of aromatic compounds in gas phase and recycling of the reagent, in situ, using O2 and HF.

Abstract: A method for continuous extrusion of activated carbon tubular shapes used in a water filtration device and process for making same. A mixture of primarily activated carbon and polymeric binder is gravity fed into an extruder barrel through a slide to facilitate uniform feed. The binder is surface charged by a plasma process to attach to the carbon with a weak force. The barrel is heated by induction heating to provide high and constant heat source. A desired porosity in the carbon profile is achieved by varying the mesh size of the carbon and binder along with changing the pitch in the screw.

Abstract: A multi-stage water purification device includes an untreated water compartment having an untreated water inlet and a treated water compartment formed from a resilient material. The compartments are segregated from one another. An outlet is in flow communication with the treated water compartment. A first unidirectional valve is disposed between the treated water compartment and the outlet and is configure to permit flow out of the treated water compartment only. A filter is disposed between the untreated water compartment and the treated water compartment. The untreated water flows through the filter to produce treated water. A second unidirectional flow valve is positioned at the discharge of the filter and is configured to permit flow out of the filter and into the treated water compartment only. Water is introduced into the untreated water compartment and the treated water compartment is deformed to reduce the volume therein.

Abstract: The present invention describes method of preparation and use of polypeptide vaccine formulation for prevention and control of Staphylococci mediated infections in human, bovine and other mammals, using recombinant DNA technology.

Abstract: A universal water purifier unitary assembly device comprising a device housing unit support structure, a manually operated air pump, a force-fed water filter cartridge of multiple separable stages and a separable sealing means to seal the junction and opening between said universal water purifier unitary assembly device housing unit support structure and water container of water to be filtered wherein junction and opening between of said water purifier unitary assembly device housing unit support structure and said water container is sealed to retain compressed air. Water of said container is filtered, treated and used as needed on demand as in a group environment wherein individual use and consumption of purified water is relevant. The water is stored in a container, being pumped from the container by compressed air provided by an air pump.

Abstract: A composition for treating a wound, wherein the composition can comprise therapeutically effective amount of an epidermal growth factor and a physiologically acceptable agent, wherein the physiologically acceptable agent comprises at least one of a stabilizer, a preservative, a thickening agent, carrier/diluent, and optionally pH regulating agent and humectant.

Abstract: A bonding method for a filtration unit for bonding a polymeric end cap to a porous filter element body includes providing a polymeric end cap of a filtration unit, providing a porous filter element body and positioning a hot melt adhesive element and a metal element between the porous filter element body and the end cap. A pressure is applied between the porous filter element body and the end cap and an electromagnetic field is induced at the metal element. The hot melt adhesive is melted and flows between the end cap and the porous filter element body and a bond is formed between the porous filter element body and the end cap.