Patents by Inventor Krishnan Chari

Krishnan Chari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050106712
    Abstract: A coating composition for making a protein microarray, the composition comprising a gelling agent or a precursor to a gelling agent and microspheres; the microspheres containing a dye represented by Formula (I): wherein: R1 and R2 independently reprresent substituted or unsubstituted alkyl, aryl, carbocyclic ring, heterocyclic ring, or amino; and R3 represents H, alkylamino, dialkylamino, hydroxy, or alkoxy.
    Type: Application
    Filed: November 14, 2003
    Publication date: May 19, 2005
    Inventors: Krishnan Chari, Tiecheng Qiao, Donald Diehl, Samuel Chen
  • Publication number: 20050072961
    Abstract: The invention relates to a novel class of compounds useful as chiral dopants, which compounds are available in both enantiomeric forms. Another aspect of the invention relates to such compounds having a enantiomeric excess of one enantiomeric form, which are useful in liquid crystal formulations. Such formulations are advantageous in displays and various other products.
    Type: Application
    Filed: August 29, 2003
    Publication date: April 7, 2005
    Inventors: Thomas Welter, Krishnan Chari
  • Publication number: 20050019804
    Abstract: An element containing an array of microspheres on a support is described, and a method of making the element, wherein the method includes coating a support with a coating composition to form a receiving layer with a modifiable elastic modulus; coating on the receiving layer a dispersion of microspheres in a fluid suspension; modifying the modulus of the receiving layer to allow the microspheres to partially submerge into the receiving layer; removing the fluid suspension from the receiving layer; and fixing the microspheres in the receiving layer so that the element can withstand wet processing.
    Type: Application
    Filed: June 15, 2004
    Publication date: January 27, 2005
    Inventors: Krishnan Chari, Zhanjun Gao, Joseph Sedita, Ramasubramaniam Hanumanthu, Charles Lusignan
  • Publication number: 20050019954
    Abstract: A color coded bead for use in a microarray for detecting target analytes, the bead comprising: a photochromic compound in a medium, the bead having a receptor molecule on its surface; wherein the photochromic compound confers on the bead a distinct optical signature; and wherein the receptor molecule is capable of binding to a target analyte.
    Type: Application
    Filed: July 23, 2003
    Publication date: January 27, 2005
    Inventors: Deepak Shukla, Krishnan Chari, Samuel Chen
  • Publication number: 20050019745
    Abstract: A method for making an element containing an array of microspheres on a support, the method comprising the steps of: coating a support with a coating composition to form a receiving layer with a modifiable elastic modulus; coating on the receiving layer a dispersion of microspheres in a carrier fluid; modifying the modulus to allow the microspheres to partially submerge into the intermediate layer; removing the fluid medium from the suspension of microspheres; and fixing the microspheres on the receiving layer so that the element can withstand wet processing.
    Type: Application
    Filed: July 23, 2003
    Publication date: January 27, 2005
    Inventors: Krishnan Chari, Zhanjun Gao, Joseph Sedita, Ramasubramaniam Hanumanthu, Charles Lusignan
  • Publication number: 20040263848
    Abstract: A method of determining one or more color characteristics of a colored microsphere comprising: providing a microarray of microspheres, at least one of which has a color characteristic; capturing the microarray with an electronic color image sensor assembly having a matrix of pixels to produce an electronic microarray image; detecting the location of a microsphere within the captured microarray image; and identifying a color characteristic of the detected microsphere.
    Type: Application
    Filed: June 26, 2003
    Publication date: December 30, 2004
    Inventors: Samuel Chen, Krishnan Chari, Martin C. Kaplan, Douglas L. Vizard, Joaquin Calcines
  • Publication number: 20040265905
    Abstract: A method of determining one or more color characteristics of a colored microsphere comprising: providing a microarray of microspheres, including at least one colored microsphere which has a color characteristic; producing a magnified optical image of individual microspheres of the microarray; locating a microsphere in the aperture of a spectrometer to confine the color region of interest of the located microsphere in order to determine one or more color characteristics thereof; and determining one or more color characteristics of the located microsphere by means of the spectrometer.
    Type: Application
    Filed: June 26, 2003
    Publication date: December 30, 2004
    Inventors: Samuel Chen, Anthony E. Taddei, Joaquin Calcines, Krishnan Chari, Martin C. Kaplan, Douglas L. Vizard
  • Patent number: 6797393
    Abstract: A gelatin-based substrate for fabricating protein arrays, the substrate containing: gelatin and a trifunctional compound A—L—B; wherein A is a functional group capable of interacting with the gelatin; L is a linking group capable of interacting with A and with B; and B is a functional group capable of interacting with a protein capture agent. A may be the same or different from B.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: September 28, 2004
    Assignee: Eastman Kodak Company
    Inventors: Tiecheng A. Qiao, Krishnan Chari, Thomas L. Penner, Zhihao Yang
  • Publication number: 20030224361
    Abstract: A method of making a microarray comprising the steps of: providing a support; coating on the support a fluid composition containing microspheres and gelatin; immobilizing the microspheres in the gelatin coating; partially digesting the gelatin with an enzyme to expose surfaces of the microspheres; and removing the enzyme and digested gelatin from the coating.
    Type: Application
    Filed: June 3, 2002
    Publication date: December 4, 2003
    Applicant: Eastman Kodak Company
    Inventors: Tiecheng A. Qiao, Krishnan Chari, Robledo O. Gutierrez
  • Patent number: 6649312
    Abstract: Disclosed is light sensitive element comprising a support, at least one light sensitive silver halide emulsion layer, and a micro-bead layer comprising micro-beads a wherein the quantity of binder in the micro-bead layer is such that the micro-beads are not fully enclosed by the binder, thereby enabling the beads to function as microlenses. The invention also provides a camera combination and imaging method. Embodiments of the invention provide improved sensitivity and latitude in scene exposure range.
    Type: Grant
    Filed: June 12, 2002
    Date of Patent: November 18, 2003
    Assignee: Eastman Kodak Company
    Inventors: Krishnan Chari, Richard P. Szajewski, Lyn M. Irving
  • Publication number: 20030175719
    Abstract: A method of identifying nucleic acid samples comprising: providing a mircoarray including a substrate coated with a composition including a population of nucleic acid probe modified micro-spheres immobilized in a coating containing a gelling agent or a precursor to a gelling agent, wherein a first portion of the micro-spheres is submerged in the gelatin coating and a second portion is exposed above the gelatin coating and is substantially free of gelatin, at least one sub-population of the population micro-spheres containing an optical barcode generated from at least one colorant associated with the micro-spheres and including a nucleic acid probe sequence; contacting the array with a target nucleic acid sequence; and detecting the color barcode of the sub-population of micro-spheres due to the interaction of the probe nucleic acid sequence and the fluorescently/chemiluminescently labeled nucleic acid sample target nucleic acid sequence.
    Type: Application
    Filed: March 15, 2002
    Publication date: September 18, 2003
    Inventors: Tiecheng A. Qiao, Krishnan Chari, Douglas L. Vizard
  • Publication number: 20030170392
    Abstract: A method of making a microarray comprising the steps of:
    Type: Application
    Filed: March 7, 2002
    Publication date: September 11, 2003
    Applicant: Eastman Kodak Company
    Inventors: Krishnan Chari, Tiecheng A. Qiao, Ramasubramaniam Hanumanthu
  • Patent number: 6607873
    Abstract: Disclosed is a color film comprising (1) a support layer, (2) a light sensitive layer, and (3) a water permeable color filter array (CFA) layer comprising a continuous phase transparent binder containing a random distribution of colored transparent beads, said beads comprising a water-immiscible synthetic polymer or copolymer.
    Type: Grant
    Filed: August 3, 2001
    Date of Patent: August 19, 2003
    Assignee: Eastman Kodak Company
    Inventors: Krishnan Chari, Sidney J. Bertucci, Michael J. Simons
  • Patent number: 6602656
    Abstract: Disclosed is an imaging element comprising a single layer containing a random distribution of a colored bead population of one or more colors coated above one or more layers comprising light sensitive silver halide emulsion grains, wherein the population comprises beads of at least one color in which at least 25% (based on projected area) of the beads of that color have an ECD less than 2 times the ECD of the silver halide grains in said one emulsion layer or in the fastest emulsion layer in the case of more than one emulsion layer
    Type: Grant
    Filed: August 22, 2002
    Date of Patent: August 5, 2003
    Assignee: Eastman Kodak Company
    Inventors: Joel D. Shore, Krishnan Chari, Dennis R. Perchak
  • Publication number: 20030143542
    Abstract: A method of identifying nucleic acid samples comprising:
    Type: Application
    Filed: December 21, 2001
    Publication date: July 31, 2003
    Inventors: Tiecheng A. Qiao, Krishnan Chari, Douglas L. Vizard
  • Patent number: 6599668
    Abstract: Disclosed is process for forming a color filter array layer on a transparent surface, comprising the step of applying a water-borne solid-particle dispersion of randomly disposed colored beads of a water-immiscible synthetic polymer to the surface.
    Type: Grant
    Filed: August 3, 2001
    Date of Patent: July 29, 2003
    Assignee: Eastman Kodak Company
    Inventors: Krishnan Chari, John C. Kowalczyk
  • Publication number: 20030138649
    Abstract: A gelatin-based substrate for fabricating protein arrays, the substrate containing: gelatin and a trifunctional compound A-L-B; wherein A is a functional group capable of interacting with the gelatin; L is a linking group capable of interacting with A and with B; and B is a functional group capable of interacting with a protein capture agent. A may be the same or different from B.
    Type: Application
    Filed: November 30, 2001
    Publication date: July 24, 2003
    Inventors: Tiecheng A. Qiao, Krishnan Chari, Thomas L. Penner, Zhihao Yang
  • Publication number: 20030064301
    Abstract: Disclosed is process for forming a color filter array layer on a transparent surface, comprising the step of applying a water-borne solid-particle dispersion of randomly disposed colored beads of a water-immiscible synthetic polymer to the surface.
    Type: Application
    Filed: August 3, 2001
    Publication date: April 3, 2003
    Applicant: Eastman Kodak Company
    Inventors: Krishnan Chari, John C. Kowalczyk
  • Publication number: 20030054264
    Abstract: Disclosed is a color film comprising (1) a support layer, (2) a light sensitive layer, and (3) a water permeable color filter array (CFA) layer comprising a continuous phase transparent binder containing a random distribution of colored transparent beads, said beads comprising a water-immiscible synthetic polymer or copolymer.
    Type: Application
    Filed: August 3, 2001
    Publication date: March 20, 2003
    Applicant: Eastman Kodak Company
    Inventors: Krishnan Chari, Sidney J. Bertucci, Michael J. Simons
  • Patent number: 6203970
    Abstract: A photosensitive photographic element is described which comprises a support having at least one ? hydrophilic silver halide containing layer. On the hydrophilic silver halide containing layers there is an overcoat layer. The overcoat layer comprises a hydrophobic thermoplastic polymer that is present in the form of a porous membrane. The pores of the membrane are occupied by a hydrophilic composition.
    Type: Grant
    Filed: December 16, 1999
    Date of Patent: March 20, 2001
    Assignee: Eastman Kodak Company
    Inventor: Krishnan Chari