Patents by Inventor Kristian Solem
Kristian Solem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9289545Abstract: A control system (23) is arranged to control the operation of an apparatus (200) for extracorporeal blood treatment. The apparatus (200) comprises an extracorporeal blood circuit (20) and a connection system (C) for connecting the blood circuit (20) to the vascular system of a patient. The blood circuit (20) comprises a blood processing device (6), and at least one pumping device (3). The control system is operable to switch between a pre-treatment mode and a blood treatment mode. The blood treatment mode involves operating the blood circuit (20) to pump blood from the vascular system via the connection system (C) through the blood processing device (6) and back to the vascular system via the connection system (C). The control system (23) is operable to obtain measurement data from at least one energy transfer sensor (40) arranged to sense a transfer of energy between the patient and the connection system (C) or between the patient and the blood circuit (20).Type: GrantFiled: December 22, 2010Date of Patent: March 22, 2016Assignee: Gambro Lundia ABInventors: Bo Olde, Kristian Solem, Thomas Hertz, Jan Sternby, Anders Wieslander
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Patent number: 9289544Abstract: A device is arranged to detect a configuration of withdrawal and return devices (1, 14, 111, 112, 211, 212, 702, 703, 802, 803) coupling an extracorporeal blood flow circuit (20) to a cardiovascular system of a subject. The device comprises a signal processor (29), which is configured to receive a primary measurement signal obtained by a primary pressure sensor (4a, 4b, 4c) in the extracorporeal blood flow circuit (20). The device is further configured to process the primary measurement signal for extraction of primary pressure data originating from a subject pulse generator (3?) in the cardiovascular system or extracorporeal blood flow circuit (20), the primary pressure data comprising at least a part of a first pulse from the subject pulse generator (3?). The device is also configured to calculate a parameter value from the primary pressure data and to determine the configuration based at least partly on the parameter value.Type: GrantFiled: December 22, 2010Date of Patent: March 22, 2016Assignee: Gambro Lundia ABInventors: Bo Olde, Kristian Solem
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Publication number: 20150306293Abstract: A monitoring device (7) operates on a pressure signal from a blood processing apparatus, e.g. a dialysis machine, which has an extracorporeal blood circuit connected to a vascular system of a subject for pumping blood through a dialyzer, and a treatment fluid supply system for pumping a treatment fluid through the dialyzer. The monitoring device (7) has a first input block (50) for obtaining a first pressure signal (y) from a first pressure sensor (6a) in the extracorporeal blood circuit, and a second input block (51) for obtaining a second pressure signal (w) from a second pressure sensor (6b) in the treatment fluid supply system.Type: ApplicationFiled: December 11, 2013Publication date: October 29, 2015Inventors: Jan Sternby, Mattias Holmer, Bo Olde, Kristian Solem, Anders Wallenborg, Per Hansson
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Publication number: 20150019170Abstract: A monitoring device is arranged to receive a time-dependent measurement signal from a pressure sensor in a fluid containing system, which is associated with a first pulse generator and a second pulse generator. The pressure sensor is arranged in the fluid containing system to detect a first pulse originating from the first pulse generator and a second pulse originating from the second pulse generator. The monitoring device is configured to process the measurement signal to remove the first pulse. In this process, the monitoring device receives the measurement signal, obtains a first pulse profile which is a predicted temporal signal profile of the first pulse, and filters the measurement signal in the time-domain, using the first pulse profile, to essentially eliminate the first pulse while retaining the second pulse. The fluid containing system may include an extracorporeal blood flow circuit and a blood circuit of a human patient.Type: ApplicationFiled: May 5, 2014Publication date: January 15, 2015Applicant: Gambro Lundia ABInventors: Kristian Solem, Bo Olde
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Publication number: 20140298891Abstract: A device monitors a blood path from a blood vessel access of a human subject through an extracorporeal blood processing apparatus and back to the blood vessel access. A pumping device in the blood path is operable to pump blood through the blood path from the blood withdrawal device to the blood return device. The monitoring device obtains pressure data from a pressure sensor arranged upstream of the pumping device in the blood path, and processes the pressure data for detection of a disruption of the blood path downstream of the pumping device, e.g. caused by VND (Venous Needle Dislodgement).Type: ApplicationFiled: May 23, 2012Publication date: October 9, 2014Applicant: Gambro Lundia ABInventors: Mattias Holmer, Bo Olde, Kristian Solem
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Patent number: 8831717Abstract: The invention relates to estimation of a patient's propensity to suffer from symptomatic hypotension during extracorporeal blood treatment. An electromagnetic test signal, which is applied over a thoracic region of the patient via at least one transmitter electrode. A result signal produced in response to the test signal is received via at least one receiver electrode on the patient. A test parameter is derived based on the result signal. The test parameter expresses a fluid status of the thoracic region of the patient, and it is determined whether the test parameter fulfills an alarm criterion. If the test parameter fulfills an alarm criteria, an alarm signal is generated. This signal indicates that the patient is hypotension prone, and that appropriate measures should be taken.Type: GrantFiled: September 6, 2007Date of Patent: September 9, 2014Assignee: Gambro Lundia ABInventors: Kristian Solem, Bo Olde
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Publication number: 20140231319Abstract: A device removes first pulses in a pressure signal of a pressure sensor which is arranged in a fluid containing system to detect the first pulses, which originate from a first pulse generator, and second pulses, which originate from a second pulse generator. The first pulse generator operates in a sequence of pulse cycles, each pulse cycle resulting in at least one first pulse. The device repetitively obtains a current data sample, calculates a corresponding reference value and subtracts the reference value from the current data sample. The reference value is calculated as a function of other data sample(s) in the same pressure signal. The fluid containing system may include an extracorporeal blood flow circuit, e.g. as part of a dialysis machine, and a cardiovascular system of a human patient.Type: ApplicationFiled: June 20, 2012Publication date: August 21, 2014Applicant: GAMBRO LUNDIA ABInventors: Bo Olde, Kristian Solem, Mattias Holmer, Jan Sternby
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Patent number: 8805487Abstract: A cardiac-activity based prediction of a rapid drop in a patient's blood pressure during extracorporeal blood treatment is disclosed. A proposed alarm apparatus includes a primary beat morphology analysis unit bank of secondary analysis units and an alarm generating unit. The primary beat morphology analysis unit discriminates heart beats in a received basic electrocardiogram signal, classifies each beat into one out of at least two different beat categories, and associates each segment of the signal with relevant event-type data. The event-type data and the basic electrocardiogram signal together form an enhanced electrocardiogram signal, based upon which the primary beat morphology analysis unit determines whether one or more secondary signal analyses should be performed.Type: GrantFiled: October 5, 2012Date of Patent: August 12, 2014Assignee: Gambro Lundia ABInventors: Leif Sömmo, Kristian Solem
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Patent number: 8715216Abstract: A monitoring device is arranged to receive a time-dependent measurement signal from a pressure sensor in a fluid containing system, which is associated with a first pulse generator and a second pulse generator. The pressure sensor is arranged in the fluid containing system to detect a first pulse originating from the first pulse generator and a second pulse originating from the second pulse generator. The monitoring device is configured to process the measurement signal to remove the first pulse. In this process, the monitoring device receives the measurement signal, obtains a first pulse profile which is a predicted temporal signal profile of the first pulse, and filters the measurement signal in the time-domain, using the first pulse profile, to essentially eliminate the first pulse while retaining the second pulse. The fluid containing system may include an extracorporeal blood flow circuit and a blood circuit of a human patient.Type: GrantFiled: June 26, 2009Date of Patent: May 6, 2014Assignee: Gambro Lundia ABInventors: Bo Olde, Kristian Solem
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Patent number: 8718957Abstract: A device is provided for monitoring the integrity of a flow circuit in fluid communication with a receptacle. The flow circuit includes a pumping device for transferring fluid through the flow circuit. The device operates according to a monitoring method in which a pressure signal is received from a pressure sensor, the pressure signal being indicative of fluid pressure in the receptacle or the flow circuit. The pressure signal is then processed for detection of a beating signal. The beating signal manifests itself as an amplitude modulation of the pressure signal and is formed by interference between pressure waves generated by a pulse generator associated with the receptacle and pressure waves generated by the pumping device. The integrity of the flow circuit is determined based at least partly on the presence or absence of the beating signal. The device and the flow circuit may be part of an apparatus for extracorporeal blood treatment, and the method may be implemented as a computer program product.Type: GrantFiled: April 16, 2009Date of Patent: May 6, 2014Assignee: Gambro Lundia ABInventors: Martin Furmanski, Anders Roslund, Bo Olde, Kristian Solem
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Publication number: 20130274570Abstract: A monitoring arrangement 100 is configured to predict a rapid syruptomatic drop in a subject's blood pressure, e.g. during a medical treatment or when operating aircraft. To this aim, a pulse shape parameter (pps) with respect to a peripheral body part (105) of the subject (P) is repeatedly registered by means of a pulse oximetry instrument (110) adapted to detect light response variations in blood vessels. A respective pulse magnitude measure is calculated based on each of a number of received pulse shape parameters (pps), and a statistical dispersion measure is calculated based on the thus-calculated pulse magnitude measure. It is investigated whether or not the statistical dispersion measure fulfils a decision criterion relative to a reference measure. An output signal (?) is generated if the decision criterion is found to be fulfilled.Type: ApplicationFiled: December 22, 2010Publication date: October 17, 2013Applicant: GAMBRO LUNDIA ABInventors: Bo Olde, Kristian Solem
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Publication number: 20130204174Abstract: A device is configured to detect a fault condition in a fluid connection system between a first (e.g. extracorporeal blood circuit) and second (e.g. vascular system of a patient) fluid containing systems. The first and second fluid containing systems comprise a first and second pulse generator, respectively. A pressure sensor is arranged in the first fluid containing system to detect pulses originating from the first and second pulse generator. The device operates according to a detection method, by generating a time-dependent monitoring signal based on measurement data obtained from said at least one pressure sensor, such that the monitoring signal at least comprises one or more first pulses; processing (42) the monitoring signal to calculate a parameter value which is indicative of the shape of at least part of a first pulse in the monitoring signal, and evaluating (44) the parameter value for detection of the fault condition.Type: ApplicationFiled: December 22, 2010Publication date: August 8, 2013Inventors: Bo Olde, Kristian Solem
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Publication number: 20130204542Abstract: A device is configured to monitor the integrity of a connection system between first and second fluid containing systems comprising first and second pulse generators. A pressure sensor is arranged in the first fluid containing system to detect first pulses originating from the first pulse generator and second pulses originating from the second pulse generator. The device operates a monitoring method, by generating (42) a time-dependent pressure signal based on measurement data obtained from the pressure sensor such that the pressure signal contains a sequence of apparent pulses. The apparent pulses represent a superposition of the second pulses on the first pulses when the connection system (C) is intact. The device processes (44) the pressure signal to calculate a parameter value based on a pulse feature of at least one of the apparent pulses in the pressure signal.Type: ApplicationFiled: December 22, 2010Publication date: August 8, 2013Applicant: GAMBRO LUNDIA ABInventors: Bo Olde, Kristian Solem
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Publication number: 20130172803Abstract: A control system (23) is arranged to control the operation of an apparatus (200) for extracorporeal blood treatment. The apparatus (200) comprises an extracorporeal blood circuit (20) and a connection system (C) for connecting the blood circuit (20) to the vascular system of a patient. The blood circuit (20) comprises a blood processing device (6), and at least one pumping device (3). The control system is operable to switch between a pre-treatment mode and a blood treatment mode. The blood treatment mode involves operating the blood circuit (20) to pump blood from the vascular system via the connection system (C) through the blood processing device (6) and back to the vascular system via the connection system (C). The control system (23) is operable to obtain measurement data from at least one energy transfer sensor (40) arranged to sense a transfer of energy between the patient and the connection system (C) or between the patient and the blood circuit (20).Type: ApplicationFiled: December 22, 2010Publication date: July 4, 2013Applicant: Gambro Lundia ABInventors: Bo Olde, Kristian Solem, Thomas Hertz, Jan Sternby, Anders Wieslander
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Publication number: 20130150766Abstract: A device is arranged to detect a configuration of withdrawal and return devices (1, 14, 111, 112, 211, 212, 702, 703, 802, 803) coupling an extracorporeal blood flow circuit (20) to a cardiovascular system of a subject. The device comprises a signal processor (29), which is configured to receive a primary measurement signal obtained by a primary pressure sensor (4a, 4b, 4c) in the extracorporeal blood flow circuit (20). The device is further configured to process the primary measurement signal for extraction of primary pressure data originating from a subject pulse generator (3?) in the cardiovascular system or extracorporeal blood flow circuit (20), the primary pressure data comprising at least a part of a first pulse from the subject pulse generator (3?). The device is also configured to calculate a parameter value from the primary pressure data and to determine the configuration based at least partly on the parameter value.Type: ApplicationFiled: December 22, 2010Publication date: June 13, 2013Applicant: GAMBRO LUNDIA ABInventors: Bo Olde, Kristian Solem
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Publication number: 20130096402Abstract: A monitoring arrangement 100 is configured to predict a rapid syruptomatic drop in a subject's blood pressure, e.g. during a medical treatment or when operating aircraft. To this aim, a pulse shape parameter (pps) with respect to a peripheral body part (105) of the subject (P) is repeatedly registered by means of a pulse oximetry instrument (110) adapted to detect light response variations in blood vessels. A respective pulse magnitude measure is calculated based on each of a number of received pulse shape parameters (pps), and a statistical dispersion measure is calculated based on the thus-calculated pulse magnitude measure. It is investigated whether or not the statistical dispersion measure fulfils a decision criterion relative to a reference measure. An output signal (?) is generated if the decision criterion is found to be fulfilled.Type: ApplicationFiled: December 22, 2010Publication date: April 18, 2013Applicant: GAMBRO LUNDIA ABInventors: Bo Olde, Kristian Solem
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Publication number: 20130023776Abstract: A device is configured to monitor a cardiovascular property of a subject. The device obtains measurement data from a primary pressure wave sensor arranged to detect pressure waves in an extracorporeal fluid circuit in fluid communication with the cardiovascular system of the subject. The device has a signal processor configured to generate a time-dependent monitoring signal based on the measurement data, such that the monitoring signal comprises a sequence of heart pulses, wherein each heart pulse represents a pressure wave originating from a heart beat in the subject; determine beat classification data for each heart pulse in the monitoring signal; and calculate, based at least partly on the beat classification data, a parameter value indicative of the cardiovascular property. The beat classification data may distinguish between heart pulses originating from normal heart beats and heart pulses originating from ectopic heart beats.Type: ApplicationFiled: December 22, 2010Publication date: January 24, 2013Applicant: Gambro Lundia ABInventors: Bo Olde, Kristian Solem
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Publication number: 20130006130Abstract: A device in an apparatus for extracorporeal blood treatment is configured to monitor a fluid flow rate (Q) of a cardiovascular system of a subject. The apparatus comprises an extracorporeal blood circuit and a connection (C) for connecting the extracorporeal blood circuit to the cardiovascular system. The device comprises an input for obtaining a time-dependent measurement signal (d(n)) from a pressure sensor in the extracorporeal blood circuit. The pressure sensor is arranged to detect a subject pulse originating from a subject pulse generator in the cardiovascular system of the subject, wherein the system further comprises a signal processor connected to the input. The signal processor is configured to process the measurement signal to obtain a pulse profile (e(n)) which is a temporal signal profile of the subject pulse, and to calculate a fluid flow rate (Q) based at least partly on the temporal signal profile.Type: ApplicationFiled: December 22, 2010Publication date: January 3, 2013Applicant: Gambro Lundia ABInventors: Bo Olde, Kristian Solem
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Publication number: 20130006128Abstract: A monitoring device is included in a medical system to implement a method for prediction of a rapid symptomatic drop in a subject's blood pressure, e.g. during a medical treatment such as dialysis. To this aim, a pulse shape parameter (pPS) with respect to a pulse generator of the subject is registered by means of a pressure sensor arranged in an extracorporeal blood flow circuit coupled to a cardiovascular system of the subject (P). The pressure sensor is configured to detect pressure variations in blood vessels of the subject (P). It is investigated, during measurement period, whether or not one or more of the pulse shape parameters fulfil a decision criterion. An output signal (a) is generated if the decision criterion is found to be fulfilled, to indicate a predicted rapid symptomatic blood pressure decrease in the subject (P).Type: ApplicationFiled: December 22, 2010Publication date: January 3, 2013Applicant: GAMBRO LUNDIA ABInventors: Bo Olde, Kristian Solem
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Patent number: 8311619Abstract: A cardiac-activity based prediction of a rapid drop in a patient's blood pressure during extracorporeal blood treatment is disclosed. A proposed alarm apparatus includes a primary beat morphology analysis unit bank of secondary analysis units and an alarm generating unit. The primary beat morphology analysis unit discriminates heart beats in a received basic electrocardiogram signal, classifies each beat into one out of at least two different beat categories, and associates each segment of the signal with relevant event-type data. The event-type data and the basic electrocardiogram signal together form an enhanced electrocardiogram signal, based upon which the primary beat morphology analysis unit determines whether one or more secondary signal analyses should be performed.Type: GrantFiled: August 10, 2006Date of Patent: November 13, 2012Assignee: Gambro Lundia ABInventors: Leif Sörnmo, Kristian Solem