Patents by Inventor Kunio Kobayashi
Kunio Kobayashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240417379Abstract: A diazepine derivative represented by formula (I), where R1 and R2 represent hydrogen, or R1 and R2 bind together to form a naphthalene ring and the like together with the benzene ring to which they bind, R3, R4, R5, R6, and R7 each represents hydrogen, X represents C, CH or N, Y represents N, NH or C(?O), provided that when X is N, Y is not N or NH, and when X is C or CH, Y is not C(?O), Z represents oxygen or sulfur, A represents benzene ring and the like, B represents NHC(?O) and the like, D and E each represents an atomic bond, G represents benzene which may be substituted, and m represents an integer of 0 to 5) or a pharmacologically acceptable salt thereof, and a P2X4 receptor antagonist.Type: ApplicationFiled: August 28, 2024Publication date: December 19, 2024Applicant: NIPPON CHEMIPHAR CO., LTDInventors: Masatoshi USHIODA, Kunio KOBAYASHI, Daisuke SAITO, Shogo SAKUMA, Toshiyasu IMAI, Kazuhide INOUE
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Patent number: 12116351Abstract: The present invention relates to a diazepine derivative represented by the following general formula (I) (in the formula, R1 and R2 represent hydrogen atom and the like, or R1 and R2 bind together to form a naphthalene ring and the like together with the benzene ring to which they bind, R3 and R4 represent hydrogen atom and the like, R5 represents hydrogen atom and the like, R6 and R7 represent hydrogen atom and the like, X represents C, CH or N, Y represents N, NH or C(?O), provided that when X is N, Y is not N or NH, and when X is C or CH, Y is not C(?O), Z represents oxygen atom or sulfur atom, A represents benzene ring and the like, B represents NHC(?O) and the like, D represents an atomic bond and the like, E represents an atomic bond and the like, G represents benzene which may be substituted and the like, and m represents an integer of 0 to 5) or a pharmacologically acceptable salt thereof, and a P2X4 receptor antagonist.Type: GrantFiled: July 22, 2022Date of Patent: October 15, 2024Assignee: NIPPON CHEMIPHAR CO., LTDInventors: Masatoshi Ushioda, Kunio Kobayashi, Daisuke Saito, Shogo Sakuma, Toshiyasu Imai, Kazuhide Inoue
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Publication number: 20240111097Abstract: A spot size converter includes a first optical waveguide, and a second optical waveguide. The first optical waveguide has a first tapered portion. The first tapered portion extends in a direction in which the first optical waveguide extends, and is thicker with decreasing distance from an end portion of the first optical waveguide and is thinner with decreasing distance from the second optical waveguide. The second optical waveguide is separated from the first tapered portion and has a second tapered portion. The second tapered portion extends in a direction in which the second optical waveguide extends, and is thinner with decreasing distance from the first tapered portion and is thicker with increasing distance from the first tapered portion.Type: ApplicationFiled: September 6, 2023Publication date: April 4, 2024Applicant: Sumitomo Electric Industries, Ltd.Inventors: Kunio KOBAYASHI, Yasutaka MIZUNO
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Publication number: 20230014848Abstract: A semiconductor device includes first semiconductor chips that each include a first control electrode and a first output electrode, second semiconductor chips each include a second control electrode and a second output electrode, first and second input circuit patterns on which the first and second input electrodes are disposed, respectively, first and second control circuit patterns electrically connected to the first and second control electrodes, respectively, first and second resistive elements, and a first inter-board wiring member. The first control electrodes and first resistive element are electrically connected via the first control circuit pattern, the second control electrodes and second resistive element are electrically connected via the second control circuit pattern, and at least one of the first output electrodes and at least one of the second output electrodes are electrically connected to each other via the first inter-board wiring member.Type: ApplicationFiled: May 31, 2022Publication date: January 19, 2023Applicant: FUJI ELECTRIC CO., LTD.Inventors: Rikihiro MARUYAMA, Norihiro KOMIYAMA, Kunio KOBAYASHI, Yuto KOBAYASHI, Takahito HARADA, Hirohisa OYAMA, Masahiro SASAKI, Ryousuke USUI
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Publication number: 20220380322Abstract: The present invention relates to a diazepine derivative represented by the following general formula (I) (in the formula, R1 and R2 represent hydrogen atom and the like, or R1 and R2 bind together to form a naphthalene ring and the like together with the benzene ring to which they bind, R3 and R4 represent hydrogen atom and the like, R5 represents hydrogen atom and the like, R6 and R7 represent hydrogen atom and the like, X represents C, CH or N, Y represents N, NH or C(?O), provided that when X is N, Y is not N or NH, and when X is C or CH, Y is not C(?O), Z represents oxygen atom or sulfur atom, A represents benzene ring and the like, B represents NHC(?O) and the like, D represents an atomic bond and the like, E represents an atomic bond and the like, G represents benzene which may be substituted and the like, and m represents an integer of 0 to 5) or a pharmacologically acceptable salt thereof, and a P2X4 receptor antagonist.Type: ApplicationFiled: July 22, 2022Publication date: December 1, 2022Applicant: NIPPON CHEMIPHAR CO., LTDInventors: Masatoshi USHIODA, Kunio KOBAYASHI, Daisuke SAITO, Shogo SAKUMA, Toshiyasu IMAI, Kazuhide INOUE
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Patent number: 11434207Abstract: The present invention relates to a diazepine derivative represented by the following general formula (I) (in the formula, R1 and R2 represent hydrogen atom and the like, or R1 and R2 bind together to form a naphthalene ring and the like together with the benzene ring to which they bind, R3 and R4 represent hydrogen atom and the like, R5 represents hydrogen atom and the like, R6 and R7 represent hydrogen atom and the like, X represents C, CH or N, Y represents N, NH or C(?O), provided that when X is N, Y is not N or NH, and when X is C or CH, Y is not C(?O), Z represents oxygen atom or sulfur atom, A represents benzene ring and the like, B represents NHC(?O) and the like, D represents an atomic bond and the like, E represents an atomic bond and the like, G represents benzene which may be substituted and the like, and m represents an integer of 0 to 5) or a pharmacologically acceptable salt thereof, and a P2X4 receptor antagonist.Type: GrantFiled: March 23, 2020Date of Patent: September 6, 2022Assignee: NIPPON CHEMIPHAR CO., LTDInventors: Masatoshi Ushioda, Kunio Kobayashi, Daisuke Saito, Shogo Sakuma, Toshiyasu Imai, Kazuhide Inoue
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Patent number: 11121240Abstract: In a semiconductor device using, as a FWD, a diode formed in a silicon carbide (SiC) substrate, while preventing gate oscillation, an increase of switching loss is suppressed at the time of a temperature increase also. A semiconductor device includes: a transistor element; a diode element formed in a SiC substrate; and a resistive element that is electrically connected to a gate of the transistor element, and has a resistor temperature coefficient which is within the range of ±150×10?6/K. The resistive element has a resistor formed of a ceramic-containing material.Type: GrantFiled: February 26, 2019Date of Patent: September 14, 2021Assignee: FUJI ELECTRIC CO., LTD.Inventor: Kunio Kobayashi
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Publication number: 20200223806Abstract: The present invention relates to a diazepine derivative represented by the following general formula (I) (in the formula, R1 and R2 represent hydrogen atom and the like, or R1 and R2 bind together to form a naphthalene ring and the like together with the benzene ring to which they bind, R3 and R4 represent hydrogen atom and the like, R5 represents hydrogen atom and the like, R6 and R7 represent hydrogen atom and the like, X represents C, CH or N, Y represents N, NH or C(?O), provided that when X is N, Y is not N or NH, and when X is C or CH, Y is not C(?O), Z represents oxygen atom or sulfur atom, A represents benzene ring and the like, B represents NHC(?O) and the like, D represents an atomic bond and the like, E represents an atomic bond and the like, G represents benzene which may be substituted and the like, and m represents an integer of 0 to 5) or a pharmacologically acceptable salt thereof, and a P2X4 receptor antagonist.Type: ApplicationFiled: March 23, 2020Publication date: July 16, 2020Applicant: NIPPON CHEMIPHAR CO., LTDInventors: Masatoshi USHIODA, Kunio KOBAYASHI, Daisuke SAITO, Shogo SAKUMA, Toshiyasu IMAI, Kazuhide INOUE
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Patent number: 10633349Abstract: The present invention relates to a diazepine derivative represented by the following general formula (I) (in the formula, R1 and R2 represent hydrogen atom and the like, or R1 and R2 bind together to form a naphthalene ring and the like together with the benzene ring to which they bind, R3 and R4 represent hydrogen atom and the like, R5 represents hydrogen atom and the like, R6 and R7 represent hydrogen atom and the like, X represents C, CH or N, Y represents N, NH or C(?O), provided that when X is N, Y is not N or NH, and when X is C or CH, Y is not C(?O), Z represents oxygen atom or sulfur atom, A represents benzene ring and the like, B represents NHC(?O) and the like, D represents an atomic bond and the like, E represents an atomic bond and the like, G represents benzene which may be substituted and the like, and m represents an integer of 0 to 5) or a pharmacologically acceptable salt thereof, and a P2X4 receptor antagonist.Type: GrantFiled: March 16, 2018Date of Patent: April 28, 2020Assignee: NIPPON CHEMIPHAR CO., LTDInventors: Masatoshi Ushioda, Kunio Kobayashi, Daisuke Saito, Shogo Sakuma, Toshiyasu Imai, Kazuhide Inoue
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Patent number: 10472333Abstract: Compounds represented by the following general formula (I), which has a P2X4 receptor antagonistic activity (in the formula, R1, R2 and R3 represent hydrogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, a halogen atom, and the like, X represents C or N, Y represents N or C(?O), provided that when X is C, Y represents N, and when X is N, Y represents C(?O), the double line consisting of the solid line and the broken line represents a single bond or double bond, n represents an integer of 0 to 6, Z represents O, S, or an atomic bond, and A represents benzene ring, pyridine ring, and the like).Type: GrantFiled: July 19, 2018Date of Patent: November 12, 2019Assignees: NIPPON CHEMIPHAR CO., LTD., KYUSHU UNIVERSITYInventors: Shogo Sakuma, Kunio Kobayashi, Masatoshi Ushioda, Toshiyasu Imai, Kazuhide Inoue
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Publication number: 20190326423Abstract: In a semiconductor device using, as a FWD, a diode formed in a silicon carbide (SiC) substrate, while preventing gate oscillation, an increase of switching loss is suppressed at the time of a temperature increase also. A semiconductor device includes: a transistor element; a diode element formed in a SiC substrate; and a resistive element that is electrically connected to a gate of the transistor element, and has a resistor temperature coefficient which is within the range of ±150×10?6/K. The resistive element has a resistor formed of a ceramic-containing material.Type: ApplicationFiled: February 26, 2019Publication date: October 24, 2019Inventor: Kunio KOBAYASHI
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Patent number: 10173990Abstract: Provided are a compound represented by the following Formula (III), a tautomer or stereoisomer of the compound, or a pharmaceutically acceptable salt or solvate thereof used as a therapeutic agent for gout or hyperuricemia.Type: GrantFiled: December 28, 2015Date of Patent: January 8, 2019Assignees: Nippon Chemiphar Co., Ltd., J-Pharma Co., Ltd., DeThree Res. Lab. Inc.Inventors: Tsuyoshi Endo, Kunio Kobayashi, Hiroto Tanaka, Daisuke Saito, Masuharu Hirano, Hitoshi Endou, Naohiko Anzai
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Patent number: 10150744Abstract: The present invention relates to a compound represented by the following general formula (I), which has a P2X4 receptor antagonistic activity (in the formula, R1, R2 and R3 represent hydrogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, a halogen atom, and the like, X represents C or N, Y represents N or C(?O), provided that when X is C, Y represents N, and when X is N, Y represents C(?O), the double line consisting of the solid line and the broken line represents a single bond or double bond, n represents an integer of 0 to 6, Z represents O, S, or an atomic bond, and A represents benzene ring, pyridine ring, and the like).Type: GrantFiled: July 11, 2014Date of Patent: December 11, 2018Assignees: NIPPON CHEMIPHAR CO., LTD, KYUSHU UNIVERSITYInventors: Shogo Sakuma, Kunio Kobayashi, Masatoshi Ushioda, Toshiyasu Imai, Kazuhide Inoue
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Publication number: 20180319752Abstract: Compounds represented by the following general formula (I), which has a P2X4 receptor antagonistic activity (in the formula, R1, R2 and R3 represent hydrogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, a halogen atom, and the like, X represents C or N, Y represents N or C(?O), provided that when X is C, Y represents N, and when X is N, Y represents C(?O), the double line consisting of the solid line and the broken line represents a single bond or double bond, n represents an integer of 0 to 6, Z represents O, S, or an atomic bond, and A represents benzene ring, pyridine ring, and the like).Type: ApplicationFiled: July 19, 2018Publication date: November 8, 2018Applicants: NIPPON CHEMIPHAR CO., LTD., KYUSHU UNIVERSITYInventors: Shogo SAKUMA, Kunio KOBAYASHI, Masatoshi USHIODA, Toshiyasu IMAI, Kazuhide INOUE
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Publication number: 20180201587Abstract: The present invention relates to a diazepine derivative represented by the following general formula (I) (in the formula, R1 and R2 represent hydrogen atom and the like, or R1 and R2 bind together to form a naphthalene ring and the like together with the benzene ring to which they bind, R3 and R4 represent hydrogen atom and the like, R5 represents hydrogen atom and the like, R6 and R7 represent hydrogen atom and the like, X represents C, CH or N, Y represents N, NH or C(?O), provided that when X is N, Y is not N or NH, and when X is C or CH, Y is not C(?O), Z represents oxygen atom or sulfur atom, A represents benzene ring and the like, B represents NHC(?O) and the like, D represents an atomic bond and the like, E represents an atomic bond and the like, G represents benzene which may be substituted and the like, and m represents an integer of 0 to 5) or a pharmacologically acceptable salt thereof, and a P2X4 receptor antagonist.Type: ApplicationFiled: March 16, 2018Publication date: July 19, 2018Applicant: NIPPON CHEMIPHAR CO., LTDInventors: Masatoshi USHIODA, Kunio KOBAYASHI, Daisuke SAITO, Shogo SAKUMA, Toshiyasu IMAI, Kazuhide INOUE
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Patent number: 9969700Abstract: The present invention relates to a diazepine derivative represented by the following general formula (I) (in the formula, R1 and R2 represent hydrogen atom and the like, or R1 and R2 bind together to form a naphthalene ring and the like together with the benzene ring to which they bind, R3 and R4 represent hydrogen atom and the like, R5 represents hydrogen atom and the like, R6 and R7 represent hydrogen atom and the like, X represents C, CH or N, Y represents N, NH or C(?O), provided that when X is N, Y is not N or NH, and when X is C or CH, Y is not C(?O), Z represents oxygen atom or sulfur atom, A represents benzene ring and the like, B represents NHC(?O) and the like, D represents an atomic bond and the like, E represents an atomic bond and the like, G represents benzene which may be substituted and the like, and m represents an integer of 0 to 5) or a pharmacologically acceptable salt thereof, and a P2X4 receptor antagonist.Type: GrantFiled: June 8, 2016Date of Patent: May 15, 2018Assignee: NIPPON CHEMIPHAR CO., LTD.Inventors: Masatoshi Ushioda, Kunio Kobayashi, Daisuke Saito, Shogo Sakuma, Toshiyasu Imai, Kazuhide Inoue
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Patent number: 9873683Abstract: The present invention relates to a compound represented by the following general formula (II), wherein, in the formula, R1a to R6a represent hydrogen atom, an alkyl group having 1 to 8 carbon atoms, and the like, Xa represents C or N, Ya represents N or C(?O), provided that when Xa is C, Ya represents N, and when Xa is N, Ya represents C(?O), the double line consisting of the solid line and the broken line represents a single bond or double bond, Aa represents benzene ring, pyridine ring, and the like, Da represents tetrazole ring, imidazole ring, and the like, Ea represents —(CR9aR10a)p-Ta-, and Ga represents benzene ring, pyridine ring, and the like, which has a P2X4 receptor antagonistic activity.Type: GrantFiled: July 11, 2014Date of Patent: January 23, 2018Assignees: NIPPON CHEMIPHAR CO., LTD, KYUSHU UNIVERSITYInventors: Shogo Sakuma, Kunio Kobayashi, Masatoshi Ushioda, Daisuke Saito, Toshiyasu Imai, Kazuhide Inoue
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Patent number: 9840497Abstract: The present invention relates to a compound represented by the following general formula (II), wherein, in the formula, R1a to R6a represent hydrogen atom, an alkyl group having 1 to 8 carbon atoms, and the like, Xa represents C or N, Ya represents N or C(?O), provided that when Xa is C, Ya represents N, and when Xa is N, Ya represents C(?O), the double line consisting of the solid line and the broken line represents a single bond or double bond, Aa represents benzene ring, pyridine ring, and the like, Da represents tetrazole ring, imidazole ring, and the like, Ea represents —(CR9aR10a)p-Ta-, and Ga represents benzene ring, pyridine ring, and the like, which has a P2X4 receptor antagonistic activity.Type: GrantFiled: July 11, 2014Date of Patent: December 12, 2017Assignees: NIPPON CHEMIPHAR CO., LTD, KYUSHU UNIVERSITYInventors: Shogo Sakuma, Kunio Kobayashi, Masatoshi Ushioda, Daisuke Saito, Toshiyasu Imai, Kazuhide Inoue
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Publication number: 20170290795Abstract: Provided are a compound represented by the following Formula (III), a tautomer or stereoisomer of the compound, or a pharmaceutically acceptable salt or solvate thereof used as a therapeutic agent for gout or hyperuricemia.Type: ApplicationFiled: December 28, 2015Publication date: October 12, 2017Applicant: J-Pharma Co., Ltd.Inventors: Tsuyoshi Endo, Kunio Kobayashi, Hiroto Tanaka, Daisuke Saito, Masaharu Hirano, Hitoshi Endou, Naohiko Anzai
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Publication number: 20170081294Abstract: The present invention relates to a compound represented by the following general formula (I), which has a P2X4 receptor antagonistic activity (in the formula, R1, R2 and R3 represent hydrogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, a halogen atom, and the like, X represents C or N, Y represents N or C(?O), provided that when X is C, Y represents N, and when X is N, Y represents C(?O), the double line consisting of the solid line and the broken line represents a single bond or double bond, n represents an integer of 0 to 6, Z represents O, S, or an atomic bond, and A represents benzene ring, pyridine ring, and the like).Type: ApplicationFiled: July 11, 2014Publication date: March 23, 2017Applicants: NIPPON CHEMIPHAR CO., LTD., KYUSHU UNIVERSITYInventors: Shogo SAKUMA, Kunio KOBAYASHI, Masatoshi USHIODA, Toshiyasu IMAI, Kazuhide INOUE