Abstract: An apparatus (100) for metered dispensing of a liquid from a container (3) and a spray applicator having the apparatus (100). The apparatus (100) comprises a base body (5) and a nozzle body (16) having an outlet nozzle. The nozzle body (16) is mounted so as to be displaceable relative to the base body (5) from a dispensing to a clamping position. The apparatus (100) comprises a reset spring (14) for moving the nozzle body (16) from the clamping to the dispensing position. The nozzle body (16) and the valve body form a burst chamber (19). By pressure on the trigger mechanism (26), the locking of the valve body (10) is triggered and the spray burst spring (7) presses the valve body (10) in the nozzle direction. A non-return valve is arranged upstream in the valve body. The spray burst chamber is connected to the outlet nozzle.

Abstract: The invention is a device for the enucleation of intracorporeal tissue regions, in particular of the prostate, with a probe at whose distal end at least one freely accessible electrode body is mounted to which electrical energy can be applied via at least one electrical line running in the longitudinal extent of the probe. The electrode body has a dome-shaped electrode surface and has cross-sectional surfaces which are orientated orthogonally to the longitudinal extent of the probe surface areas along a first axial portion which contains a distal dome end of the electrode body, which increase continuously as the distance from the distal dome end increases.

Abstract: An apparatus (100) for metered dispensing of a liquid from a container (3) and a spray applicator having the apparatus (100). The apparatus (100) comprises a base body (5) and a nozzle body (16) having an outlet nozzle. The nozzle body (16) is mounted so as to be displaceable relative to the base body (5) from a dispensing to a clamping position. The apparatus (100) comprises a reset spring (14) for moving the nozzle body (16) from the clamping to the dispensing position. The nozzle body (16) and the valve body form a burst chamber (19). By pressure on the trigger mechanism (26), the locking of the valve body (10) is triggered and the spray burst spring (7) presses the valve body (10) in the nozzle direction. A non-return valve is arranged upstream in the valve body. The spray burst chamber is connected to the outlet nozzle.

Abstract: A bone graft substitute which combines substantially the high mechanical stability of spherical porous granules without the limitation of reduced intergranular space. The granules have a high porosity whilst maintaining high stability, and can be pushed into a defect without risking significant breakage of the granules and, simultaneously, bone cells can grow into the space between the granules. In an exemplary embodiment of the invention, the surface of the granules comprises indentations, when viewed from the exterior of the granules. An indentation increases the porosity within the implanted mass significantly and thus provides more space between the granules for tissue ingrowth. Due to the indentations on the granules, the granules have an irregular shape and thus an increase in the intergranular space is achieved, while mechanical stability is maintained. A biocompatible polymer, such as a collagen or gelatin, is disposed about at least some of the granules to form a coating thereon.

Abstract: A bone graft substitute which combines substantially the high mechanical stability of spherical porous granules without the limitation of reduced intergranular space, and a method for manufacturing the bone graft substitute. In an exemplary embodiment of the invention, the surface of the granules comprises indentations that increases the porosity within the implanted mass significantly and thus provides more space between the granules for tissue ingrowth. The indentations on the granules cause them to have an irregular shape and thus an increase in the intergranular space is achieved, while mechanical stability is maintained. An exemplary method according to the invention includes the steps of manufacturing the granules; mixing the granules with a porogen; pressing the porogen into the surface of at least a portion of the granules; and removing the porogen from the implant mass to form the indentations in the surface where the porogen was pressed into the granules.

Abstract: A bone graft substitute which combines substantially the high mechanical stability of spherical porous granules without the limitation of reduced intergranular space. The granules have a high porosity whilst maintaining high stability, and can be pushed into a defect without risking significant breakage of the granules and, simultaneously, bone cells can grow into the space between the granules. In an exemplary embodiment of the invention, the surface of the granules comprises indentations, when viewed from the exterior of the granules. An indentation increases the porosity within the implanted mass significantly and thus provides more space between the granules for tissue ingrowth. Due to the indentations on the granules, the granules have an irregular shape and thus an increase in the intergranular space is achieved, while mechanical stability is maintained. A biocompatible polymer, such as a polypeptide, is disposed about at least some of the granules to form a coating thereon.

Abstract: There is described a bone graft substitute which combines substantially the high mechanical stability of spherical porous granules without the limitation of reduced intergranular space. The structure inside the granules has a high porosity whilst maintaining high stability, so that the granules can be pushed into a defect without risking significant breakage of the granules and, at the same time, the bone cells can grow into the space between the granules. In an exemplary embodiment of the invention, the surface of the granules comprises indentations, when viewed from the exterior of the granules. An indentation increases the porosity within the implanted mass significantly and thus provides more space between the granules for tissue ingrowth. Due to the indentations on the granules, the granules have an irregular shape and thus an increase in the intergranular space is achieved, while mechanical stability is maintained.

Abstract: Medical implant which at least partially comprises a biocompatible, electrically conductive polymer with electrical resistivity p, having the property of being able to be heated and softened by a flow of current through the polymer.

Abstract: A medical implant is for insertion into a bone. The medical implant may include a zone having a polymer material configured to transition from a solid condition to a softened condition when exposed to electromagnetic radiation, and be flowable into interspaces of the bone in the softened condition. The medical implant may include a light-conducting portion configured to conduct the electromagnetic radiation from a radiation source to the zone when the medical implant is inserted into the bone.

Abstract: Medical implant which at least partially comprises a biocompatible, electrically conductive polymer with electrical resistivity p, having the property of being able to be heated and softened by a flow of current through the polymer.

Abstract: Medical implant which at least partially comprises a biocompatible, electrically conductive polymer with electrical resistivity p, having the property of being able to be heated and softened by a flow of current through the polymer.

Abstract: A device for the propulsion and eccentric braking of a vehicle having a pedal drive, which includes a first shaft, a drive mechanism including one or a plurality of chain wheels, belt pulleys or elements of a Cardan drive, a second hollow shaft arranged concentrically about the first shaft mounted into a rear wheel, a freewheel clutch mounted between the first shaft and the drive mechanism, and an optionally engageable reverse gear mechanism mounted between the first and the second shaft. The first and the second shafts are connected to each other in a torsionally rigid manner when the reverse gear mechanism is in the engaged and disengaged state. The freewheel clutch prevents a rotation of the drive mechanism relative to the first shaft in a clockwise direction and is in a freewheeling state when the drive mechanism rotates in a counter-clockwise direction relative to the first shaft.

Abstract: Medical implant at least partially consisting of a polymer, where: A) It consists only partially of one or several polymers compatible with the body, which are at least partially containing a colored substance, a reflecting coating or a self-colored; or B) It consists wholly of one or several polymers compatible with the body, whereof only a part contains a colored substance, a reflecting coating or a self-colored; or C) it comprises one or several polymers compatible with the body, which are at least partially coated with a color layer or a reflecting layer, or D) It presents at least a part of a polymer without a coating, which is capable of receiving appropriate colored substances if put in contact with color containing body fluids, so that E) The colored or color containing polymers (A), or those polymer layers that border on the reflecting coatings (A), the color substance receiving coatings (D) or the coatings consisting only of a color layer can be warmed-up and softened by electromagnetic radiation,

Abstract: A vehicle that includes a vehicle frame having a steering device, a first vehicle wheel fastened to the steering device, one or more second vehicle wheels fastened to the vehicle frame, a braking device, and a drive device having a pedal crank that can be driven by pedals. The vehicle further includes a freewheel clutch and an optionally engageable reverse gear mechanism. When the freewheel clutch is in an engaged state in a drive mode during the forward movement of the pedals, force is transmitted from the drive device to at least the second vehicle wheel. The freewheel clutch can be switched from the drive mode into a braking mode when the reverse gear mechanism is in the engaged state so that, in the braking mode, the pedal crank and the at least one second vehicle wheel are connected to each other in a torsionally rigid manner.

Abstract: A medical implant for insertion into bone including a zone sensitive to electromagnetic radiation from a radiation source, the zone comprising a polymer material configured to transition from a solid condition to a softened condition when the zone is exposed to the electromagnetic radiation and being flowable into interspaces of the bone in the softened condition, and a light-conducting portion configured to conduct the electromagnetic radiation from the radiation source to the zone when the medical implant is inserted into the bone.

Abstract: Medical implant at least partially consisting of a polymer, where: A) It consists only partially of one or several polymers compatible with the body, which are at least partially containing a colored substance, a reflecting coating or a self-colored; or B) It consists wholly of one or several polymers compatible with the body, whereof only a part contains a colored substance, a reflecting coating or a self-colored; or C) It comprises one or several polymers compatible with the body, which are at least partially coated with a color layer or a reflecting layer, or D) It presents at least a part of a polymer without a coating, which is capable of receiving appropriate colored substances if put in contact with color containing body fluids, so that E) The colored or color containing polymers (A), or those polymer layers that border on the reflecting coatings (A), the color substance receiving coatings (D) or the coatings consisting only of a color layer can be warmed-up and softened by electromagnetic radiation,

Abstract: Moldable bone implants for use in a bone defect or wound include a plurality of biocompatible granules and a biocompatible polymer that together form an implant mass. The polymer is softened with a plasticizer to make the implant mass moldable. The plasticizer can dissipate or be extracted to cause the implant mass to harden. The implant mass can be shaped in-situ or ex-situ. Implants formed in-situ are shaped by the bone defect or wound. The implant becomes hard through contact with body fluids, which extracts the plasticizer from the implant mass. Bone implants formed ex-situ, such as in a mold, are shaped by a mold, for example, and then hardened by placing the implant mass in contact with a hardening agent, such as water, which extracts the plasticizer from the implant mass. The shaped, hardened implant can be placed into a bone defect of corresponding size and shape.

Abstract: A biocompatible and biodegradable implant for a cavity in a bone of a living organism is made of biocompatible and biodegradable granules. The biocompatible and biodegradable granules are provided with a coating, which includes at least one layer of a biocompatible and biodegradable polymer. The biocompatible and biodegradable implants are obtained by fusing together the polymer-coated granules through polymer-linkage of the polymer coatings of neighboring granules.

Abstract: Medical implant which at least partially comprises a biocompatible, electrically conductive polymer with electrical resistivity p, having the property of being able to be heated and softened by a flow of current through the polymer.

Abstract: There is described a biocompatible implant for the filling of a cavity in a living organism such as, for example, a bone defect or an extraction wound, comprising an open porous scaffold and/or a composite matrix comprising a plurality of inorganic or synthetic granules and a synthetic polymer matrix, and further comprising a biodegradable membrane which is interconnectibly sealed to a surface portion of the scaffold or composite matrix such, that the scaffold or composite matrix and the membrane form a single piece of matter. In one embodiment, the implant is biodegradable.