Patents by Inventor Kyuson Yun

Kyuson Yun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220187281
    Abstract: Described herein are methods and systems for evaluating cell samples, including tissue samples such as cancer tissue. In some cases, evaluating cell samples comprises longitudinal evaluation of one or more candidate molecules. Methods and systems for assessing cellular viability are provided.
    Type: Application
    Filed: March 18, 2020
    Publication date: June 16, 2022
    Inventor: Kyuson YUN
  • Patent number: 11331304
    Abstract: YAP1 inhibitors and methods of treating a subject with a cancer that include administering a YAP1 inhibitor are disclosed. Also disclosed are methods for determining responsiveness to a YAP1 inhibitor in a subject, methods for diagnosing a tumor in a subject including determining the level of YAP1 expression, compositions that include YAP1 inhibitors, and methods of using those compositions.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: May 17, 2022
    Assignee: The Jackson Laboratory
    Inventors: Kyuson Yun, Hai-Xiao Zhai
  • Publication number: 20190298693
    Abstract: YAP1 inhibitors and methods of treating a subject with a cancer that include administering a YAP1 inhibitor are disclosed. Also disclosed are methods for determining responsiveness to a YAP1 inhibitor in a subject, methods for diagnosing a tumor in a subject including determining the level of YAP1 expression, compositions that include YAP1 inhibitors, and methods of using those compositions.
    Type: Application
    Filed: May 11, 2017
    Publication date: October 3, 2019
    Inventors: Kyuson Yun, Hai-Xiao Zhai
  • Publication number: 20090123439
    Abstract: The present invention provides methods for diagnosis and prognosis of cancer stem cells (CSC) using expression analysis of one or more groups of genes, and a combination of expression analysis from a biological sample from the subject. The methods of the invention provide a method for accuracy detecting cancer stem cells in a population of cancer cells. The invention also provides methods and kits for diagnosis and prognosis of cancer in a subject using cancer stem cell biomarker expression analysis.
    Type: Application
    Filed: April 14, 2008
    Publication date: May 14, 2009
    Applicant: THE JACKSON LABORATORY
    Inventors: Kyuson Yun, Hyuna Yang
  • Patent number: 6602680
    Abstract: The invention features methods and compositions for the production of GABAergic cells, particularly GABAergic neurons. Production of GABAergic cells is accomplished by increasing activity of a Dlx gene (e.g., DLX1, DLX2, or DLX5) in an immature neuronal cell. The increase in Dlx activity causes differentiation of the immature neuronal cell into a neuronal cell exhibiting the GABAergic phenotype. The invention also encompasses use of GABAergic cells produced by the method of the invention in, for example, identification of agents that affect GABAergic cell activity and survival, and in replacement therapy.
    Type: Grant
    Filed: July 5, 2001
    Date of Patent: August 5, 2003
    Assignee: The Regents of the University of California
    Inventors: John L. Rubenstein, Marina Mione, Stewart Anderson, Thorsten Stuehmer, Kyuson Yun
  • Publication number: 20020151066
    Abstract: The invention features methods and compositions for the production of GABAergic cells, particularly GABAergic neurons. Production of GABAergic cells is accomplished by increasing activity of a Dlx gene (e.g., DLX1, DLX2, or DLX5) in an immature neuronal cell. The increase in Dlx activity causes differentiation of the immature neuronal cell into a neuronal cell exhibiting the GABAergic phenotype. The invention also encompasses use of GABAergic cells produced by the method of the invention in, for example, identification of agents that affect GABAergic cell activity and survival, and in replacement therapy.
    Type: Application
    Filed: July 5, 2001
    Publication date: October 17, 2002
    Inventors: John L. Rubenstein, Marina Mione, Stewart Anderson, Thorsten Stuehmer, Kyuson Yun