Abstract: The disclosure provides trispecific and/or trivalent binding proteins comprising four polypeptide chains that form three antigen binding sites that specifically bind one or more target proteins, wherein a first pair of polypeptides forming the binding protein possess dual variable domains having a cross-over orientation and wherein a second pair of polypeptides forming the binding protein possess a single variable domain. The disclosure also provides methods for making trispecific and/or trivalent binding proteins and uses of such binding proteins.

Abstract: Provided herein are trispecific and/or trivalent binding proteins comprising four polypeptide chains that form three antigen binding sites that specifically bind one or more target proteins, wherein a first pair of polypeptides forming the binding protein possess dual variable domains having a cross-over orientation, and wherein and a second pair of polypeptides possess a single variable domain forming a single antigen binding site. In some embodiments, the binding proteins comprise a binding site that binds a CD28 polypeptide, a binding site that binds a CD3 polypeptide, and a binding site that binds a third polypeptide, such as a tumor target protein. In some embodiments, the binding proteins comprise four polypeptide chains that form three antigen binding sites that specifically bind one or more HIV target proteins. The disclosure also relates to methods for making trispecific and/or trivalent binding proteins and uses of such binding proteins.

Abstract: An artificially intelligent harvest and reuse system for planting vegetables has a first mechanic arm moving a plurality of planting plates around a first conveyor, a second conveyor, a first shelf and a second shelf. The planting plates are sent to a connecting conveyor for the grown vegetables thereon to be picked up by a second mechanic arm and further sent to a root cutting apparatus then to a packaging apparatus, while the empty planting plates are further sent to an exit end of the first conveyor and a third mechanic arm places nursery foams with sprouts from a storage area onto the empty planting plates. Then the refilled planting plates are sent back to the corresponding shelf via the second conveyor and placed back into the corresponding layers neatly by the first mechanic arm on a first distributing apparatus.

Abstract: A method for detecting, a roadside object including, a three-dimensional object in the vicinity of a vehicle on a road surface includes recording at least one data set including a plurality of data points associated with a region in a lateral vicinity of the vehicle, the region at least partially including at least one wheel of the vehicle and the road surface, where each data point includes according, to whether it corresponds to the at least one wheel to the road surface or to the roadside object, determining a distance between a data point classified as corresponding to the at least one wheel and a data point classified as corresponding to the roadside object and generating a signal if the distance is below at least one threshold value.

Abstract: In general, the technology relates to a method for displaying objects on a webpage. The method includes receiving a request to transition to the webpage in a web application from a device and in response to the request: obtaining a set of object identifiers, providing the set of object identifiers to a link relationship manager and receiving, from the link relationship manager, a set of link relationships. The method further includes providing the set of link relationships and a link relationship evaluator to the device, where the link relationship evaluator only permits objects that are associated with a link relationship from the set of link relationships to be displayed on the device.

Abstract: The disclosure provides methods of treating viral infection using trispecific binding proteins comprising four polypeptide chains that form three antigen binding sites that specifically bind a CD38 polypeptide (e.g., human and/or cynomolgus monkey CD38 polypeptides), a CD28 polypeptide, and a CD3 polypeptide.

Abstract: In general, the technology relates to a method for displaying objects on a webpage. The method includes receiving a request to transition to the webpage in a web application from a device and in response to the request: obtaining a set of object identifiers, providing the set of object identifiers to a link relationship manager and receiving, from the link relationship manager, a set of link relationships. The method further includes providing the set of link relationships and a link relationship evaluator to the device, where the link relationship evaluator only permits objects that are associated with a link relationship from the set of link relationships to be displayed on the device.

Abstract: In general, the technology relates to a method for displaying objects on a webpage. The method includes receiving a request to transition to the webpage in a web application from a device and in response to the request: obtaining a set of object identifiers, providing the set of object identifiers to a link relationship manager and receiving, from the link relationship manager, a set of link relationships. The method further includes providing the set of link relationships and a link relationship evaluator to the device, where the link relationship evaluator only permits objects that are associated with a link relationship from the set of link relationships to be displayed on the device.

Abstract: The disclosure provides binding proteins that bind CD38 polypeptides, e.g., human and cynomolgus monkey CD38 polypeptides. For example, the binding proteins can be monospecific, bispecific, or trispecific binding proteins with at least one antigen binding domain that binds a CD38 polypeptide. The disclosure also provides methods for making binding proteins that bind CD38 polypeptides and uses of such binding proteins.

Abstract: In general, the technology relates to a method for displaying objects on a webpage. The method includes receiving a request to transition to the webpage in a web application from a device and in response to the request: obtaining a set of object identifiers, providing the set of object identifiers to a link relationship manager and receiving, from the link relationship manager, a set of link relationships. The method further includes providing the set of link relationships and a link relationship evaluator to the device, where the link relationship evaluator only permits objects that are associated with a link relationship from the set of link relationships to be displayed on the device.

Abstract: In general, the technology relates to a method for displaying objects on a webpage. The method includes receiving a request to transition to the webpage in a web application from a device and in response to the request: obtaining a set of object identifiers, providing the set of object identifiers to a link relationship manager and receiving, from the link relationship manager, a set of link relationships. The method further includes providing the set of link relationships and a link relationship evaluator to the device, where the link relationship evaluator only permits objects that are associated with a link relationship from the set of link relationships to be displayed on the device.

Abstract: The disclosure provides trispecific and/or trivalent binding proteins comprising four polypeptide chains that form three antigen binding sites that specifically bind one or more target proteins, wherein a first pair of polypeptides forming the binding protein possess dual variable domains having a cross-over orientation and wherein a second pair of polypeptides forming the binding protein possess a single variable domain. The disclosure also provides methods for making trispecific and/or trivalent binding proteins and uses of such binding proteins.

Abstract: In general, the technology relates to a method for displaying objects on a webpage. The method includes receiving a request to transition to the webpage in a web application from a device and in response to the request: obtaining a set of object identifiers, providing the set of object identifiers to a link relationship manager and receiving, from the link relationship manager, a set of link relationships. The method further includes providing the set of link relationships and a link relationship evaluator to the device, where the link relationship evaluator only permits objects that are associated with a link relationship from the set of link relationships to be displayed on the device.

Abstract: In general, the technology relates to a method for displaying objects on a webpage. The method includes receiving a request to transition to the webpage in a web application from a device and in response to the request: obtaining a set of object identifiers, providing the set of object identifiers to a link relationship manager and receiving, from the link relationship manager, a set of link relationships. The method further includes providing the set of link relationships and a link relationship evaluator to the device, where the link relationship evaluator only permits objects that are associated with a link relationship from the set of link relationships to be displayed on the device.

Abstract: A barbell is provided. The barbell includes a main body and two holding elements. The main body is elongated and hollow to enclose a receiving room. The receiving room is adapted for being filled with fluid or solid. The main body defines a longitudinal direction. The main body is formed with at least one positioning recess on the outer surface thereof. Each holding element is movable sleeved onto the main body. The holding element has a positioning element which is selectively abutted against the positioning recess to position the holding element on the main body. The holding element further has a holding portion for holding.

Abstract: A barbell is provided. The barbell includes a main body and two holding elements. The main body is elongated and hollow to enclose a receiving room. The receiving room is adapted for being filled with fluid or solid. The main body defines a longitudinal direction. The main body is formed with at least one positioning recess on the outer surface thereof. Each holding element is movable sleeved onto the main body. The holding element has a positioning element which is selectively abutted against the positioning recess to position the holding element on the main body. The holding element further has a holding portion for holding.

Abstract: Methods for an oxide layer over an epitaxial layer. In an embodiment, a method includes forming an epitaxial layer of semiconductor material over a semiconductor substrate; forming an oxide layer over the epitaxial layer; applying a solution including an oxidizer to the oxide layer; and cleaning the oxide layer with a cleaning solution. In another embodiment, a densification process is applied to an oxide layer including treating with thermal energy, UV energy, or both. In an embodiment for a gate-all-around device, the cleaning process is applied to an oxide layer over an epitaxial portion of a fin. Additional methods are disclosed.

Abstract: Methods for an oxide layer over an epitaxial layer. In an embodiment, a method includes forming an epitaxial layer of semiconductor material over a semiconductor substrate; forming an oxide layer over the epitaxial layer; applying a solution including an oxidizer to the oxide layer; and cleaning the oxide layer with a cleaning solution. In another embodiment, a densification process is applied to an oxide layer including treating with thermal energy, UV energy, or both. In an embodiment for a gate-all-around device, the cleaning process is applied to an oxide layer over an epitaxial portion of a fin. Additional methods are disclosed.