Patents by Inventor Laurence Burgess

Laurence Burgess has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Materials and methods to potentiate cancer treatment
    Publication number: 20080090782
    Abstract: Compounds that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods to inhibit the DNA-PK biological activity, methods to sensitize cells the agents that cause DNA lesions, and methods to potentiate cancer treatment are disclosed.
    Type: Application
    Filed: February 16, 2007
    Publication date: April 17, 2008
    Applicant: Luitpold Pharmaceuticals, Inc.
    Inventors: James Halbrook, Edward Kesicki, Laurence Burgess, Stephen Schlachter, Charles Eary, Justin Schiro, Hongmei Huang, Michael Evans, Yongxin Han
  • Xanthones, thioxanthones and acridinones as dna-pk inhibitors
    Publication number: 20070167441
    Abstract: Compound that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods of inhibiting the DNA-PK biological activity, methods of sensitizing cells the agents that cause DNA lesions, and methods of potentiating cancer treatment are disclosed.
    Type: Application
    Filed: March 19, 2004
    Publication date: July 19, 2007
    Inventors: James Halbrook, Edward Kesicki, Laurence Burgess, Stephen Schlachter, Charles Eary, Justin Schiro
  • Macrocyclic analogs for the treatment of immunoregulatory disorders and respiratory diseases
    Publication number: 20060160838
    Abstract: Disclosed are compounds of the Formula I and diastereomers, tautomers, solvates, metabolites, and pharmaceutically acceptable salts thereof, wherein X, A, L and Y are as defined herein. Such compounds are useful in the treatment of immunoregulatory and respiratory diseases in mammals. Also disclosed are methods of using such compounds in the treatment of immunoregulatory and respiratory diseases in mammals and pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: January 19, 2006
    Publication date: July 20, 2006
    Inventors: Stephen Schlachter, John Gaudino, Laurence Burgess, Kevin Hunt
  • Cyclic AMP-specific phosphodiesterase inhibitors
    Publication number: 20060074123
    Abstract: Novel pyrrolidine compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases and other diseases involving elevated levels of cytokines, as well as central nervous system (CNS) disorders, also is disclosed.
    Type: Application
    Filed: November 7, 2005
    Publication date: April 6, 2006
    Applicant: ICOS CORPORATION
    Inventors: Timothy Martins, Kerry Fowler, Joshua Odingo, Edward Kesicki, Amy Oliver, Laurence Burgess, John Gaudino, Zachary Jones, Bradley Newhouse, Stephen Schlachter
  • Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases
    Publication number: 20060035821
    Abstract: Provided are novel cyclosporin analogs, methods for their production, and their use for treating immunoregulatory and respiratory diseases, disorders, and conditions.
    Type: Application
    Filed: August 16, 2004
    Publication date: February 16, 2006
    Inventors: Kevin Hunt, Laurence Burgess
  • Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases
    Publication number: 20060035822
    Abstract: Provided are novel cyclosporin analogs, methods for their production, and their use for treating immunoregulatory and respiratory diseases, disorders, and conditions.
    Type: Application
    Filed: August 11, 2005
    Publication date: February 16, 2006
    Inventors: Kevin Hunt, Laurence Burgess
  • Compounds useful for inhibiting CHK1
    Publication number: 20050245525
    Abstract: Aryl- and heteroaryl-substituted urea compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating cancer and other diseases characterized by defects in DNA replication, chromosome segregation, or cell division also are disclosed.
    Type: Application
    Filed: April 27, 2005
    Publication date: November 3, 2005
    Applicant: ICOS CORPORATION
    Inventors: Kathleen Keegan, Edward Kesicki, John Gaudino, Adam Cook, Scott Cowen, Laurence Burgess