Abstract: Stable, topically applicable cosmetic/pharmaceutical skin depigmentation compositions contain a combination depigmentation effective amount of mequinol and adapalene, and optionally, at least one sunscreen, formulated as aqueous-alcoholic gels or gel-creams in topically applicable, physiologically acceptable media therefor.

Abstract: Pharmaceutical cream-gel compositions useful for the treatment of a variety of dermatological conditions, disorders and afflictions, in particular of rosacea, contain at least one avermectin compound active principle, and which also contain an oily phase dispersed in an aqueous phase by means of a non-surfactant polymeric emulsifier, the oily phase comprising oils having a melting point below 30° C. and being free of solid fats having a melting point above 30° C., formulated into a physiologically acceptable medium therefor.

Abstract: A transungual patch/device useful for the treatment of onychomycosis includes: (i) a backing medium; and (ii) an adhesive matrix layer deposited thereon which contains (a) a thus effective amount of amorolfine active agent or derivative thereof essentially uniformly distributed therethrough, dissolved or dispersed in the adhesive, and (b) at least one absorption promoter for enhancing the absorption of the amorolfine or derivative into the nail onto which the patch/device is applied, the at least one absorption promoter comprising either exaltolide alone, or at least two such absorption promoters selected from among urea, N-acetylcysteine and lactic acid.

Abstract: Sprayable pharmaceutical compositions suited for improved transdermal penetration contain a) at least one bioactive agent, notably at least one derivative of vitamin D, (b) at least one volatile silicone and c) a non-volatile oily phase, formulated into d) a pharmaceutically acceptable vehicle therefor.

Abstract: Topically applicable pharmaceutical compositions suited for the treatment of dermatological complaints, conditions or afflictions, notably rosacea, contain a thus effective amount of metronidazole and at least one dye effective to impart a green color thereto, formulated into a topically applicable, pharmaceutically acceptable vehicle therefor.

Abstract: Compositions in the form of a spray contain a pharmaceutical active agent, at least one volatile silicone and a non-volatile oily phase, formulated into a physiologically acceptable medium, are well suited for improved transdermal administration in cosmetics and dermatology.

Abstract: This invention relates to new dermocosmetic and pharmaceutical compositions which are useful for improving and treating hyperreactive skin conditions and more generally allergic-type reactions and/or intolerance phenomena, whether they are caused by external factors or factors intrinsic to the individual. The compositions of this invention preferably contain an anti-radical, in anti-inflammatory and an anti-allergic activity for the treatment of sensitive and/or allergic skin.

Abstract: Topically applicable, stable and non-irritating aqueous-alcoholic cosmetic/dermatological gels suited for cutaneous depigmentation contain water, at least one alcohol, at least one gelling agent, at least one phenolic compound, at least one retinoid, and, optionally, at least one sunscreen, formulated into a topically applicable, physiologically acceptable medium therefor.

Abstract: Solubilized retinoids within cosmetic/pharmaceutical compositions, e.g., aqueous gels or oil-in-water emulsions, are chemically stabilized by introducing therein an amount of at least one base effective to salify such retinoids; the resultant compositions are useful in cosmetics and dermatology, e.g., for treating acne vulgaris or psoriasis.

Abstract: Topically applicable cosmetic/dermatological compositions useful for the treatment of disorders of the skin, notably psoriasis, comprise inverse emulsions containing a glycol or water-glycol dispersed hydrophilic phase, a lipophilic continuous phase, an emulsifier having an HLB of between 2 and 7 and also having calcitriol and clobetasol 17-propionate dissolved therein.

Abstract: Sprayable, anhydrous and physically/chemically stable dermatological/pharmaceutical compositions, well suited for the treatment of a variety of dermatological disorders, notably psoriasis, contain: a) a therapeutically effective amount of a solubilized corticoid, notably dissolved clobetasol propionate; b) a therapeutically effective amount of a solubilized vitamin D derivative, notably dissolved calcitriol; and c) an oily phase which comprises one or more oils; formulated into d), a sprayable and topically applicable, dermatologically/pharmaceutically acceptable vehicle therefor.

Abstract: Topically applicable dermatological/cosmetic compositions suited for ungual/peri-ungual administration for the treatment of a variety of pathologies, including fungal pathologies, such as onychomycosis, contain (a) at least one biologically active agent (e.g., antifungal) and (b) at least two of the pro-penetrating agents selected from the group consisting of urea, an organic acid and an ethoxydiglycol, the at least two-pro-penetrating agents respectively being present in effective amounts as to synergistically improve the ungual/peri-ungual bioavailability of the at least one biologically active agent.

Abstract: Stable, recrystallization-resistant invert emulsions, suited, e.g., for preventing/treating the signs of chronological or actinic skin aging and for preventing/treating atrophy of the skin or mucous membranes, comprise a cosmetically/therapeutically effective amount of DHEA and/or chemical and/or biological precursor or derivative thereof, such invert emulsions also comprising a glycolic or hydroglycolic dispersed hydrophilic phase, a lipophilic continuous phase and an emulsifier having an HLB ranging from 2 to 7.

Abstract: The present invention relates to the use of at least two compounds chosen from components having an a) anti-radical, b) anti-inflammatory and c) anti-allergic activity for the preparation of a composition exhibiting at least two of the a), b) and c) activities intended for the treatment of sensitive and/or allergic skin. It also relates to a process for the preparation of such compositions and to the compositions thus obtained.