Patents by Inventor Laurent Mauclaire

Laurent Mauclaire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound for chelating a metal, radiopharmaceutical, manufacturing process therefor, and diagnostic kit
    Publication number: 20040043920
    Abstract: The present invention provides a compound for chelating a metal or a metal complex, characterized in that it consists of a bis-dithiocarbamate structure (F) having the formula below: 1
    Type: Application
    Filed: May 28, 2003
    Publication date: March 4, 2004
    Inventors: Laurent Mauclaire, Eric Berthommier
  • Tropane derivatives useable in particular for in vivo detection of dopamine transporters
    Patent number: 6180083
    Abstract: The present invention relates to tropane derivatives having particular use for the in vivo detection of dopamine transporters. These derivatives meet the formula in which R1 is I or Sn (R3)3, R2 is for example the methyl group, and X and Y are various substituents. The derivatives with X═CH3 and Y═H show strong specificity for the dopamine transporter compared with the serotonin transporter (74% inhibition when the transporter is previously saturated with GBR 12909).
    Type: Grant
    Filed: November 10, 1998
    Date of Patent: January 30, 2001
    Assignee: CIS bio International
    Inventors: Laurent Mauclaire, Patrick Emond, Denis Guilloteau, Jean-Claude Besnard, Yves Frangin
  • Radiopharmaceutical compositions that include an inclusion complex of a cyclodextrin and a radio-halogenated fatty acid
    Patent number: 5993776
    Abstract: The invention relates to radio-pharmaceutical compositions that include an inclusion complex of a cyclodextrin and a radio-halogenated fatty acid.These complexes include a cyclodextrin such as .beta.-cyclodextrin, .gamma.-cyclodextrin and their derivatives, and a radio-halogenated fatty acid, in particular a fatty acid labelled with radioactive iodine such as 16-iodo 3-methyl hexadecanoic acid suitable for the examination of the myocardium by scintigraphy.The cyclodextrin allows the fatty acid to dissolve in aqueous solution without any addition of human blood albumin, while further improving the biodistribution of the fatty acid and its stability to heat.
    Type: Grant
    Filed: May 14, 1997
    Date of Patent: November 30, 1999
    Assignee: CIS bio International
    Inventors: Roberto Pasqualini, Bruno Perly, Laurent Mauclaire, Florence Djedaini-Pilard, Yves Michel
  • Derivatives of porphyrin and metalloporphyrins optionally coupled to a biologically active molecule and pharmaceutical composition containing them
    Patent number: 5268371
    Abstract: The present invention relates to metallized porphyrin derivatives having the formula: ##STR1## wherein the R and M variables are as defined in the specification. Said porphyrin derivatives having uses as antitumor agents, diagnostics agents, or in therapy.
    Type: Grant
    Filed: September 10, 1992
    Date of Patent: December 7, 1993
    Assignee: CIS bio International
    Inventors: Laurent Mauclaire, Catherine Bedel, Michel Pereyre, Jean-Claude Saccavini