Patents by Inventor Lee Kim Swee

Lee Kim Swee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190359933
    Abstract: Non-genetically engineered mammalian cells modified by sortase-mediated conjugation of an agent thereto are provided. Methods of conjugating agents to non-genetically engineered mammalian cells using sortase are provided. Methods of using the cells, e.g., for diagnostic and/or therapeutic purposes, are provided.
    Type: Application
    Filed: April 11, 2019
    Publication date: November 28, 2019
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: Lee Kim Swee, Hidde L. Ploegh
  • Publication number: 20190256818
    Abstract: Non-genetically engineered mammalian cells modified by sortase-mediated conjugation of an agent thereto are provided. Methods of conjugating agents to non-genetically engineered mammalian cells using sortase are provided. Methods of using the cells, e.g., for diagnostic and/or therapeutic purposes, are provided.
    Type: Application
    Filed: February 15, 2019
    Publication date: August 22, 2019
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: Lee Kim Swee, Hidde L. Ploegh
  • Patent number: 10260038
    Abstract: Non-genetically engineered mammalian cells modified by sortase-mediated conjugation of an agent thereto are provided. Methods of conjugating agents to nongenetically engineered mammalian cells using sortase are provided. Methods of using the cells, e.g. a method of modulating an immune response of a subject to an entity of interest, a method of neutralizing a substance in the body of a subject, a method of treating a subject in need of treatment for deficiency of a protein, and a method of treating a subject in need of treatment for a disease, are provided.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: April 16, 2019
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Lee Kim Swee, Hidde L. Ploegh
  • Publication number: 20160122707
    Abstract: Non-genetically engineered mammalian cells modified by sortase-mediated conjugation of an agent thereto are provided. Methods of conjugating agents to nongenetically engineered mammalian cells using sortase are provided. Methods of using the cells, e.g. a method of modulating an immune response of a subject to an entity of interest, a method of neutralizing a substance in the body of a subject, a method of treating a subject in need of treatment for deficiency of a protein, and a method of treating a subject in need of treatment for a disease, are provided.
    Type: Application
    Filed: May 9, 2014
    Publication date: May 5, 2016
    Applicant: WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Lee Kim Swee, Hidde L. Ploegh