Patents by Inventor Leif R. Sloan
Leif R. Sloan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11786729Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.Type: GrantFiled: June 15, 2021Date of Patent: October 17, 2023Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Bradford Evan Gliner, Allen Wyler, Brad Fowler, W. Douglas Sheffield, Richard Kuntz, Kent Leyde, Leif R. Sloan
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Publication number: 20210308456Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.Type: ApplicationFiled: June 15, 2021Publication date: October 7, 2021Inventors: Bradford Evan Gliner, Allen Wyler, Brad Fowler, W. Douglas Sheffield, Richard Kuntz, Kent Leyde, Leif R. Sloan
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Patent number: 11065449Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.Type: GrantFiled: November 6, 2017Date of Patent: July 20, 2021Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Bradford Evan Gliner, Allen Wyler, Brad Fowler, W. Douglas Sheffield, Richard Kuntz, Kent Leyde, Leif R. Sloan
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Publication number: 20180359332Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.Type: ApplicationFiled: November 6, 2017Publication date: December 13, 2018Inventors: Bradford Evan Gliner, Allen Wyler, Brad Fowler, W. Douglas Sheffield, Richard Kuntz, Kent Leyde, Leif R. Sloan
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Publication number: 20180167482Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.Type: ApplicationFiled: November 6, 2017Publication date: June 14, 2018Inventors: Bradford Evan Gliner, Allen Wyler, Brad Fowler, W. Douglas Sheffield, Richard Kuntz, Kent Leyde, Leif R. Sloan
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Patent number: 9808627Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.Type: GrantFiled: November 16, 2015Date of Patent: November 7, 2017Assignee: ADVANCED NEUROMODULATION SYSTEMS, INC.Inventors: Bradford Evan Gliner, Allen Wyler, Brad Fowler, W. Douglas Sheffield, Richard Kuntz, Kent Leyde, Leif R. Sloan
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Publication number: 20160067496Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.Type: ApplicationFiled: November 16, 2015Publication date: March 10, 2016Inventors: Bradford Evan Gliner, Allen Wyler, Brad Fowler, W. Douglas Sheffield, Richard Kuntz, Kent Leyde, Leif R. Sloan
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Patent number: 9186510Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.Type: GrantFiled: December 9, 2013Date of Patent: November 17, 2015Assignee: ADVANCED NEUROMODULATION SYSTEMS, INC.Inventors: Bradford Evan Gliner, Allen Wyler, Brad Fowler, W. Douglas Sheffield, Richard Kuntz, Kent Leyde, Leif R. Sloan
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Patent number: 8929991Abstract: Methods for establishing parameters for neural stimulation, including via performance of working memory tasks, and associated kits, are disclosed. A method in accordance with one embodiment includes engaging a patient in a function controlled at least in part by a target neural population, and applying electromagnetic signals to the target neural population. A target parameter in accordance with which the electromagnetic signals are applied is adjusted, based at least in part on a characteristic of the patient's performance of the function. Electromagnetic signals are applied to the patient with the adjusted target parameter, and the patient's response to the electromagnetic signals, including the characteristic of the patient's performance, is evaluated.Type: GrantFiled: April 19, 2007Date of Patent: January 6, 2015Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Brad Fowler, Leif R. Sloan, Joleen Borgerding
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Patent number: 8926676Abstract: Systems and methods for applying signals, including contralesional electromagnetic signals, to neural populations, are disclosed. A particular method can be directed to treating a patient having a subject neural population in a first (e.g., ipsilesional) hemisphere of the brain, with the subject neural population having, or previously having, a functionality capable of being improved. The method can include directing an application of electromagnetic signals at least proximate to a target neural population at a second (e.g., contralesional) hemisphere of the brain to at least constrain a functionality of the target neural population, which has transcallosal communication with the first hemisphere.Type: GrantFiled: April 6, 2007Date of Patent: January 6, 2015Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Alvaro Pascual-Leone, Bradford E. Gliner, David Himes, Leif R. Sloan
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Publication number: 20140222113Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.Type: ApplicationFiled: December 9, 2013Publication date: August 7, 2014Applicant: Advanced Neuromodulation Systems, Inc., d/b/a St. Jude Medical Neuromodulation DivisionInventors: Bradford Evan Gliner, Allen Wyler, Brad Fowler, W. Douglas Sheffield, Richard Kuntz, Kent Leyde, Leif R. Sloan
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Patent number: 8706241Abstract: Systems and methods for patient interactive neural stimulation and/or chemical substance delivery are disclosed. A method in accordance with one embodiment of the invention includes affecting a target neural population of the patient by providing to the patient at least one of an electromagnetic signal and a chemical substance. The method can further include detecting at least one characteristic of the patient, with the characteristic at least correlated with the patient's performance of an adjunctive therapy task that is performed in association with affecting the target neural population. The method can still further include controlling at least one parameter in accordance with which the target neural population is affected, based at least in part on the detected characteristic.Type: GrantFiled: December 20, 2010Date of Patent: April 22, 2014Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Andrew D Firlik, Bradford Evan Gliner, W Douglas Sheffirld, Leif R Sloan
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Patent number: 8606361Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.Type: GrantFiled: July 8, 2011Date of Patent: December 10, 2013Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Bradford Evan Gliner, Allen Wyler, Brad Fowler, W. Douglas Sheffield, Richard Kuntz, Kent Leyde, Leif R. Sloan
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Patent number: 8538537Abstract: Systems and methods for providing targeted neural stimulation therapy to address neurological disorders, including neuropsychiatric and neuropsychological disorders are disclosed. A method for treating a patient's neurological disorder in accordance with a particular embodiment includes, in a patient identified as having at least one of a neuropsychological disorder and a neuropsychiatric disorder, implanting at least one stimulation electrode within the patient's skull cavity, and outside a cortical surface of the patient's brain. The electrode is implanted at a location in a range of about 15 mm to about 35 mm anterior to a precentral sulcus reference point that is positioned at the precentral sulcus and at the patient's middle frontal gyrus. The method can further include treating the patient's disorder by applying electrical stimulation to the patient via the at least one stimulation electrode.Type: GrantFiled: December 8, 2008Date of Patent: September 17, 2013Assignee: Advanced Neuromodulations Systems, Inc.Inventors: Justin Hulvershorn, Brad Fowler, Bradford Evan Gliner, Leif R. Sloan, Brian Kopell, David Alan Soltysik
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Publication number: 20120078327Abstract: Microdevice-based electrode assemblies and associated neurostimulation systems, devices and methods are disclosed. A system in accordance with a particular embodiment includes a microdevice positioned to send signals or fluids to the patient, and/or to receive signals or fluids from the patient. The microdevice can include a housing having an external surface, and a signal/fluid transmitter/receiver positioned within the housing and coupled to a terminal carried by the housing. The system can further include a patient-implantable, flexible support member attached to the external surface of the housing and carrying the housing. The system can still further include an interface carried by the support member and connected to the terminal, with the interface being positioned to direct signals or fluids into patient tissue, and/or receive signals or fluids from the patient tissue.Type: ApplicationFiled: December 1, 2011Publication date: March 29, 2012Inventors: Leif R. Sloan, Brad Fowler
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Publication number: 20120041498Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.Type: ApplicationFiled: July 8, 2011Publication date: February 16, 2012Inventors: Bradford Evan Gliner, Allen Wyler, Brad Fowler, W. Douglas Sheffield, Richard Kuntz, Kent Leyde, Leif R. Sloan
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Patent number: 8090446Abstract: Methods for providing electrical stimulation therapy to a cortex of a patient via a plurality of electrodes proximate to the cortex and a pulse generator implanted in the patient. One embodiment of a method in accordance with the invention comprises determining whether the current applied via the plurality of electrodes results in a sufficient current density in the cortex. The current density, for example, may need to be high enough to induce a response in the patient for determining the activation threshold of the specific stimulation site, or the current density may need to be high enough to perform a specific therapy. If the current density is not sufficient, the method continues by selecting a subset of the plurality of electrodes, and applying electrical current to the cortex via the subset of the electrodes.Type: GrantFiled: April 8, 2008Date of Patent: January 3, 2012Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Brad Fowler, Justin Hulvershorn, Bradford E. Gliner, Leif R. Sloan
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Patent number: 7983762Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.Type: GrantFiled: December 3, 2008Date of Patent: July 19, 2011Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Bradford Evan Gliner, Allen Wyler, Brad Fowler, W. Douglas Sheffield, Richard Kuntz, Kent Leyde, Leif R. Sloan
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Publication number: 20110092882Abstract: Systems and methods for patient interactive neural stimulation and/or chemical substance delivery are disclosed. A method in accordance with one embodiment of the invention includes affecting a target neural population of the patient by providing to the patient at least one of an electromagnetic signal and a chemical substance. The method can further include detecting at least one characteristic of the patient, with the characteristic at least correlated with the patient's performance of an adjunctive therapy task that is performed in association with affecting the target neural population. The method can still further include controlling at least one parameter in accordance with which the target neural population is affected, based at least in part on the detected characteristic.Type: ApplicationFiled: December 20, 2010Publication date: April 21, 2011Inventors: Andrew D. Firlik, Bradford Evan Gliner, W. Douglas Sheffield, Leif R. Sloan
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Patent number: 7856264Abstract: Systems and methods for patient interactive neural stimulation and/or chemical substance delivery are disclosed. A method in accordance with one embodiment of the invention includes affecting a target neural population of the patient by providing to the patient at least one of an electromagnetic signal and a chemical substance. The method can further include detecting at least one characteristic of the patient, with the characteristic at least correlated with the patient's performance of an adjunctive therapy task that is performed in association with affecting the target neural population. The method can still further include controlling at least one parameter in accordance with which the target neural population is affected, based at least in part on the detected characteristic.Type: GrantFiled: October 19, 2005Date of Patent: December 21, 2010Assignee: Advanced Neuromodulation Systems, Inc.Inventors: Andrew D. Firlik, Bradford Evan Gliner, W. Douglas Sheffield, Leif R. Sloan