Patents by Inventor Leonardo V. NICACIO

Leonardo V. NICACIO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING CANCER WITH A COMBINATION OF A PLATINUM-BASED AGENT AND AN ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATE
    Publication number: 20220387485
    Abstract: The invention provides a platinum-based agent (e.g., carboplatin) in combination with an antibody-drug conjugate that binds to tissue factor (TF) (e.g., tisotumab vedotin) and their use in methods of treating cancer, such as bladder cancer and cervical cancer. The invention also provides compositions and kits comprising the platinum-based agent (e.g., carboplatin) and the antibody-drug conjugate that binds to TF (e.g., tisotumab vedotin) for use in treating cancer, such as bladder cancer and cervical cancer.
    Type: Application
    Filed: November 6, 2020
    Publication date: December 8, 2022
    Applicant: Genmab A/S
    Inventors: Reshma A RANGWALA, Esther C,W. BREIJ, Sandra VERPLOEGEN, Oyewale O. ABIDOYE, Leonardo V. NICACIO
  • ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND THEIR USE IN THE TREATMENT OF CANCER
    Publication number: 20210308208
    Abstract: The invention provides methods and compositions for treating cancer, such as ovarian cancer, peritoneal cancer, and fallopian tube cancer, in a subject, such as by the administration of antibody-drug conjugates that bind to tissue factor (TF). The invention also provides articles of manufacture and compositions comprising said antibody drug-conjugates that bind to TF for use in treating cancer (e.g., ovarian cancer, peritoneal cancer, and fallopian tube cancer).
    Type: Application
    Filed: August 14, 2019
    Publication date: October 7, 2021
    Inventors: Reshma A. RANGWALA, Esther C.W. BREIJ, Sandra VERPLOEGEN, Bart DE GOEIJ, Oyewale O. ABIDOYE, Leonardo V. NICACIO, Stephen C. ALLEY