Abstract: An atrial shunt regulation device, a braid tool and a braid method thereof. The left disk (1) and the right disk (2) of the atrial shunt regulation device are connected via the intermediate portion (3) as a single piece, and the left disk (1), the intermediate portion (3) and the right disk (2) are braided by a single braid wire (10). The ends of the braid wires are secured by one nut in the single-braid method, which reduces the number and size of the nuts and easily forms a cortical layer. The braid tool for braiding an atrial shunt regulation device comprises a cylinder braid body mold (20), the cylindrical braid body mold (20) includes positioning pins (21) that are evenly connected to an outer wall of the braid body mold. The braid method of the atrial shunt regulation device comprises braiding, thermoforming, braiding a binding-off wire, securing ends of wires by a nut, and thermoforming again.

Abstract: Provided herein are crystalline forms of a triazolopyrimidine compound, which is useful for treating a PRC2-mediated disease or disorder.

Abstract: Provided herein are compositions of an antiviral therapeutic to treat influenza suitable for administration via inhalation.

Abstract: Provided herein are crystalline forms of a triazolopyrimidine compound, which is useful for treating a PRC2-mediated disease or disorder.

Abstract: Provided herein are crystalline forms of a triazolopyrimidine compound, which is useful for treating a PRC2-mediated disease or disorder.

Abstract: Provided herein are crystalline forms of a triazolopyrimidine compound, which is useful for treating a PRC2-mediated disease or disorder.

Abstract: The present invention provides a compound of formula A: or a pharmaceutically acceptable salt thereof, wherein B, Q, R1, R5, R6, R7, R8 and Z are defined herein, which is a 2?-branched nucleoside useful for the treatment or prevention of viral infections, particularly dengue virus, yellow fever virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis, St Louis encephalitis, Omsk hemorrhagic fever virus, bovine viral diarrhea virus, Zika virus and Hepatitis C virus.

Abstract: The present invention provides a compound of formula A: or a pharmaceutically acceptable salt thereof, wherein B, Q, R1, R5, R6, R7, R8 and Z are defined herein, which is a 2?-branched nucleoside useful for the treatment or prevention of viral infections, particularly dengue virus, yellow fever virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis, St Louis encephalitis, Omsk hemorrhagic fever virus, bovine viral diarrhea virus, Zika virus and Hepatitis C virus.

Abstract: The present invention provides a compound of formula A: or a pharmaceutically acceptable salt thereof, wherein B, Q, R1, R5, R6, R7, R8 and Z are as defined herein, which is a 2?-branched nucleoside useful for the treatment or prevention of viral infections, particularly dengue fever, yellow fever, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis, St Louis encephalitis, Omsk hemorrhagic fever virus, bovine viral diarrhea virus, Zika virus and Hepatitis C virus.

Abstract: The present invention provides a compound of formula A: or a pharmaceutically acceptable salt thereof, wherein B, Q, R1, R5, R6, R7, R8 and Z are as defined herein, which is a 2?-branched nucleoside useful for the treatment or prevention of viral infections, particularly dengue fever, yellow fever, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis, St Louis encephalitis, Omsk hemorrhagic fever virus, bovine viral diarrhea virus, Zika virus and Hepatitis C virus.

Abstract: The invention relates to compounds of formula (I): as described herein, pharmaceutical preparations comprising such compounds, uses and methods of use for such compounds in the treatment of a disorder or a disease mediated by the activity of MDM2 and/or MDM4, and combinations comprising such compounds.

Abstract: In a virtual environment, a virtual machine (VM) host creates and displays one or more application shortcuts in the VM host. An application shortcut correlates to a software application that is installed in a VM guest. When the VM host receives an execution command for the application shortcut from the VM host, the VM host establishes a connection channel between the VM host and the VM guest and transmits a launch request to the VM guest via the connection channel. The VM guest launches the software application in response to the launch request.

Abstract: The invention relates to compounds of formula (I): as described herein, pharmaceutical preparations comprising such compounds, uses and methods of use for such compounds in the treatment of a disorder or a disease mediated by the activity of MDM2 and/or MDM4, and combinations comprising such compounds.

Abstract: The invention relates to compounds of formula (I): as described herein, pharmaceutical preparations comprising such compounds, uses and methods of use for such compounds in the treatment of a disorder or a disease mediated by the activity of MDM2 and/or MDM4, and combinations comprising such compounds.

Abstract: A computer includes a switch, a power supply, a TV module, a computer module and a control module. The switch creates a trigger signal. The TV module plays TV programs. The control module controls the power supply to power on the TV module after receiving the trigger signal when the control module determines the TV module and the computer module are powered off.

Abstract: A control circuit and method for a LED driver accurately control the output current of the LED driver by adjusting a reference voltage or a feedback voltage according to the input voltage of the LED driver such that the output current decreases with the decrease of the input voltage. Therefore, it enhances the efficiency of the LED driver and maximizes the battery use time of a battery powered system.

Abstract: A method for storing files in a storage device includes the following steps. The storage device is divided into an original partition and a system partition. A plurality of original files is installed in the original partition. A shortcut is established in the system partition pointing to a first original file of the original files. The first original file can be executed by activating the shortcut.

Abstract: A computer includes a switch, a power supply, a TV module, a computer module and a control module. The switch creates a trigger signal. The TV module plays TV programs. The control module controls the power supply to power on the TV module after receiving the trigger signal when the control module determines the TV module and the computer module are powered off.

Abstract: In a virtual environment, a virtual machine (VM) host creates and displays one or more application shortcuts in the VM host. An application shortcut correlates to a software application that is installed in a VM guest. When the VM host receives an execution command for the application shortcut from the VM host, the VM host establishes a connection channel between the VM host and the VM guest and transmits a launch request to the VM guest via the connection channel. The VM guest launches the software application in response to the launch request.

Abstract: An electronic book reader includes a text obtaining module, a text analysis module, a speech synthesis module, a control module, and an audio output device. The text obtaining module is used for obtaining a selected segment of a text. The text analysis module is used for analyzing a time phrase of the selected segment to obtain a waiting time period according to meaning of the time phrase in the selected segment. The speech synthesis module is used for converting the selected segment into speech. The control module is used for sending the content of the selected segment to the speech synthesis module. Wherein the control module waits for the waiting time period after sending the time phrase to the speech synthesis. The audio output module is used for playing the speech.