Patents by Inventor Lianshan Yan

Lianshan Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190225698
    Abstract: An anti-CD27 antibody, an antigen-binding fragment thereof, and a medical use of the same are described. Further, provided are a chimeric antibody comprising a CDR of the anti-CD27 antibody, a humanized antibody, a pharmaceutical composition comprising a human anti-CD27 antibody or an antigen-binding fragment thereof, and use of the same as an anti-cancer drug. The present invention particularly relates to a human anti-CD27 antibody and use thereof in preparing a drug for treating a CD27-mediated disease or disorder.
    Type: Application
    Filed: September 28, 2017
    Publication date: July 25, 2019
    Inventors: Shude YAN, Jiahua JIANG, Lianshan ZHANG, Guoqing CAO
  • Patent number: 8073326
    Abstract: Devices, systems and techniques for optical communication are provided based on polarization division multiplexing (PDM) to use an optical monitor channel at a distinct optical monitor wavelength to monitor optical polarization fluctuation and polarization mode dispersion during the transmission from the transmitter to the receiver to facilitate the effective demultiplexing of the two orthogonal signal channels at the receiver through automatic feedback control on a dynamic polarization controller and a polarization beam splitter.
    Type: Grant
    Filed: December 3, 2007
    Date of Patent: December 6, 2011
    Assignee: General Photonics Corporation
    Inventors: Lianshan Yan, Xiaotian Steve Yao
  • Patent number: 7952711
    Abstract: Systems, apparatus and methods for characterizing linear retarders using a waveplate analyzer constructed by polarization rotators. In one implementation of such an analyzer, both the retardation of the waveplate sample and the orientation of optical axis of the waveplate sample can be simultaneously measured.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: May 31, 2011
    Assignee: General Photonics Corporation
    Inventors: Xiaojun Chen, Lianshan Yan, Xiaotian Steve Yao
  • Patent number: 7945130
    Abstract: Apparatus and methods for scrambling optical modes in multimode fibers to achieve uniform light distribution in guided multi-mode light for various applications.
    Type: Grant
    Filed: November 15, 2007
    Date of Patent: May 17, 2011
    Assignee: General Photonics Corporation
    Inventors: Lianshan Yan, Lynn Lin, Xiaojun Chen, Xiaotian Steve Yao
  • Publication number: 20100290738
    Abstract: Apparatus and methods for scrambling optical modes in multimode fibers to achieve uniform light distribution in guided multi-mode light for various applications.
    Type: Application
    Filed: November 15, 2007
    Publication date: November 18, 2010
    Inventors: Lianshan Yan, Lynn Lin, Xiaojun Chen, Xiaotian Steve Yao
  • Patent number: 7724435
    Abstract: Devices and their operations to use multiple adjustable differential group delay (DGD) elements in various applications including tunable PMD emulators and compensators for producing different PMD profiles with an adjustable average DGD value.
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: May 25, 2010
    Assignee: General Photonics Corporation
    Inventors: Lianshan Yan, X. Steve Yao
  • Patent number: 7723670
    Abstract: Differential group delay (DGD) devices and techniques based on folded optical paths. An in-line polarization monitor can be provided as a feedback for worst-case alignment without using an in-line polarizer. Polarization maintaining retro reflectors can minimize the introduced higher-order polarization effects caused by reflections between folding mirrors or prisms in conventional schemes.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: May 25, 2010
    Assignee: General Photonics Corporation
    Inventors: Lianshan Yan, Xiaojun Chen, Xiaotian Steve Yao
  • Patent number: 7693419
    Abstract: Techniques and devices that use polarization rotation and optical interferometry to provide optical spectrum analysis of an optical signal.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: April 6, 2010
    Assignee: General Photonics Corporation
    Inventors: Xiaojun Chen, Lianshan Yan, X. Steve Yao
  • Patent number: 7436569
    Abstract: Devices and techniques for generating and analyzing states of polarization in light using multiple adjustable polarization rotators in various applications.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: October 14, 2008
    Assignee: General Photonics Corporation
    Inventors: X. Steve Yao, Xiaojun Chen, Lianshan Yan
  • Publication number: 20080138070
    Abstract: Apparatus, systems and techniques for optical communication based on polarization division multiplexing (PDM) using an optical monitor channel to facilitate the effective demultiplexing of the two orthogonal signal channels through automatic feedback control on a dynamic polarization controller and a polarization beam splitter.
    Type: Application
    Filed: December 3, 2007
    Publication date: June 12, 2008
    Inventors: Lianshan Yan, Xiaotian Steve Yao
  • Publication number: 20080038000
    Abstract: A multi-wavelength optical signal copropagates through a fiber-optic communication link with a continuous-wave ancillary wavelength having an unknown state of polarization (SOP), which is scrambled periodically in time. The instantaneous value of polarization dependent loss (PDL) in the ancillary wavelength is monitored in real time, and is used as an error signal to adjust at least one polarization controller. Polarization scrambling is performed by periodically changing the SOP with time, such that the polarization-scrambled optical signal covers approximately an entire Poincaré sphere surface, preferably uniformly, during each time period. At an optical node between fibers, an adjustable PDL compensator contains two ordered pairs each consisting of one polarization controller and one optical element introducing fixed PDL.
    Type: Application
    Filed: April 16, 2007
    Publication date: February 14, 2008
    Applicant: University of Southern California (LA)
    Inventors: Qian Yu, Lianshan Yan, Alan Willner
  • Publication number: 20070223078
    Abstract: Devices and techniques for generating and analyzing states of polarization in light using multiple adjustable polarization rotators in various applications.
    Type: Application
    Filed: July 28, 2006
    Publication date: September 27, 2007
    Inventors: X. Yao, Xiaojun Chen, Lianshan Yan
  • Patent number: 7227686
    Abstract: Tunable PMD emulators and compensators for producing different PMD profiles with an adjustable average DGD value.
    Type: Grant
    Filed: March 8, 2005
    Date of Patent: June 5, 2007
    Assignee: General Photonics Corporation
    Inventors: Lianshan Yan, X. Steve Yao
  • Patent number: 7206517
    Abstract: A multi-wavelength optical signal copropagates through a fiber-optic communication link with a continuous-wave ancillary wavelength having an unknown state of polarization (SOP), which is scrambled periodically in time. The instantaneous value of polarization dependent loss (PDL) in the ancillary wavelength is monitored in real time, and is used as an error signal to adjust at least one polarization controller. Polarization scrambling is performed by periodically changing the SOP with time, such that the polarization-scrambled optical signal covers approximately an entire Poincaré sphere surface, preferably uniformly, during each time period. At an optical node between fibers, an adjustable PDL compensator contains two ordered pairs each consisting of one polarization controller and one optical element introducing fixed PDL.
    Type: Grant
    Filed: March 15, 2002
    Date of Patent: April 17, 2007
    Assignee: University of Southern California (LA)
    Inventors: Qian Yu, Lianshan Yan, Alan E. Willner
  • Publication number: 20060244951
    Abstract: Autocorrelation technique for measurement of width of optical short pulses based on polarization effects. The optical pulse is split into two orthogonal polarization states and these two replicas have a relative delay which depolarizes the pulse. By tuning the relative delay of the two replicas and measuring the degree-of-polarization (DOP) of the pulse or the induced polarimetric four-wave mixing (FWM) through nonlinear media, the pulse's temporal width can be accurately derived. The technique can be all-fiber-based, wavelength independent, cost effective, applicable to low optical power, and does not require significant optical alignment.
    Type: Application
    Filed: March 3, 2006
    Publication date: November 2, 2006
    Applicant: University of Southern California
    Inventors: Ting Luo, Changyuan Yu, Zhongqi Pan, Lianshan Yan, Saurabh Kumar, Alan Willner
  • Patent number: 7067795
    Abstract: Techniques and systems for dynamically controlling polarization of an optical signal by using various feedback controls, and by combining both feed-forward and feedback controls. Various dynamic control algorithms for such systems and other optical systems have been disclosed.
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: June 27, 2006
    Assignee: General Photonics Corporation
    Inventors: Lianshan Yan, X. Steve Yao, Yongqiang Shi
  • Patent number: 7035538
    Abstract: Techniques for monitoring frequency-dependent parameter and optical property such as optical dispersion in a modulated optical signal with sidebands based on optical vestigial sideband filtering. Monitoring implementations for both chromatic dispersion and polarization-mode dispersion are described as examples.
    Type: Grant
    Filed: July 8, 2002
    Date of Patent: April 25, 2006
    Assignee: University of Southern California
    Inventors: Alan E. Willner, Qian Yu, Zhongqi Pan, Lianshan Yan
  • Patent number: 6975454
    Abstract: An optical device including a beam splitter, polarization controller, and beam combiner is described. In some embodiments, the beam splitter and beam combiner are provided in a single element. An incoming light beam is split into two beams with different polarization components. The polarization of one or both of the beams is rotated using one or two polarization controllers such as fiber squeezers. The beams are then combined, so that a portion of each of the beams is provided to an output. The polarization dependent loss of the device can then be controlled by controlling the polarization rotation. In some embodiments, the rotation is dynamically controlled.
    Type: Grant
    Filed: July 31, 2002
    Date of Patent: December 13, 2005
    Assignee: General Photonics Corporation
    Inventors: Lianshan Yan, X. Steve Yao
  • Publication number: 20040114857
    Abstract: A method for tunable optical pulse width generation comprises varying chirp of the signal of the pulse and concurrently varying dispersion of the signal. A system for tunable pulse width generation comprises a phase modulator providing the chirp modulation by modulating peak to peak phase of an optical signal and a tunable dispersion element providing the chromatic dispersion to the optical signal. A system for tunable pulse width return to zero optical signal transmission comprises at least one optical signal, a plurality of amplitude modulators for modulating the signal and a tunable pulse width generator comprising a phase modulator providing the chirp modulation and a tunable dispersion element providing the dispersion.
    Type: Application
    Filed: March 19, 2003
    Publication date: June 17, 2004
    Inventors: Lianshan Yan, Reza Motaghian Nezam, Alan E. Willner
  • Patent number: 6654103
    Abstract: Techniques and devices for controlling or compensating for both the first-order and high-order PMD effects in an optical signal by processing the signal in a fixed DGD stage and a variable DGD stage in sequence.
    Type: Grant
    Filed: September 4, 2001
    Date of Patent: November 25, 2003
    Assignee: University of Southern California
    Inventors: Qian Yu, Lianshan Yan, Sanggeon Lee, Alan E. Willner