Patents by Inventor Lili Cheng

Lili Cheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210077637
    Abstract: The present disclosure provides a pH and oxygen dual-sensitive magnetic resonance imaging contrast agent and a preparation method thereof, which is a dual-modal nanoparticle contrast agent with 19F signal and CEST dual signal (19F-CEST), a CEST contrast agent that is dual-sensitive to pH and oxygen. The preparation method comprises: mixing a variety of phospholipid surfactants and cholesterol well to obtain a blend of phospholipid surfactants, which is dissolved in chloroform or a mixed solvent of chloroform and methanol, evaporated to dryness with a rotary evaporator and dried overnight in a vacuum oven at 40° C. after adding rhodamine, finally, it is dispersed in water containing glycerin by mechanical dispersion or ultrasonic vibration to obtain a lipid modifier; mixing perfluorocarbon, the lipid modifier obtained in step (1), glycerin, and water and ultrasonically mixing well with a probe, and extruding with an extruder to prepare a perfluorocarbon nanoemulsion.
    Type: Application
    Filed: September 30, 2020
    Publication date: March 18, 2021
    Inventors: Xinlin Sun, Lina Wu, Rong A, OLAGBAJU OLUWATOSIN ATINUKE, Kai Wang, Lili Yang, Lixin Cheng, Wenju Qiao, Xiaohong Sun
  • Publication number: 20210035689
    Abstract: The present disclosure proposes a modeling method and apparatus for diagnosing an ophthalmic disease based on artificial intelligence, and a storage medium. The modeling method includes: establishing a data collection of ophthalmic images and a data collection of non-image ophthalmic disease diagnosis questionnaires; training a first neural network model by employing the data collection of the ophthalmic images to obtain a first classification model; training a second classification model by employing the data collection of non-image ophthalmic disease diagnosis questionnaires; and merging the first classification model and the second classification model to obtain a target classification network model, in which, a test result outputted by the target classification network model is used as a diagnosis result of the ophthalmic disease.
    Type: Application
    Filed: April 17, 2018
    Publication date: February 4, 2021
    Inventors: Xiaoqing Liu, Jiaxu Hong, Yong Ni, Shuangshuang Li, Lili Wang, Wei He, Youwen Guo, Yuxuan Liu, Yong Liu, Wei Wang, Ruiqi Xu, Jingyi Cheng, Lijia Tian, Wenbin Chen, Xun Xu
  • Patent number: 10860179
    Abstract: Described is a technology by which an interactive timeline user interface shows communication data aggregated from various sources (e.g., a telephone service, a website, an application and/or the like) in time order. To reduce the number of items in the timeline, certain items may be combined into a compressed item, e.g., items from the same source and/or of the same type may be rolled up into a rolled up item. The user may also interact to reply to a data item. For example, an editor may be provided upon interaction with a data item in the timeline, and the type of reply that is sent may automatically match the type of data item, (e.g., a text message reply to a text message).
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: December 8, 2020
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Steven W. Ickman, Lili Cheng
  • Publication number: 20200237678
    Abstract: The present invention discloses a lipid nanoparticle membrane composition, and the membrane composition comprises a cationic lipid, a neutral phospholipid, cholesterol, Tween, and a polyethylene glycol derivative, with a molar ratio of (25-35):(40-50):(15-25):(1-5):(1-5) in the membrane composition. Also disclosed is a method for preparing a lipid nanoparticle from the lipid nanoparticle membrane composition. The present invention provides a lipid nanoparticle membrane composition that is capable of increasing the stability of the nanoparticle itself, thereby promoting the release of a medicament in tumor tissue and reducing the probability of being degraded.
    Type: Application
    Filed: October 13, 2017
    Publication date: July 30, 2020
    Inventors: Guang CHENG, Wenzhong CHEN, Lili QIN
  • Publication number: 20200239835
    Abstract: A method for isolating and/or culturing cambium stem cells of panax ginseng is disclosed. The method comprises a step of treating tissues containing panax ginseng cambium with a compound of formula I. The present application further relates to cambium stem cells of panax ginseng obtained according to the method and use of such cambium stem cells in preparing a product for a suspension culture of panax ginseng. The method for isolating and/or culturing cambium stem cells of panax ginseng according to the present application can effectively separate the cambium stem cells of the panax ginseng which have unlimited cytodieresis ability and strong anti-adversity ability, can provide a basis for ultra-large volume liquid culture, which can significantly reduce production costs.
    Type: Application
    Filed: March 8, 2019
    Publication date: July 30, 2020
    Inventors: Dong Wu, Chensheng Dai, Lili Cheng, Huaide Chen, Minxian Liu, Lili Hou, Zhuohe Jiang, Yujia Liu, Yuanjian Ling
  • Publication number: 20200153918
    Abstract: The techniques discussed herein allow an agent that provides dialog-based services to converse with a user via any mode. A central service programmed to be able to communicate via any mode collects information from agents necessary to act on the agents' behalf. In order to ensure that an agent has a maximal presence across modes, the central service provides auxiliary services such as language translation, fidelity upgrading and/or downgrading, modal constraint conformation, etc. Moreover, the central service provides session tracking via user profiles stored at the intercom so that if a user changes a mode by which the user is conversing with an agent, the central service can keep the context of the conversation across the new mode. Furthermore, agents can communicate with other agents via the central service, allowing other agents to provide services to agents or to add their services to an ongoing dialog with a user.
    Type: Application
    Filed: January 16, 2020
    Publication date: May 14, 2020
    Inventors: Thomas Matthew LAIRD-MCCONNELL, Lili CHENG, James H. LEWALLEN, Justin CRANSHAW, Craig JENSEN, Steve ICKMAN, William L. PORTNOY, Qi LU, Daniel J. DRISCOLL
  • Patent number: 10587708
    Abstract: The techniques discussed herein allow an agent that provides dialog-based services to converse with a user via any mode. A central service programmed to be able to communicate via any mode collects information from agents necessary to act on the agents' behalf. In order to ensure that an agent has a maximal presence across modes, the central service provides auxiliary services such as language translation, fidelity upgrading and/or downgrading, modal constraint conformation, etc. Moreover, the central service provides session tracking via user profiles stored at the intercom so that if a user changes a mode by which the user is conversing with an agent, the central service can keep the context of the conversation across the new mode. Furthermore, agents can communicate with other agents via the central service, allowing other agents to provide services to agents or to add their services to an ongoing dialog with a user.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: March 10, 2020
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Thomas Matthew Laird-McConnell, Lili Cheng, James H. Lewallen, Justin Cranshaw, Craig Jensen, Steve Ickman, William L. Portnoy, Qi Lu, Daniel J. Driscoll
  • Patent number: 10580581
    Abstract: Methods for fabricating a structure that includes a metal-insulator-metal (MIM) capacitor and structures that include a MIM capacitor. The MIM capacitor includes a layer stack with a first electrode, a second electrode, and a third electrode. The layer stack includes a pilot opening extending at least partially through at least one of the first electrode, the second electrode, and the third electrode. A dielectric layer is arranged over the metal-insulator-metal capacitor, and includes a via opening extending vertically to the pilot opening. A via is arranged in the via opening and the pilot opening. The pilot opening has a cross-sectional area that is less than a cross-sectional area of the via opening.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: March 3, 2020
    Assignee: GLOBALFOUNDRIES INC.
    Inventors: Robert J. Fox, III, Lili Cheng, Roderick A. Augur
  • Publication number: 20200064976
    Abstract: Described is a technology by which an interactive timeline user interface shows communication data aggregated from various sources (e.g., a telephone service, a website, an application and/or the like) in time order. To reduce the number of items in the timeline, certain items may be combined into a compressed item, e.g., items from the same source and/or of the same type may be rolled up into a rolled up item. The user may also interact to reply to a data item. For example, an editor may be provided upon interaction with a data item in the timeline, and the type of reply that is sent may automatically match the type of data item, (e.g., a text message reply to a text message).
    Type: Application
    Filed: November 5, 2019
    Publication date: February 27, 2020
    Inventors: Steven W. ICKMAN, Lili CHENG
  • Publication number: 20200035495
    Abstract: Apparatus and methods of chemical-mechanical polishing of a layer on a wafer. A plurality of polishers arranged on a rotating plate, and a carrier is configured to hold the wafer and to place the layer in contact with the polishers. Each polisher includes a platen and a force-applying device operatively connected to the platen, and the force-applying device is configured to apply a variable force to the platen in order to change a rate of material removal over an area of the layer on the wafer contacted by a polishing pad carried by the platen.
    Type: Application
    Filed: July 25, 2018
    Publication date: January 30, 2020
    Inventors: Dewei Xu, Lili Cheng, Shinichiro Kakita, Ushasree Katakamsetty, Roderick A. Augur
  • Publication number: 20190378741
    Abstract: A chip bonding apparatus includes a chip separation unit, a chip alignment unit, a chip bonding unit and a bonding robotic arm unit. The bonding robotic arm unit includes a first bonding robotic arm unit and a second bonding robotic arm unit. The first bonding robotic arm unit includes a first motion stage, a first driver configured to drive the first motion stage and at least one first bonding robotic arm arranged on the first motion stage. The first bonding robotic arm is configured to suck up a chip from the chip separation unit and deliver it to the chip alignment unit. The second bonding robotic arm unit includes a second motion stage, a second driver configured to drive the second motion stage and at least one second bonding robotic arm arranged on the second motion stage.
    Type: Application
    Filed: February 27, 2018
    Publication date: December 12, 2019
    Inventors: Feibiao CHEN, Hai XIA, Yuebin ZHU, Hailin CHENG, Xiaoyu JIANG, Lili ZHAO, Donghao ZHANG
  • Patent number: 10466864
    Abstract: Described is a technology by which an interactive timeline user interface shows communication data aggregated from various sources (e.g., a telephone service, a website, an application and/or the like) in time order. To reduce the number of items in the timeline, certain items may be combined into a compressed item, e.g., items from the same source and/or of the same type may be rolled up into a rolled up item. The user may also interact to reply to a data item. For example, an editor may be provided upon interaction with a data item in the timeline, and the type of reply that is sent may automatically match the type of data item, (e.g., a text message reply to a text message).
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: November 5, 2019
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Steven W. Ickman, Lili Cheng
  • Publication number: 20190328763
    Abstract: A lipid nanoparticle for antisense oligonucleotides inhibiting bcl-2 and belonging to the technical field of biology. The lipid nanoparticle for antisense oligonucleotides inhibiting bcl-2 is prepared by coating an antisense oligonucleotide with a membrane material, and the nucleic acid sequence is 5?-TCT CCC AGC GTG CGC CAT-3? (SEQ ID NO: 1), or 5? UCU CCC AGC GTG CGC CAU 3? (SEQ ID NO: 2). And a method for preparing the same is provided. The nanoparticles have a fairly good inhibitory effect on the growth of tumor cells and specific target genes, and particularly have a fairly good inhibitory effect on KB cervical cancer cells.
    Type: Application
    Filed: October 13, 2017
    Publication date: October 31, 2019
    Inventors: Guang CHENG, Wenzhong CHEN, Lili QIN
  • Publication number: 20190148072
    Abstract: Methods for fabricating a structure that includes a metal-insulator-metal (MIM) capacitor and structures that include a MIM capacitor. The MIM capacitor includes a layer stack with a first electrode, a second electrode, and a third electrode. The layer stack includes a pilot opening extending at least partially through at least one of the first electrode, the second electrode, and the third electrode. A dielectric layer is arranged over the metal-insulator-metal capacitor, and includes a via opening extending vertically to the pilot opening. A via is arranged in the via opening and the pilot opening. The pilot opening has a cross-sectional area that is less than a cross-sectional area of the via opening.
    Type: Application
    Filed: November 16, 2017
    Publication date: May 16, 2019
    Inventors: Robert J. Fox, III, Lili Cheng, Roderick A. Augur
  • Patent number: 10250549
    Abstract: A mechanism for automatically organizing electronic messages is described herein. Social groups of a particular user that may be representative of topics, people, projects, and the like can be automatically learned based at least in part upon historical correspondence of the user. Moreover, messages can be automatically prioritized based at least in part upon historical correspondence patterns. Electronic messages may be presented to the user in accordance with group information and how important the messages are to the user.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: April 2, 2019
    Assignee: MICROSOFT TECHNOLOGY LICENSING, LLC
    Inventors: Andrzej Turski, Lili Cheng, Michael Anthony Affronti, Shane Williams
  • Publication number: 20180269273
    Abstract: Methods for contacting a metal-insulator-metal (MIM) capacitor, as well as structures including a MIM capacitor. A dielectric layer is formed on an electrode of a metal-insulator-metal capacitor. A via is formed that extends vertically through the dielectric layer to the electrode. A conductive plug is formed in the via that contacts the electrode. The dielectric layer is comprised of a polymer, such as polyimide.
    Type: Application
    Filed: March 20, 2017
    Publication date: September 20, 2018
    Inventors: Sunil Singh, Devender, Lili Cheng
  • Publication number: 20180131662
    Abstract: A mechanism for automatically organizing electronic messages is described herein. Social groups of a particular user that may be representative of topics, people, projects, and the like can be automatically learned based at least in part upon historical correspondence of the user. Moreover, messages can be automatically prioritized based at least in part upon historical correspondence patterns. Electronic messages may be presented to the user in accordance with group information and how important the messages are to the user.
    Type: Application
    Filed: January 5, 2018
    Publication date: May 10, 2018
    Inventors: Andrzej Turski, Lili Cheng, Michael Anthony Affronti, Shane Williams
  • Patent number: 9953087
    Abstract: A topic feed is generated for publication or distribution to a set of followers or recipients who have elected to receive the topic feed from the user or based on the subject matter content of a topic input in the topic feed. The topic feed is distributed and includes the topic input. Experts in subject matter can be identified based on the user's topic input and/or text in the topic feed that the followers interact with.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: April 24, 2018
    Assignee: Mircosoft Technology Licensing, LLC
    Inventors: Steven Ickman, Thomas Matthew Laird-McConnell, William Lawrence Portnoy, Christopher McConnell, Lili Cheng, David Arthur Raskino, Gregory Scott Melander
  • Patent number: 9866514
    Abstract: A mechanism for automatically organizing electronic messages is described herein. Social groups of a particular user that may be representative of topics, people, projects, and the like can be automatically learned based at least in part upon historical correspondence of the user. Moreover, messages can be automatically prioritized based at least in part upon historical correspondence patterns. Electronic messages may be presented to the user in accordance with group information and how important the messages are to the user.
    Type: Grant
    Filed: June 13, 2016
    Date of Patent: January 9, 2018
    Assignee: MICROSOFT TECHNOLOGY LICENSING, LLC
    Inventors: Andrzej Turski, Lili Cheng, Michael Anthony Affronti, Shane Williams
  • Publication number: 20170364834
    Abstract: The subject disclosure is directed towards a real-time or near real-time sentiment monitoring service. A set of rules such as keywords and data sources to crawl is provided to the monitoring service, which crawls the sources to obtain sentiment-related data for an entity, such as a corporation or product. Content items may be selected from the crawled data, and/or the data may be analyzed to provide results. The results may be displayed, such as on a content page, to quickly view the public's sentiment regarding the entity. The rules may be dynamically modified by a user or collaborating users to tune monitoring of the entity as desired, e.g., to obtain more relevant results.
    Type: Application
    Filed: September 5, 2017
    Publication date: December 21, 2017
    Inventors: Russell Allen HERRING, James H. LEWALLEN, Todd D. NEWMAN, David S. TANIGUCHI, Lili CHENG