Patents by Inventor Linda Dayem

Linda Dayem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090098615
    Abstract: Recombinant Escherichia coli host cells that comprise recombinant DNA expression vectors that drive expression of methylmalonyl CoA mutase from Propionibacterium shermanii or Streptomyces cinnamonensis as well as Propionibacterium shermanii epimerase can produce S-methylmalonyl CoA, a required substrate for the production of polyketides by most modular polyketide synthases not present in wild-type E. coli host cells.
    Type: Application
    Filed: November 5, 2007
    Publication date: April 16, 2009
    Inventors: Daniel SANTI, Larry Peck, Linda Dayem, James Kealey
  • Patent number: 7291486
    Abstract: Recombinant Escherichia coli host cells that comprise recombinant DNA expression vectors that drive expression of methylmalonyl CoA mutase from Propionibacterium shermanii or Streptomyces cinnamonensis as well as Propionibacterium shermanii epimerase can produce S-methylmalonyl CoA, a required substrate for the production of polyketides by most modular polyketide synthases not present in wild-type E. coli host cells.
    Type: Grant
    Filed: April 21, 2004
    Date of Patent: November 6, 2007
    Assignee: KOSAN Biosciences, Inc.
    Inventors: Daniel Santi, Linda Dayem, James Kealey
  • Patent number: 7011959
    Abstract: Recombinant E. coli host cells that comprise recombinant DNA expression vectors that drive expression of methylmalonyl CoA mutase from Propionibacterium shermanii or Streptomyces cinnamonensis as well as Propionibacterium shermanii epimerase can produce S-methylmalonyl CoA, a required substrate for the production of polyketides by most modular polyketide synthases and is not present in wild-type E. coli host cells.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: March 14, 2006
    Assignee: Kosan Biosciences, Inc.
    Inventors: Daniel Santi, Larry Peck, Linda Dayem, James Kealey
  • Publication number: 20040185541
    Abstract: Recombinant host cells that comprise recombinant DNA expression vectors that drive expression of a product and a precursor for biosynthesis of that product can be used to produce useful products such as polyketides in host cells that do not naturally produce the product or produce the product or precursor at low levels due to the absence of the precursor or the presence of the precursor in rate limiting amounts.
    Type: Application
    Filed: April 21, 2004
    Publication date: September 23, 2004
    Inventors: Daniel Santi, Linda Dayem, James Kealey
  • Publication number: 20020142401
    Abstract: Recombinant host cells that comprise recombinant DNA expression vectors that drive expression of a product and a precursor for biosynthesis of that product can be used to produce useful products such as polyketides in host cells that do not naturally produce the product or produce the product or precursor at low levels due to the absence of the precursor or the presence of the precursor in rate limiting amounts.
    Type: Application
    Filed: August 29, 2001
    Publication date: October 3, 2002
    Inventors: Daniel Santi, Linda Dayem, James Kealey