Abstract: An advanced electronic disease management system is disclosed. The system has been designed to provide medical offices and hospitals with easily accessible guidelines for managing primary and secondary prevention of medical conditions, such as vascular disease. The system allows for easy integration with existing electronic data stores as well as newly entered manual and electronic records. The system is suitable for use with well-known computer interface models, and can be rapidly integrated into existing medical practices. The system can include a computer system capable of receiving a plurality of patient information inputs and a plurality of medical standards inputs, and means for comparing the patient information inputs against the medical standards inputs to produce a recommendation output.

Abstract: A method is disclosed for measuring changes in vascular reactivity that seeks to overcome the aforementioned shortcomings. The method is non-invasive and allows for continuous or sustained monitoring of blood vessels. By measuring changes in vascular reactivity, information on endothelium-dependent vasorelaxation may be provided. Parameters such as skin temperature, heat flux, ambient temperature, movement, galvanic response and/or body acceleration may be monitored to indicate changes in vascular reactivity and to provide information concerning endothelical function of patients. Other information such as patient response to blood pressure medications and other types of medications, onset of congestive heart failure and other types of medical complications, and the occurrence of unstable angina may also be obtained.

Abstract: A cartridge assembly having a cylindrical body, with its forward end being packed down to form an annular flange, a hub fitted on the annular flange, a diaphragm seal positioned on the forward face of the annular flange and held in sealing position by the hub fitted on the annular flange, a piston slidably carried in the rearward portion of the body, a liquid medicament held in the body in the space between the diaphragm and the piston, the hub being made of transparent plastic material and having a first cylindrical portion having an internal diameter sized to fit over the annular flange of the cartridge, a second cylindrical portion extends from the first cylindrical portion and has a diameter less than the first cylindrical portion, a third cylindrical portion extends from the second cylindrical portion and has a diameter less than the second cylindrical portion, a fourth cylindrical portion extends from the third cylindrical portion and has a diameter less than the third cylindrical portion, the fourth cy

Abstract: An automatic injector training device comprising an automatic injector simulating assembly having a forward end arranged to be engaged with a muscle injection site of the user and an exterior periphery adapted to be manually gripped by a user. The assembly includes an outer structure and a movable structure mounted for movement with respect to the outer structure (1) from a storage position into an audible signal producing position in response to an actuating movement performed by the user while manually gripping the exterior periphery of the assembly and thereby maintaining the forward end of the assembly in engagement with the injection site and (2) from its audible signal producing position into its storage postion in response to a reset movement performed by the user.

Abstract: A medicament discharging device and an expendable clip thereon containing a plurality of medicament cartridges. Each of the cartridges comprises a container, a dosage of medicament in the container, a hypodermic needle sealingly contained in a sterile condition in cooperating relation with the container and a movable wall means at one end of the container operable when moved through a discharging stroke to cause the sharpened end of the needle to move outwardly out of sealingly contained relation and into the muscle tissue of a patient and the medicament dosage to move outwardly of the container into the opposite end of the needle and out of the sharpened end thereof into the muscle tissue of the patient.