Patents by Inventor Linda Greenbaum

Linda Greenbaum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION TREATMENT OF LIVER DISEASES USING INTEGRIN INHIBITORS
    Publication number: 20230060422
    Abstract: The invention provides a pharmaceutical combination including an ?v?1 integrin inhibitor and at least one additional therapeutic agent for preventing, delaying or treating liver diseases or disorders. The additional therapeutic agent may be an SGLT1/2 inhibitor, among a diverse selection of agents. For example, the pharmaceutical combination includes (S)-2-(4-methyltetrahydro-2H-pyran-4-carboxamido)-9-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl) nonanoic acid (Compound 1) and at least one additional therapeutic agent.
    Type: Application
    Filed: December 18, 2020
    Publication date: March 2, 2023
    Inventors: Kraig ANDERSON, Christopher BAILEY, Avirup BOSE, Jacob CHA, Nicole COOPER, Darren FINKELSTEIN, Linda GREENBAUM, Johannes HULL, Susan Caroline KIRKLAND, Katerina LEFTHERIS, Maureen REILLY, Peter TARSA, Chinweike UKOMADU
  • COMBINATION TREATMENT OF LIVER DISEASES USING INTEGRIN INHIBITORS
    Publication number: 20230055657
    Abstract: The invention provides a pharmaceutical combination including an ?v?1 integrin inhibitor and at least one additional therapeutic agent for preventing, delaying or treating liver diseases or disorders. The at least one additional therapeutic agent may be a farnesoid X receptor (FXR) agonist. For example, the pharmaceutical combination includes (S)-2-(4-methyltetrahydro-2H-pyran-4-carboxamido)-9-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)nonanoic acid (Compound 1) and 2-[3-({5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl}methoxy)-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1, 3-ben-zothiazole-6-carboxylic acid (tropifexor).
    Type: Application
    Filed: December 18, 2020
    Publication date: February 23, 2023
    Inventors: Kraig ANDERSON, Christopher BAILEY, Avirup BOSE, Jacob CHA, Nicole COOPER, Darren FINKELSTEIN, Linda GREENBAUM, Johannes HULL, Susan Caroline KIRKLAND, Katerina LEFTHERIS, Maureen REILLY, Peter TARSA, Chinweike UKOMADU
  • Methods of Treating Crohn's Disease with an Anti-NKG2D Antibody
    Publication number: 20190292265
    Abstract: The present invention is directed to methods for treating Crohn's Disease with an antibody that binds NKG2D. In particular, it relates to dosing regimens for administration of an anti-NGK2D antibody. It also relates to methods of selecting patients for treatment with an anti-NKG2D antibody.
    Type: Application
    Filed: August 17, 2017
    Publication date: September 26, 2019
    Inventors: Carrie Brodmerkel, Mark Curran, Linda Greenbaum, Shannon Telesco