Patents by Inventor Lionel Borkan

Lionel Borkan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8287904
    Abstract: A stable soft gel dosage form for acetylsalicylic acid (ASA), aspirin, is provided wherein soft gel capsules containing the ASA can be stored for prolonged periods under typical home storage conditions with better than 98% or 99% ASA integrity and with negligible physical or chemical deterioration of the soft gelatin capsule over the period of six months. A suspension of ASA in a monoglyceride component comprising more than about 50% glyceryl monooleate is packaged in a soft gelatin capsule, which can be substantially free of other components. The ASA in this composition is resistant to hydrolysis from water contained within the soft gelatin matrix or diffusing through the matrix. Methods of preparation and methods of use are also provided.
    Type: Grant
    Filed: August 19, 2010
    Date of Patent: October 16, 2012
    Inventor: Lionel Borkan
  • Publication number: 20120045507
    Abstract: A stable soft gel dosage form for acetylsalicylic acid (ASA), aspirin, is provided wherein soft gel capsules containing the ASA can be stored for prolonged periods under typical home storage conditions with better than 98% or 99% ASA integrity and with negligible physical or chemical deterioration of the soft gelatin capsule over the period of six months. A suspension of ASA in a monoglyceride component comprising more than about 50% glyceryl monooleate is packaged in a soft gelatin capsule, which can be substantially free of other components. The ASA in this composition is resistant to hydrolysis from water contained within the soft gelatin matrix or diffusing through the matrix. Methods of preparation and methods of use are also provided.
    Type: Application
    Filed: August 19, 2010
    Publication date: February 23, 2012
    Inventor: Lionel Borkan
  • Patent number: 4935243
    Abstract: In accordance with the present invention, there is provided a chewable, edible soft gelatin capsule which comprises a shell comprising water, gelatin, plasticizer, and an amount of hydrogenated starch hydrolysate effective to render said shell dispersible and soluble in the mouth of the user; and a soft gelatin capsule fill material in which an active ingredient, preferably a biologically-active agent, is dispersed or dissolved.
    Type: Grant
    Filed: December 19, 1988
    Date of Patent: June 19, 1990
    Assignee: Pharmacaps, Inc.
    Inventors: Lionel Borkan, Ira R. Berry, Dilip Shah
  • Patent number: 4795642
    Abstract: A controlled-release pharmaceutical unit dosage form is provided comprising a gelatin capsule enclosing a solid matrix formed by the cation-assisted gellation of a liquid fill incorporating vegatable gum and a pharmaceutically-active compound, as well as methods for the preparation thereof.
    Type: Grant
    Filed: August 17, 1987
    Date of Patent: January 3, 1989
    Assignee: Pharmacaps, Inc.
    Inventors: Jonathan M. Cohen, Ira R. Berry, Lionel Borkan
  • Patent number: 4708834
    Abstract: A controlled-release pharmaceutical unit dosage form is provided comprising a gelatin capsule enclosing a solid matrix formed by the cation-assisted gellation of a liquid fill incorporating a vegetable gum and a pharmaceutically-active compound, as well as methods for the preparation thereof.
    Type: Grant
    Filed: May 1, 1986
    Date of Patent: November 24, 1987
    Assignee: Pharmacaps, Inc.
    Inventors: Jonathan M. Cohen, Ira R. Berry, Lionel Borkan
  • Patent number: 4597885
    Abstract: Cosmetic unit dosage forms comprising encapsulated liquid blends of acidic and basic surfactants are provided. The blends are both high-foaming bath compositions and compatible with soft gelatin capsules.
    Type: Grant
    Filed: January 2, 1985
    Date of Patent: July 1, 1986
    Assignee: Pharmacaps, Inc.
    Inventors: Ira R. Berry, Dilip Shah, Lionel Borkan
  • Patent number: 4486412
    Abstract: Pharmaceutical unit dosage forms comprising dispersions of basic salts in a carrier mixture comprising polyalkylene glycols and a C.sub.2 -C.sub.5 polyol encapsulated in soft gelatin capsules are prepared without deleteriously affecting the stability of the capsules.
    Type: Grant
    Filed: March 15, 1983
    Date of Patent: December 4, 1984
    Assignee: Pharmacaps, Inc.
    Inventors: Dilip Shah, Lionel Borkan, Ira R. Berry